Interfacial passivation mechanism of sulfide towards quantum dot-sensitized nanocrystalline thin films

Journal of Solid State Electrochemistry - We report on the interfacial passivation mechanism in CdSe quantum dot-sensitized ZnO nanocrystalline thin film, where different sulfide semiconductors...     

早期干预对极低出生体重早产儿智能发育的影响研究

目的 探讨早期干预对极低出生体重早产儿智能发育的影响,为极低出生体重早产儿的早期干预提供依据。方法 239 例极低出生体重早产儿为早产随访组,采用鲍秀兰早期教育资料制定的干预计划,进行系统干预,并与326 例失访的早产儿童以及与随访组相似的326 例正常儿童进行对照分析。采用Gesell 儿童发育量表等标准化工具进行发育评估。结果 早产随访组Gesell 儿童发育量表5 项均分、总发育商（developmental quotient,DQ）总分与早产失访组相比差异均有统计学差异（均P＜0.05）。结论 早期干预能显著促进极低出生体重早产儿的智能发育,提高患儿的生活质量。     

Interpolation of Morrey-Campanato and related smoothness spaces

We study the interpolation of Morrey-Campanato spaces and some smoothness spaces based on Morrey spaces, e. g., Besov-type and Triebel-Lizorkin-type spaces. Various interpolation methods, including the complex method, the ±-method and the Peetre-Gagliardo method, are studied in such a framework. Special emphasis is given to the quasi-Banach case and to the interpolation property.     

Studies on the Thermodynamic and Kinetic Properties of the Reactions of Ti+ with Sulfur Transfer Reagent SCO Along the C═S Bond Activation Branch at 200–1200K

Theoretical studies on the thermodynamic and kinetic properties of the reactions of Ti⁺ with sulfur transfer reagent SCO via the C═S bond activation pathway have been carried on using DFT/B3LYP method, general statistical thermodynamics, and Eyring transition state theory with Wigner correction. The relevant reactions include reaction 1 ⁴ Ti⁺+¹SCO → ⁴ IM ₁ → ⁴ TS ₁ → ⁴ IM ₂ → ⁴ TiS⁺+ ¹ CO, and reaction 2 ⁴Ti⁺+¹SCO →⁴IM₁→ CP →²IM₂→²TiS⁺+¹CO in which the spin multiplicity changes from the quartet state to the doublet state in the crossing region. It is concluded that the increase of the temperature is favored to the reaction 1 process, since the equilibrium constants (K) rises from 0.566 × 10[P]-9 at 200 K to 0.109 × 10⁰ at 1200 K, and the reaction rate constant (k) from 0.222 × 10⁰ s[P]-1 at 200 K to 0.540 × 10 ¹¹ s[P]-1 at 1200 K. Moreover, reaction 1 is endothermic, and non-spontaneous in the way the entropy increases, while reaction 2 is exothermic and spontaneous in the way their entropy decreases. The reaction path 2 is the energetically favorable channel, and its thermodynamic data change not largely with the rise of temperature.     

Stereoselective Synthesis of Phosphorus Analogs of (R)-Carnitine and (R)-Gabob

Bioreduction of 3-substituted-2-oxoalkanephosphonates by baker's yeast afforded corresponding 2-hydroxy-alkanephosphonates in good yields and ee value. These compounds ( 2a,b ) could serve as useful chirons for the stereoselective synthesis of phosphorus analogs of (R)-Carnitine and (R)-GABOB.     

Bivalent Organophosphorus Compounds—Synthesis and Acetylcholinesterase Inhibitory Activity

Abstract

A series of novel symmetric S,S′-2,2′-(ethane-1,2-diylbis(azanediyl)) bis(2-oxoethane-2,1-diyl) O,O,O′,O′-tetraethyl diphosphorodithioate derivatives (12) was designed and synthesized based on the cluster effect and the multiple binding sites of acetylcholinesterase (AChE). The structures of all the newly synthesized title compounds were characterized by ¹ Choi, S. K. Synthetic Multivalent Molecules: Concepts and Biomedical Application, 20–21. New Jersey: John Wiley & Sons, Inc. 2004, chapter 1 [Google Scholar]H and ¹³ Tang, H., Zhao, L. Z., Zhao, H. T., Huang, S. L., Zhong, S. M., Qin, J. K., Chen, Z. F., Huang, Z. S. and Liang, H. 2011. Euro. J. Med. Chem., 46: 4970–4979. [Crossref], [PubMed], [Web of Science ®] , [Google Scholar]C NMR as well as elemental analyses. Their inhibitory activities against AChE were tested, and compound 12b exhibited the best activity (6.60-fold higher than ethion). The results suggested that the compound would bind to the catalytic center and the narrow gorge of the AChE simultaneously.

Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfer, and Silicon and the Related Elements for the following free supplemental files: Additional table.     

Catalytic activity of chiral chelating N-heterocyclic carbene palladium complexes towards asymmetric allylic alkylation

Abstract

The catalytic activity of a series of chiral heteroaryl coordinated chelating N-heterocyclic carbene (NHC) palladium complexes towards asymmetric allylic alkylation (AAA) were presented here. The effects of different N-substituents, NHC backbones and chelate rings on the catalytic activity and the enantioselectivity of the alkylation of (E)-1,3-diarylallyl acetates with dialkyl malonate were investigated. The results showed that, under the optimized conditions, complexes 3a, 3b, and 3i carrying the pyridinyl-coordinated five-membered chelate ring showed high catalytic activity and chiral induction efficiency. The corresponding alkylated products were obtained in high yields with moderate ee. Furthermore, it was found that the substituents of (E)-1,3-diarylallyl acetates and the type of the nucleophile affect the results as well.     

STUDIES ON ORGANOPHOSPHORUS COMPOUNDS XLIV. STRUCTURAL EFFECT OF ELECTROPHILES ON THE REGIOSELECTIVITY OF CARBANION DERIVED FROM DIALKYL ALLYLPHOSPHONATES

Abstract

For the evaluation of the structural effect of electrophiles on the regioselectivity of ambident anions, the reaction of phosphoryl allylic carbanion with p-substituted benzaldehydes was investigated.