全文获取类型
收费全文 | 1181篇 |
免费 | 39篇 |
国内免费 | 4篇 |
专业分类
化学 | 905篇 |
晶体学 | 11篇 |
力学 | 12篇 |
数学 | 50篇 |
物理学 | 246篇 |
出版年
2022年 | 6篇 |
2021年 | 10篇 |
2020年 | 18篇 |
2019年 | 16篇 |
2018年 | 15篇 |
2017年 | 9篇 |
2016年 | 27篇 |
2015年 | 20篇 |
2014年 | 27篇 |
2013年 | 60篇 |
2012年 | 65篇 |
2011年 | 71篇 |
2010年 | 35篇 |
2009年 | 42篇 |
2008年 | 75篇 |
2007年 | 67篇 |
2006年 | 74篇 |
2005年 | 62篇 |
2004年 | 66篇 |
2003年 | 52篇 |
2002年 | 43篇 |
2001年 | 20篇 |
2000年 | 26篇 |
1999年 | 15篇 |
1998年 | 16篇 |
1997年 | 10篇 |
1996年 | 12篇 |
1995年 | 13篇 |
1994年 | 24篇 |
1993年 | 9篇 |
1992年 | 24篇 |
1991年 | 9篇 |
1990年 | 12篇 |
1989年 | 11篇 |
1988年 | 11篇 |
1986年 | 7篇 |
1985年 | 19篇 |
1984年 | 17篇 |
1983年 | 11篇 |
1982年 | 10篇 |
1981年 | 11篇 |
1980年 | 6篇 |
1979年 | 9篇 |
1978年 | 4篇 |
1977年 | 4篇 |
1976年 | 4篇 |
1974年 | 5篇 |
1973年 | 5篇 |
1972年 | 5篇 |
1970年 | 5篇 |
排序方式: 共有1224条查询结果,搜索用时 15 毫秒
51.
Masahiko Takahashi Tomoko Gunji Akiko Ichikawa 《Journal of heterocyclic chemistry》2002,39(5):1029-1033
Reactions of 1,2‐dihydro‐4H‐3,1‐benzothiazine‐2,4‐dithiones (trithioisatoic anhydrides) 3 with N‐substi‐tuted benzylamines 9 gave 1,2‐dihydroquinazoline‐4‐thiones 10 , o‐thioureidodithiobenzoic acid 11 , o‐aminothiobenzamides 12 , 2‐amino‐3,1‐benzothiazine‐4‐thiones 13 , or quinazoline‐2,4‐dithiones 14 , depending on the kinds of amine and the reaction solvent. On the other hand, reaction of 3 with trialkyl phosphites afforded dialkyl (1,2‐dihydro‐2‐thioxo‐4H‐3,1‐benzothiazin‐4‐yl)phosphonates 18 . 相似文献
52.
Tsuneki Ichikawa Ken-ichi Oyama Tatsu Kondoh Hiroshi Yoshida 《Journal of polymer science. Part A, Polymer chemistry》1994,32(13):2487-2492
Effect of irradiation temperature on the main-chain scission of poly (methyl methacrylate) (PMMA) caused by γ-irradiation was studied by means of gel permeation chromatography and ESR spectroscopy. Although no temperature dependency was observed on the scission efficiency for purified PMMA, the efficiency for crude or monomer-doped purified PMMA was decreased by decreasing the temperature below ca. 200 K. Above 200 K the efficiency was constant and did not depend on the purity of PMMA. ESR study of the irradiated PMMA revealed that the suppression of the scission below 200 K is induced by the addition of methyl methacrylate monomer to primary radical species, which otherwise cause the main-chain scission by warming the polymer above 200 K. The primary radical generated above 200 K immediately converts to the scission-type ? CH2 ? ?(CH3) COOCH3 radical through the β-scission of the polymer main chain, so that the efficiency of the scission does not depend on both the impurity and the irradiation temperature. © 1994 John Wiley & Sons, Inc. 相似文献
53.
