In vitro anticomplementary activity and quality evaluation of dried blossoms of Inula nervosa Wall. from different geographical origins

Blossoms of Inula nervosa Wall. (BINW) are traditionally used as an analgesic and antitussive in China. In this study, in vitro anticomplementary activities of crude extract from BINW in 21 batches and of extracts of four monomeric compounds were evaluated by the classical pathway. The effect of the region of origin on the quality of BINW was evaluated by fingerprint analysis for the first time. Furthermore, chemometric methods including similarity analysis and principal component analysis were employed to evaluate the quality of BINW. The nine major monomeric compounds were quantitated by ultra‐high‐performance liquid chromatography. All nine analytes demonstrated excellent linearity with recoveries ranging from 97.25% to 102.76%. The limits of detection and quantification were 0.07–12.20 μg/mL and 0.22–40.27 μg/mL, respectively. Results indicate that different regions of origin have a significant effect on the quality of BINW. Fingerprint analysis in combination with chemometrics and multi‐ingredient determination is an efficient and reliable approach for quality evaluation. The BINW samples from Yunnan had the highest ratio of 1,5‐dicaffeoylquinic acid and thymol; they also exhibited significantly higher anticomplementary activity than those from three other areas. This study successfully established a rapid and efficient method to evaluate the quality and biological activity of BINW.     

Invariant Einstein metrics on generalized Wallach spaces

Invariant Einstein metrics on generalized Wallach spaces have been classified except SO(k + l+ m)/SO(k) × SO(l) × SO(m). In this paper, we first give a survey on the study of invariant Einstein metrics on generalized Wallach spaces, and prove that there are infinitely many spaces of the type SO(k + l + m)/SO(k)× SO(l) × SO(m) admitting exactly two, three, or four invariant Einstein metrics up to a homothety.     

Non-trivial m-quasi-Einstein metrics on quadratic Lie groups

We call a metric m-quasi-Einstein if \({Ric_X^m}\) (a modification of the m-Bakry–Emery Ricci tensor in terms of a suitable vector field X) is a constant multiple of the metric tensor. It is a generalization of Einstein metrics which contain Ricci solitons. In this paper, we focus on left-invariant vector fields and left-invariant Riemannian metrics on quadratic Lie groups. First we prove that any left-invariant vector field X such that the left-invariant Riemannian metric on a quadratic Lie group is m-quasi-Einstein is a Killing vector field. Then we construct infinitely many non-trivial m-quasi-Einstein metrics on solvable quadratic Lie groups G(n) for m finite.     

磁耦合谐振式超导无线电能传输线圈错动对传输效率的影响仿真

超导以其低阻抗的特性,受到了广泛关注和应用.将超导线圈引入无线电能传输系统中,能够提升其传输性能.本文通过有限元仿真软件COMSOL Multiphysics对超导线圈错动对无线电能传输系统传输性能的影响进行了仿真,得出超导无线电能传输性能较之传统的在线圈错动时性能更好,在大功率的使用场合中能更好的适应实际情况,减少损耗,提升传输质量,为超导无线电能传输技术的应用提供了一定的参考依据.     

有机可溶性高折射率聚酰胺酰亚胺的合成与性能

采用含硫二胺1,4-双(4-氨基苯硫基)苯(2SPDA)与偏苯三酸酐反应制备了一种含硫二酸化合物1,4-双(4-三甲酰亚胺基苯硫基)苯(BTPB).以此二酸为原料与两种高硫含量二胺单体,4,4′-双(4-氨基苯硫基)二苯硫醚(3SDA)以及2,7-双(4-氨基苯硫基)噻蒽(APTT)通过高温缩聚法制备了两种聚酰胺酰亚胺(PAI).制备的PAI在室温下可溶解于N-甲基-2-吡咯烷酮(NMP)中.PAI薄膜的起始热分解温度(T5%)超过440℃,玻璃化转变温度(Tg)大于190℃.PAI薄膜在波长大于500nm的可见光区具有良好的透明性.此外,PAI薄膜的折射率大于1.73,双折射小于0.04.     

