全文获取类型
收费全文 | 6429篇 |
免费 | 1301篇 |
国内免费 | 1099篇 |
专业分类
化学 | 5034篇 |
晶体学 | 173篇 |
力学 | 402篇 |
综合类 | 67篇 |
数学 | 716篇 |
物理学 | 2437篇 |
出版年
2024年 | 33篇 |
2023年 | 219篇 |
2022年 | 384篇 |
2021年 | 346篇 |
2020年 | 393篇 |
2019年 | 369篇 |
2018年 | 299篇 |
2017年 | 260篇 |
2016年 | 332篇 |
2015年 | 386篇 |
2014年 | 395篇 |
2013年 | 488篇 |
2012年 | 598篇 |
2011年 | 555篇 |
2010年 | 365篇 |
2009年 | 370篇 |
2008年 | 424篇 |
2007年 | 384篇 |
2006年 | 320篇 |
2005年 | 292篇 |
2004年 | 190篇 |
2003年 | 185篇 |
2002年 | 184篇 |
2001年 | 160篇 |
2000年 | 144篇 |
1999年 | 119篇 |
1998年 | 85篇 |
1997年 | 75篇 |
1996年 | 90篇 |
1995年 | 66篇 |
1994年 | 55篇 |
1993年 | 48篇 |
1992年 | 39篇 |
1991年 | 28篇 |
1990年 | 31篇 |
1989年 | 19篇 |
1988年 | 14篇 |
1987年 | 12篇 |
1986年 | 12篇 |
1985年 | 11篇 |
1984年 | 10篇 |
1983年 | 14篇 |
1982年 | 5篇 |
1981年 | 2篇 |
1979年 | 4篇 |
1978年 | 2篇 |
1973年 | 3篇 |
1968年 | 1篇 |
1957年 | 2篇 |
1936年 | 1篇 |
排序方式: 共有8829条查询结果,搜索用时 15 毫秒
71.
72.
该文在M/M/c排队驱动系统中加入工作休假策略,研究了单重工作休假多服务台排队驱动的流体模型.利用拟生灭过程和矩阵几何解法得到驱动系统稳态队长分布.构建净输入率结构,导出流体模型的稳态联合分布函数满足的的矩阵微分方程组,进而利用Laplace-Stieltjes变换(LST)方法得到稳态下缓冲器库存量的空库概率及均值表... 相似文献
73.
本文讨论了二叉树期权市场的无套利条件,引入有随机因素存在的二叉树欧式期权定价模型,并推出单阶段、多阶段情况下欧式期权的计算公式,证明了多阶段市场未定权益的重要性质. 相似文献
74.
75.
ICP-MS测定中草药狼毒中稀土和微量元素 总被引:3,自引:3,他引:0
研究了电感耦合等离子体质谱法(ICP-MS)测定中草药狼毒中稀土和微量元素的方法,样品处理通过低温灰化方法与硝酸-过氧化氢消解方法比较,实验确认微量元素采用低温灰化法制备样品, 稀土元素采用酸消化法制备样品,可以满足该方法检测要求,具有测试方法准确、快速等优点。 方法的准确度在1.21%~15.15%, 精密度在0.38%~8.54%之间。 该方法完全可以满足中草药样品中稀土和微量元素检测要求。 相似文献
76.
77.
Kunqian Mu Kaiwen Jiang Yue Wang Zihan Zhao Song Cang Kaishun Bi Qing Li Ran Liu 《Molecules (Basel, Switzerland)》2022,27(3)
β-cyclodextrin has a unique annular hollow ultrastructure that allows encapsulation of various poorly water-soluble drugs in the resulting cavity, thereby increasing drug stability. As a bioactive molecule, the metabolism of β-cyclodextrin is mainly completed by the flora in the colon, which can interact with API. In this study, understanding the in vivo fate of β-cyclodextrin, a LC-MS/MS method was developed to facilitate simultaneous quantitative analysis of pharmaceutical excipient β-cyclodextrin and API dextromethorphan hydrobromide. The established method had been effectively used to study the pharmacokinetics, tissue distribution, excretion, and metabolism of β-cyclodextrin after oral administration in rats. Results showed that β-cyclodextrin was almost wholly removed from rat plasma within 36 h, and high concentrations of β-cyclodextrin distributed hastily to organs with increased blood flow velocities such as the spleen, liver, and kidney after administration. The excretion of intact β-cyclodextrin to urine and feces was lower than the administration dose. It can be speculated that β-cyclodextrin metabolized to maltodextrin, which was further metabolized, absorbed, and eventually discharged in the form of CO2 and H2O. Results proved that β-cyclodextrin, with relative low accumulation in the body, had good safety. The results will assist further study of the design and safety evaluation of adjuvant β-cyclodextrin and promote its clinical development. 相似文献
78.
Sumeng Wang Yue Luo Wei Jiang Xiaomeng Li Qingsheng Qi Quanfeng Liang 《Molecules (Basel, Switzerland)》2022,27(3)
Several strategies, including inducer addition and biosensor use, have been developed for dynamical regulation. However, the toxicity, cost, and inflexibility of existing strategies have created a demand for superior technology. In this study, we designed an optogenetic dual-switch system and applied it to increase polyhydroxybutyrate (PHB) production. First, an optimized chromatic acclimation sensor/regulator (RBS10–CcaS#10–CcaR) system (comprising an optimized ribosomal binding site (RBS), light sensory protein CcaS, and response regulator CcaR) was selected for a wide sensing range of approximately 10-fold between green-light activation and red-light repression. The RBS10–CcaS#10–CcaR system was combined with a blue light-activated YF1–FixJ–PhlF system (containing histidine kinase YF1, response regulator FixJ, and repressor PhlF) engineered with reduced crosstalk. Finally, the optogenetic dual-switch system was used to rewire the metabolic flux for PHB production by regulating the sequences and intervals of the citrate synthase gene (gltA) and PHB synthesis gene (phbCAB) expression. Consequently, the strain RBS34, which has high gltA expression and a time lag of 3 h, achieved the highest PHB content of 16.6 wt%, which was approximately 3-fold that of F34 (expressed at 0 h). The results indicate that the optogenetic dual-switch system was verified as a practical and convenient tool for increasing PHB production. 相似文献
79.
无水坝抽水蓄能系统利用封闭容器内的高压气体构建虚拟水坝,是兼具压缩空气储能和抽水蓄能优点的新型储能系统。但该系统的封闭容器内水和气在高压状态共存有可能造成水中溶气,从而对水轮机造成汽蚀等破坏。本文采用实际气体状态方程及分子动力学模拟方法,研究了宽广的压力、温度范围下气体在水中的溶解及扩散规律,揭示了水中气体溶解量随时间和水深的变化规律。研究结果表明释能结束后保证水-气共容舱内剩余水的高度大于0.5 m时,高压溶气不会对水轮机产生危害,该结论对系统的工程应用及推广具有指导意义。 相似文献
80.
The etch-stop structure including the in-situ SiN and AlGaN/GaN barrier is proposed for high frequency applications.The etch-stop process is realized by placing an in-situ SiN layer on the top of the thin AlGaN barrier.F-based etching can be self-terminated after removing SiN,leaving the AlGaN barrier in the gate region.With this in-situ SiN and thin barrier etch-stop structure,the short channel effect can be suppressed,meanwhile achieving highly precisely controlled and low damage etching process.The device shows a maximum drain current of 1022 mA/mm,a peak transconductance of 459 mS/mm,and a maximum oscillation frequency(fmax)of 248 GHz. 相似文献