Yoshitaka Ogiwara Yukie Ogiwara Hitoshi Kubota 《Journal of polymer science. Part A, Polymer chemistry》1967,5(11):2791-2805
Graft copolymerization of methyl methacrylate on cellulosic materials of various carbonyl and aldehyde contents with the use of a ceric salt as an initiator was studied. It was found that the concentration of the ceric salt which gives the maximum per cent grafting is in good agreement with the equivalent of total carbonyl content in the cellulosic material, and the number of grafted chains in copolymers is roughly proportional to it. However, the molar ratio of the number of grafted chains to total carbonyl content is quite small, being approximately 1:50, and the graft copolymerization can be explained kinetically on the assumption that the number of radicals produced on cellulose by the ceric salt leading to branching is very much smaller than the number of radicals destroyed by the ceric salt, and growing radicals can be stabilized by the termination reaction with the ceric salt or with a cellulose radical. Although both aldehyde and carbonyl groups contribute to the formation of grafted chains, the former are effective mainly at low concentrations of the ceric salt; both groups participate in the production of graft copolymers showing the maximum per cent grafting. 相似文献
54.
55.
Chi-Huey Wong Randall L. Halcomb Yoshitaka Ichikawa Tetsuya Kajimoto 《Angewandte Chemie (International ed. in English)》1995,34(4):412-432
Carbohydrates on cell surfaces are information molecules. Although only seven or eight monosaccharides are commonly used as building blocks in mammalian systems, the multifunctionality of these monomers can lead to the assembly of an immense variety of complex structures. Millions of different tetrasaccharide structures, for example, can be constructed from this small number of building blocks, if branching, the stereochemistry of glycosidic linkages, and the modification of hydroxyl and amino groups are taken into consideration. Oligosaccharides therefore represent an effective class of biomolecules that code for a vast amount of information required in various biological recognition processes, such as intercellular communication, signal transduction, cell adhesion, infection, cell differentiation, development and metastasis. The pace of development of pharmaceuticals based on carbohydrates has, however, been slower than that based on other classes of biomolecules. Part of the reason is the lack of technologies for the study of complex carbohydrates. There is no method to amplify oligosaccharides for sequence analysis. There is no machine available for automated synthesis of oligosaccharides. In addition, the possibly poor bioavailability and difficulties in the large-scale synthesis of carbohydrates have undoubtedly contributed to this slow pace. The enzymatic and chemoenzymatic methods, especially those based on aldolases and glycosyltransferases, described here appear to be useful for the synthesis of mono- and oligosaccaharides and related molecules. Further advances in glycobiology will probably lead to the development of new technologies for the study of carbohydrate recognition and for the synthesis of bioactive carbohydrates and mimetics to control the recognition processes. 相似文献
56.
Wickramasinghe NP Shaibat M Ishii Y 《Journal of the American Chemical Society》2005,127(16):5796-5797
High-resolution NMR spectroscopy for paramagnetic complexes in solids has been rarely performed because of its limited sensitivity and resolution due to large paramagnetic shifts and associated technical difficulties. The present study demonstrates that magic angle spinning (MAS) at speeds exceeding 20 kHz provides unusually high sensitivity and excellent resolution in 1H solid-state NMR (SSNMR) for paramagnetic systems. Spinning-speed dependence of 1H MAS spectra showed that very fast MAS (VFMAS) at 24-28 kHz enhanced sensitivity by a factor of 12-18, compared with the sensitivity of 1H SSNMR spectra under moderate MAS at 10 kHz, for Cu(dl-alanine)2.H2O and Mn(acac)3, for which the spectral ranges due to 1H paramagnetic shifts reach 200 and 1000 ppm, respectively. It was theoretically and experimentally confirmed that the absolute sensitivity of 1H VFMAS for small paramagnetic complexes such as Cu(dl-alanine)2 can be an order of magnitude higher than that of equimolar diamagnetic ligands because of short 1H T1 ( approximately 1 ms) of the paramagnetic systems and improved sensitivity under VFMAS. On the basis of this demonstrated high sensitivity, 1H SSNMR micro analysis of paramagnetic systems in a nanomole scale is proposed. Applications were performed on two polymorphs of Cu(II)(8-quinolinol)2, which is a suppressor of human cancer cells. It was demonstrated that 1H VFMAS SSNMR spectra accumulated for 20 nmol of the polycrystalline samples in 10 min enabled one to distinguish alpha- and beta-forms of Cu(II)(8-quinolinol)2 on the basis of shift positions and line widths. 相似文献
57.
