Study on chemical constituents of an edible mushroom Volvariella volvacea and their antitumor activity in vitro

Abstract

Phytochemical investigation of the fruiting body of Volvariella volvacea led to the isolation of a new furanone, 2(5H)-furanone-4-propionic acid named volvafuranone A (1), together with twelve known compounds (2–13). Compounds 2–7, 9–11 were isolated from this mushroom for the first time. The isolated compounds were assessed for their cytotoxicity against four human tumour lines (SGC-7901, PC-3M, MCF-7, HepG-2), and the results showed that compound 2, 3, 12, 13 have significant cytotoxicity with IC₅₀ values of 5.90?μM (HepG-2), 20.72?μM (HepG-2), 27.98?μM (PC-3M) and 23.15?μM (PC-3M), respectively.     

Co掺杂纳米ZnO微结构的正电子湮没研究

利用正电子湮没技术研究了10 at.% Co掺杂的Co₃O₄/ZnO纳米复合物中退火对缺陷的影响. 利用X射线衍射(XRD)测量了Co₃O₄/ZnO纳米复合物的结构和晶粒尺寸. 随着退火温度升高,Co₃O₄相逐步消失,ZnO晶粒尺寸也有显著增加. 经过1000 ℃以上退火后,Co₃O₄相完全消失,并出现了CoO的岩盐结构. 正电子湮没寿命测量显示出Co₃O₄ /ZnO纳米复合物中存在大量的Zn空位和空位团. 这些空位缺陷可能存在于纳米复合物的界面区域. 当退火温度达到700 ℃后Zn空位开始恢复,空位团也开始收缩. 900 ℃以上退火后,所有空位缺陷基本消失,正电子寿命接近ZnO完整晶格中的体态寿命值. 符合多普勒展宽谱测量也显示Co₃O₄ /ZnO纳米复合物经过900 ℃以上退火后电子动量分布与单晶ZnO基本一致,表明界面缺陷经过退火后得到消除. 关键词： ZnO 界面缺陷 正电子湮没     

Synthesis, structure and electrical properties of Cu3.21Ti1.16Nb2.63O12 and the CuOx-TiO2-Nb2O5 pseudoternary phase diagram

Subsolidus phase relations in the CuO_x-TiO₂-Nb₂O₅ system were determined at 935 °C. The phase diagram contains one new phase, Cu_3.21Ti_1.16Nb_2.63O₁₂ (CTNO) and one rutile-structured solid solution series, Ti_1−3xCu_xNb_2xO₂: 0<x<0.2335 (35). The crystal structure of CTNO is similar to that of CaCu₃Ti₄O₁₂ (CCTO) with square planar Cu²⁺ but with A site vacancies and a disordered mixture of Cu⁺, Ti⁴⁺ and Nb⁵⁺ on the octahedral sites. It is a modest semiconductor with relative permittivity ∼63 and displays non-Arrhenius conductivity behavior that is essentially temperature-independent at the lowest temperatures.     

异质化带宽分配下的复杂网络数据流负载问题研究

研究了带有连接边传输容量(带宽)约束的复杂网络上如何提升网络数据流负载问题. 在网络连接边带宽资源总量固定的条件下, 提出了一种异质化带宽分配方案. 引入 "受控边" 概念, 通过加入适当比例的 "受控边", 重新分配带宽资源, 并结合具有拥塞感知能力路由策略的数据流量模型, 利用带宽分配调节数据流量走向, 提高了带宽利用效率, 最终使得网络整体的负载能力较带宽匀质化分配时有显著提升. 分别在Barabási-Albert无标度网络和Watts-Strogtz (WS)小世界网络平台上仿真, 发现按照本文的带宽分配方案, WS小世界网络中节点连接边带宽与网络负载有较强的相关性, 节点连接边带宽分配最均衡的时候, 网络负载能力达到最大. 关键词： 异质化带宽分配 负载 介数 受控边     

Exponential Synchronization of Uncertain Complex Dynamical Networks with Delay Coupling

This paper studies the global exponential synchronization of uncertain complex delayed dynamical networks. The network model considered is general dynamical delay networks with unknown network structure and unknown coupling functions but bounded. Novel delay-dependent linear controllers are designed via the Lyapunov stability theory. Especially, it is shown that the controlled networks are globally exponentially synchronized with a given convergence rate. An example of typical dynamical network of this class, having the Lorenz system at each node, has been used to demonstrate and verify the novel design proposed. And, the numerical simulation results show the effectiveness of proposed synchronization approaches.     