微波-超声波协同一步提取衍生化-气相色谱-质谱联用快速分析中药材猫爪草中的脂肪酸

建立了一种微波-超声波协同一步提取衍生化、气相色谱-质谱联用快速测定中药材猫爪草中低含量脂肪酸的方法。以总脂肪酸的色谱峰面积为响应指标,采用响应曲面法优化了主要工艺参数,其结果为: 猫爪草粉末5.0 g,正己烷50.0 mL,微波功率500 W,反应温度50 ℃,催化剂用量0.30 g,甲醇用量4.0 mL,提取衍生化时间8 min。以内标法定量各个脂肪酸的含量,一步提取衍生化法获得的总脂肪酸峰面积((3.327±0.023)×107, n=3)和总不饱和脂肪酸含量((13.59±0.30) mg/g, n=3)明显高于传统方法((2.410±0.036)×107(n=3)和(12.05±0.34) mg/g(n=3))。该方法简化了复杂的样品处理过程,缩短了反应时间,降低了分析成本,改善了提取和衍生化效率,尤其是减少了不饱和脂肪酸的氧化和分解。该方法具有简单、快速和实用性的特点,是一种极具应用潜力的中药材中低含量脂肪酸的快速分析方法。     

细胞色素P450酶催化的烷烃选择性羟化

碳氢键选择氧化是合成化学领域的重要课题,其中烷烃选择性羟化反应更是面临着化学选择性、区域选择性和立体选择性等多重挑战.细胞色素P450酶广泛分布于动植物和微生物体内,是公认的多功能生物氧化催化剂. P450酶对惰性C—H键的选择性氧化具有独特优势,在催化烷烃选择性羟化反应方面拥有巨大潜力.本综述简述了P450单加氧酶及其催化烷烃选择性羟化的反应机理,梳理了来自CYP153家族、CYP52家族和其他家族的天然P450酶催化各类烷烃底物的氧化反应和选择性,讨论了理性设计和定向进化策略在开发烷烃羟化P450突变酶过程中的经典案例,介绍了底物工程、诱饵分子、双功能小分子协同催化等几种化学活化P450酶的策略及其在烷烃羟化上的应用,探讨了P450酶在烷烃选择性羟化方面所面临的挑战和解决途径,并展望了其应用前景.     

LiNbO3无谐振腔式电光调制混合型光学双稳态实现条件的研究

本文简介以LiNbO₃为非线性介质,利用电光振幅调制特性实现了LiNbO₃晶体混合型光学双稳态,并在不同的条件下测试了不同的光学双稳态滞后回线和调制函数曲线,首次提出“调制函数曲线平移”问题的方法。用此一性质可将偏置电压调制为零省去偏置系统,利于系统集成,为实现无偏压双稳系统指明了方向。     

铂（铂—铼）与氧化铝相互作用的研究：Ⅰ.氯的作用

采用PASCA、IR、化学分析及微反等技术,研究Pt/Al_2O_3和Pt-Re/Al_2O_3体系中金属与载体之间的相互作用。结果表明:氯在铂、铼与氧化铝之间的相互作用及对催化剂芳构化活性的影响方面起着十分重要的作用。在没有氯存在的情况下,铂(或铂-铼)与氧化铝之间是不存在相互作用的。当浸渍液中存在氯时,铂以[PtCl_6]~(2-)络离子形式取代氧化铝表面上某些活泼OH~-基,生成稳定的金属—载体相互作用复合物(MSIC)。而生成稳定MSIC的合适盐酸浓度为0.4 mol/L。这一结果与文献报导是一致的。 实验结果还表明,在探讨金属与载体之间的相互作用时,非金属元素(如氯等)是一个十分重要而不可忽视的因素。