全文获取类型
收费全文 | 24315篇 |
免费 | 3762篇 |
国内免费 | 2630篇 |
专业分类
化学 | 16934篇 |
晶体学 | 296篇 |
力学 | 1439篇 |
综合类 | 239篇 |
数学 | 2659篇 |
物理学 | 9140篇 |
出版年
2024年 | 78篇 |
2023年 | 504篇 |
2022年 | 818篇 |
2021年 | 877篇 |
2020年 | 984篇 |
2019年 | 904篇 |
2018年 | 752篇 |
2017年 | 726篇 |
2016年 | 1100篇 |
2015年 | 1036篇 |
2014年 | 1292篇 |
2013年 | 1672篇 |
2012年 | 2074篇 |
2011年 | 2076篇 |
2010年 | 1425篇 |
2009年 | 1366篇 |
2008年 | 1529篇 |
2007年 | 1403篇 |
2006年 | 1342篇 |
2005年 | 1085篇 |
2004年 | 869篇 |
2003年 | 721篇 |
2002年 | 623篇 |
2001年 | 519篇 |
2000年 | 512篇 |
1999年 | 590篇 |
1998年 | 487篇 |
1997年 | 428篇 |
1996年 | 436篇 |
1995年 | 387篇 |
1994年 | 357篇 |
1993年 | 325篇 |
1992年 | 269篇 |
1991年 | 229篇 |
1990年 | 235篇 |
1989年 | 159篇 |
1988年 | 119篇 |
1987年 | 84篇 |
1986年 | 97篇 |
1985年 | 65篇 |
1984年 | 37篇 |
1983年 | 39篇 |
1982年 | 37篇 |
1981年 | 21篇 |
1980年 | 8篇 |
1979年 | 6篇 |
1976年 | 1篇 |
1957年 | 4篇 |
排序方式: 共有10000条查询结果,搜索用时 11 毫秒
951.
Enzymatic profiling system in a small-molecule microarray 总被引:1,自引:0,他引:1
[reaction: see text] We have developed a microarray-based strategy for detection of three major classes of hydrolytic enzymes on the basis of their catalytic activities. This enables the sensitive detection of proteins not merely by their bindings but rather by their enzymatic activities. This may provide a valuable tool for screening, identification, and characterization of new enzymes in a high-throughput fashion. 相似文献
952.
Fluoroalkanesulfonyl azides reacted with morpholine giving unexpectedly N-fluoroalkanesulfonyl-N-morpholino diazenes, which were fully characterized by using spectral methods and X-ray diffraction analysis. 相似文献
953.
Guo‐Fu Chen Chang‐Heng Tan Zhu‐Lian Li Shan‐Hao Jiang Da‐Yuan Zhu 《Helvetica chimica acta》2003,86(3):787-792
Pseudolarolides O ( 1 ) and P ( 2 ), two novel triterpenoids with a cycloartane‐type framework, were isolated from the seeds of Pseudolarix kaempferi Gord. (Pinaceae). Their structures were elucidated as (16R,23S,25R)‐16,23‐epoxy‐3,4 : 9,10‐disecocycloartan‐1(10),9(11)‐diene‐3(4),26(23)‐diolide ( 1 ), and (9S,16R,23S,25R)‐1,9 : 16,23‐diepoxy‐8,9 : 9,10‐disecocycloartan‐1(29),5(6),10(19)‐triene‐3(4),26(23)‐diolide ( 2 ), respectively, on the basis of spectroscopic techniques and X‐ray‐diffraction studies. 相似文献
954.
Xiao Ying Xu Feng Cheng Jian Hua Shen Xiao Min Luo Li Li Chen Li Duo Yue Yi Du Fei Ye Shan Hao Jiang Da Yuan Zhu Hua Liang Jiang Kai Xian Chen 《International journal of quantum chemistry》2003,93(6):405-410
Docking simulation of 18 agonists with the ligand binding pocket (LBP) of PPARγ has been performed. The binding conformations and binding affinities of these agonists were obtained by use of the flexible docking protocol FlexX. Test compound calculations indicated that FlexX can reproduce the binding conformation of the crystal structure (root mean square deviation = 1.43 Å); moreover, the predicted binding affinities correlate well with the activities of these agonists. The interaction model and pharmacophore of PPARγ agonists were derived and the difference in biologic activities of these agonists can be well explained. The PPARγ agonists must have both polar head and the hydrophobic tail, which form hydrogen bonds and hydrophobic contacts with hydrophilic and hydrophobic regions of the LBP of PPARγ, respectively. In addition, a suitable linker is also necessary. © 2003 Wiley Periodicals, Inc. Int J Quantum Chem 93: 405–410, 2003 相似文献
955.
956.
Haiying Zhang Jiarou Peng Shiqi Peng Guowang Wu Duenhua Dai Guozheng Zhu 《Journal of mass spectrometry : JMS》1992,27(1):50-52
The reactions of sulphur with phosphine and phosphite were investigated by low-energy electron impact mass spectrometry and fast atom bombardment mass spectrometry. A previously reported mechanism of the Ph3P–S8 reaction was supported and a possible mechanism for the (PhO)3P–S8 reaction is proposed. 相似文献
957.
958.
959.
960.
合成了三(三苯基氧膦)合硝酸镧络合物, 经鉴定确定络合物化学式为La(NO_3)_3·3ph_3PO·C_2H_5OH·CHCl_3。其中C_2H_5OH和CHCl_3为溶剂化分子。经X射线单晶衍射, 测定了该络合物属单斜晶系P2_1/n空间群, 晶体学参数如下a=1.3111(5) nm Z=4b=2.5075(10) nm F(000)=2687.65c=1.8725(6) nm μ吸收系数=9.83(cm~(-1))β=98.53(3)° d计算=1.45 gcm~(-3)V=6.088 nm d实验=1.43 gcm~(-3)La与9个氧直接配位, 其中六个氧来自三个双卤配位硝酸根, 另三个氧分别由三个苯基氧膦上的膦酰基所提供。La-O平均键长0.2549 nm。 相似文献