Enhancing synchronizability by rewiring networks

<正>According to different forms of synchronized region,complex networks are divided into typeⅠ(unbounded synchronization region) and typeⅡ(bounded synchronization region) networks.This paper presents a rewiring algorithm to enhance the synchronizability of typeⅠand typeⅡnetworks.By utilizing the algorithm for an unweighted and undirected network,a better synchronizability of network with the same number of nodes and edges can be obtained. Numerical simulations on several different network models are used to support the proposed procedure.The relationship between different topological properties of the networks and the number of rewirings are shown.It finds that the final optimized network is independent of the initial network,and becomes homogeneous.In addition the optimized networks have similar structural properties in the sense of degree,and node and edge betweenness centralities.However,they do not have similar cluster coefficients for typeⅡnetworks.The research may be useful for designing more synchronizable networks and understanding the synchronization behaviour of networks.     

纳米光催化杀菌技术及空气净化技术研究

本文从纳米TiO2光催化杀菌及空气净化基本原理出发,对纳米光催化杀菌、杀病毒特性及污染物降解特性进 行了详细的理论分析和实验研究,结果发现纳米TiO2对细菌、病毒有很好的杀灭作用,对污染物有很好降解效果。     

A New LC–MS–MS Method for Quantitative Analysis of Adefovir,and Its Use for Pharmacokinetic Studies in Healthy Chinese Volunteers

A rapid and sensitive liquid chromatographic–tandem mass spectrometric method for analysis of adefovir in human plasma has been developed and validated. After protein precipitation and evaporation, 10 μL supernatant was injected for reversed-phase LC separation. Adefovir and the internal standard (acyclovir) were monitored in selected reaction monitoring (SRM) mode at m/z 274.10 → 256.00 and 226.10 → 152.00, respectively. The calibration plot was linear over the concentration range 0.5–100 ng mL^?1, and correlation coefficients were >0.999. Mean intra-day and inter-day accuracy ranged from 89.43 to 93.20% and from 91.40 to 95.57%, respectively, and mean intra-day and inter-day precision was between 2.40 and 7.66% and between 5.60 and 10.47%, respectively. The method was successfully applied to a Phase I pharmacokinetic study of adefovir after oral administration of adefovir dipivoxil capsules at doses of 5, 10, and 20 mg to twenty-four healthy Chinese volunteers.     

低能质子环束流与等离子体相互作用过程的一维混合模拟研究

运用一维混合模拟方法, 研究了垂直于等离子体磁场入射的低能质子环束流与等离子体的相互作用过程. 结果显示: 由质子环束流激发的等离子体波首先经历指数式快速增长的线性阶段, 随后出现饱和、衰减和相对稳定的非线性阶段. 在线性阶段, 质子束投掷角散射使波模共振作用迅速减弱, 波的增长很快出现饱和. 随后, 持续的投掷角散射, 使入射质子在速度空间从环状分布渐变为均匀分布, 同时初始阶段的右手共振不稳定性逐渐消失, 在最后相对稳定阶段只存在阿尔芬波. 研究发现, 背景等离子体的有效加热始于非线性阶段, 等离子体波的形成有助于将质子束动能转换为背景等离子体的热能.     

基于局域共振单元实现声子晶体低频多通道滤波

从理论上提出一种由局域共振单元组成的声子晶体低频多通道滤波模型.在二维三组元局域共振声子晶体中引入不同填充率的共振单元构成波导结构,通过有限元法计算出其能带结构、透射曲线和透射场图.结果显示:这种设计能够在低频带隙范围内不同填充率散射体的共振频率附近产生新的分立模,且这些分立模能够使相应的声波在声子晶体中沿波导方向传播;这些分立模只与相应的共振单元相关,抗干扰能力强.所得结果为低频多通道滤波器的设计提供了一种新的理论依据.