三线摆摆线质量对转动惯量精确测量的影响

三线摆法是测量转动惯量的常用方法, 理论上通常都是把摆线作理想处理(即摆线质量趋于0), 但在工程测量中, 被测工件往往较重, 摆线不再是轻质细线, 摆线质量势必会对空载悬盘的转动惯量测量产生影响. 本文应用哈密顿原理和变量替换, 导出三线摆摆线的变张力弦振动方程, 通过对摆线与悬盘连接点(x=0)的运动状态讨论, 推得摆线质量不能忽略情形下的对称式三线摆的转动惯量计算式, 并借助于MATLAB 软件快速便利地进行计算.     

关于左手性介质几何光学的研究(一)

根据几何光学中的费马原理和完善成像原理研究了光线经过正负折射率界面时的传播特性,推导了单负折射率完善成像的曲面方程,讨论了单块负折射率透镜成像特性的一些缺陷及改进方案,依此指出了最短时间原理的适用范围的局限性和利用左手性介质制作光学器件的优越性,为进一步研究左手性介质的光学特性和相关光学器件设计提供了理论基础.     

直接膨胀供液制冷系统性能可视化研究

对直接膨胀供液制冷系统的传热性能进行了理论分析,建立了相应的数学模型.在保温体内对-5℃、0℃、5℃、10℃、15℃、20℃的工况进行了实验.分别测得制冷系统的压力、风量、制冷量、及功耗等技术参数,得到在环境温度一定的情况下的传热系数和制冷量的变化关系.并对蒸发器内制冷剂流动状态进行观察.实验表明:直接膨胀供液制冷系统...     

Discovery of a potent,selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy

Protein tyrosine phosphatase 1B (PTP1B) is an enzyme that downregulates the insulin receptor. Inhibition of PTP1B is expected to improve insulin action, and the design of small molecule PTP1B inhibitors to treat type II diabetes has received considerable attention. In this work, NMR-based screening identified a nonselective competitive inhibitor of PTP1B. A second site ligand was also identified by NMR-based screening and then linked to the catalytic site ligand by rational design. X-ray data confirmed that the inhibitor bound with the catalytic site in the native, "open" conformation. The final compound displayed excellent potency and good selectivity over many other phosphatases. The modular approach to drug design described in this work should be applicable for the design of potent and selective inhibitors of other therapeutically relevant protein tyrosine phosphatases.     

SOLVING THE FREE BOUNDARY PROBLEM IN CONTINUOUS CASTING BY USING BOUNDARY ELEMENT METHOD

ＳＯＬＶＩＮＧＴＨＥＦＲＥＥＢＯＵＮＤＡＲＹＰＲＯＢＬＥＭＩＮＣＯＮＴＩＮＵＯＵＳＣＡＳＴＩＮＧＢＹＵＳＩＮＧＢＯＵＮＤＡＲＹＥＬＥＭＥＮＴＭＥＴＨＯＤＬｉＹａｏｙｏｎｇ（李耀勇）；ＺｈａｎｇＺｈｉｌｉ（张自立）（ＲｅｃｅｉｖｅｄＪｕｎｅ，１８，１９...     

Transport modeling of membrane extraction of chlorinated hydrocarbon from water for ion mobility spectrometry

Membrane-extraction Ion Mobility Spectrometry (ME-IMS) is a feasible technique for the continuous monitoring of chlorinated hydrocarbons in water. This work studies theoretically the time-dependent characteristics of sampling and detection of trichloroethylene (TCE). The sampling is configured so that aqueous contaminants permeate through a hollow polydimethylsiloxane (PDMS) membrane and are carried away by a transport gas flowing through the membrane tube into IMS analyzer. The theoretical study is based on a two-dimensional transient fluid flow and mass transport model. The model describes the TCE mixing in the water, permeation through the membrane layer, and convective diffusion in the air flow inside membrane tube. The effect of various transport gas flow rates on temporal profiles of IMS signal intensity is investigated. The results show that fast time response and high transport yield can be achieved for ME-IMS by controlling the flow rate in the extraction membrane tube. These modeled time-response profiles are important for determining duty cycles of field-deployable sensors for monitoring chlorinated hydrocarbons in water.     

Quantitative coherence analysis with an X-ray Talbot–Lau interferometer

Differential phase-contrast (DPC) X-ray imaging has been performed in the Talbot–Lau configuration, in which the X-ray source was a combination of an absorption grating and a laboratory X-ray generator. We report here quantitative analysis of partial coherence effects on the X-ray Talbot–Lau interferometer. Based on the visibility of the self-image, the well-known geometry condition is reproduced. It is shown that effects of partial coherence are determined by the opening ratio of the source grating, and that the effects are independent of the Talbot order and the type of the phase grating, a condition quite different from those in a Talbot interferometer. A possible explanation is discussed from the point of view of the effective spatial coherence length. Taking into account the available X-ray flux and experimental fluctuations, we present the optimum opening ratio. Furthermore, we mention that our results can also be successfully used to discuss the properties of a multiline X-ray source.     

基于典型工况的半导体制冷系统优化方式探讨

半导体制冷的特殊性,使制冷优化探讨对其工程应用具有重要指导意义.文中阐述了作为制冷片工作参数优化依据的最大效率E、等增量I、等功率P、综合最佳S、最大制冷量Q和最大温差T六种典型制冷工况.工况对比分析指出,温差亦是影响制冷性能的重要因素.在讨论各工况应用场合和制冷片损坏机理的基础上.探讨了温差优化和供电与控制方式优化措...     

基于磁光调制偏振光的空间方位失调角高精度测量新方法

调制偏振光可以作为方位信息的载体,实现方位角度信息的传递,在军事、航天和生物医药等领域有广泛的应用前景.阐述了基于磁光调制偏振光的方位失调角测量原理,分析了现有测量原理中的误差来源.为了从理论方法上提高测量精度,提出了直接计算的方法,将磁光调制后的光强信号直接进行取极值点处理,建立了失调角与极值点之间的方程,详细分析了...     

2-乙酰氨基-3-苯基-N-苯基-丙烯酰胺衍生物的电子轰击质谱研究

本文报道了6种新的丙烯酰胺衍生物的EI谱。在精确质量测量和B/E,B~2/E联动扫描亚稳离子测定的基础上,着重讨论了该类化合物的共同质谱特征:如分子离子失去H_2O的成环反应;产物离子的开环反应;分子内的氢重排反应等。同时,利用Hammett方程讨论了化合物中N-苯基端苯环上不同取代基对特定碎片离子强度的影响