Aminolysis of 5-Phenyl-2-tetrazolylacetic Acid Ethyl Ester

It was shown using 5-phenyl-2-tetrazolylacetic acid ethyl ester as an example that aminolysis is a competitive method of synthesizing primary amides. The efficiency of aminolysis by primary amines is linked to the basicity of the initial amine. Highly basic amines display more high reactivity independent of the spatial structure of the substituent. Reaction of the investigated ester with secondary amines occurs ambiguously.     

Formation of conic cusps at the surface of liquid metal in electric field

The formation dynamics is studied for a singular profile of a surface of an ideal conducting fluid in an electric field. Self-similar solutions of electrohydrodynamic equations describing the fundamental process of formation of surface conic cusps with angles close to the Taylor cone angle 98.6° are obtained. The behavior of physical quantities (field strength, fluid velocity, surface curvature) near the singularity is established.     

Theoretical Probing of Deltahedral closo‐AuroBoranes BxAux2‐ (x = 5—12)

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Investigation of skin secretory peptidome of <Emphasis Type="Italic">Rana lessonae</Emphasis> frog by mass spectrometry

Amphibian skin secretion represents a cerain scientific interest as a source of biologically active natural peptides. In the present research skin peptidome of wide-spread European frog Rana lessonae (Camerano, 1882) was studied for the first time ever. Peptide sequencing was accomplished with Fourier transform ion cyclotron resonance mass spectrometer in collision-induced and electron capture dissociation modes. A portion of amphibian peptides contains intramolecular C-terminal disulfide cycle which obstructs mass spectrometric sequencing. Two methods were utilized to overcome this difficulty: reduction with dithiotreithol followed by thiol group alkylation and oxidation into sulfonic acid groups with performic acid. Integrated approach employed in the present study allowed the identification of 49 peptides (of 6 to 37 amino acid residues), including 19 novel species.