Hitoshi Kubota Yoshitaka Ogiwara Kei Matsuzaki 《Journal of polymer science. Part A, Polymer chemistry》1974,12(12):2809-2819
The decay behavior of cellulose radicals produced by photo-irradiation at room temperature and the characteristics of photo-irradiated cellulose samples to initiate graft copolymerization of methyl methacrylate (MMA) were investigated. ESR spectra of such untreated, swollen, oximated, and ferric ion-sensitized samples irradiated at room temperature were constructed mainly of a single absorption line with a line width of 20 to 22 gauss and a g value of 2.003, and it is surely conceivable that the radicals showing a singlet spectrum should agree with those of alkoxy end produced at either the C1 or C4 position of the glucose unit by the scission of glucosidic bonds. The decay of radicals was accelerated by contact of various solvents with the samples, the activity decreasing in the order, water ≈ methanol ? acetone > dioxane. On the other hand, the decay of radicals by vinyl monomers became smaller in the order, methacrylic acid > MMA ≈ styrene. Graft copolymerization of MMA by a photo-irradiated sample was effectively initiated with the use of a certain amount of water or methanol, but not with acetone and dioxane. As no initiation can occur with the unirradiated sample, it is concluded that the initiation of graft copolymerization on the photo-irradiated sample is attributable to cellulose radicals showing a singlet spectrum which are formed in photo-irradiation at room temperature. 相似文献
58.
Yuka Wakata Mika Tokumoto Ryo Horiguchi Katsutoshi Ishikawa Yoshitaka Nagahama Toshinobu Tokumoto 《BMC biochemistry》2004,5(1):18
Background
The 26S proteasome is the proteolytic machinery of the ubiquitin-dependent proteolytic system responsible for most of the regulated intracellular protein degradation in eukaryotic cells. Previously, we demonstrated meiotic cell cycle dependent phosphorylation of α4 subunit of the 26S proteasome. In this study, we analyzed the changes in the spotting pattern separated by 2-D gel electrophoresis of α subunits during Xenopus oocyte maturation. 相似文献59.
Yoshitaka Ishimuro Fumiyuki Hamada Akio Nakajima 《Journal of polymer science. Part A, Polymer chemistry》1979,17(6):1811-1819
The scattering function of rods with a constant radius, 8 Å, and a length distribution of the Schulz–Zimm type was calculated on a computer as a model of helical synthetic polypeptide. The influence of length and length distribution on the scattered intensity of small-angle x-ray scattering was clarified. As length grows and length distribution broadens it is difficult to obtain reliable values of molecular weight and radius of gyration from a Zimm plot. The influence of length distribution on the mass per unit length, Mq, and the radius of gyration of the cross section, 〈S〉1/2, from the Guinier plot of the cross-sectional factor decreases as the length increases, and reliable values of Mq and 〈S〉1/2 can be obtained even for rods with wide distribution for rods more than 600 Å long. In particular, it is pointed out that the value of 〈S〉1/2 is little influenced by length and length distribution. 相似文献
60.
Hino S Ichikawa T Ogita N Udagawa M Fujii H 《Chemical communications (Cambridge, England)》2005,(24):3038-3040
The partial pressure of NH3 gas estimated by Raman spectroscopy indicates that approximately 0.1% NH3 inevitably contaminates the H2 desorbed from a hydrogen storage material composed of LiH and LiNH2 at any temperature up to 400 degrees C in a closed system. 相似文献