2型糖尿病患者血清钙镁与甲状腺激素含量变化及临床意义

为了监测 2型糖尿病人血清钙、镁和甲状腺激素含量 ,分析其临床意义及相关性 ,应用放射免疫分析法测定了 1 1 5例 2型糖尿病及 1 5 0例健康人血清甲状腺激素含量。同时用美国杜邦RXL自动生化仪测定了其血清钙、镁含量。结果表明 ,在 2型糖尿病伴有明显并发症者血镁、FT3水平明显降低 (P <0 0 5 ) ,钙镁两种元素与甲状腺激素水平无明显相关性。 2型糖尿病患者适当补镁对预防其并发症是有益的 ,测定FT3 等可作为判断 2型糖尿病严重程度和估计预后的参考指标。     

Calculation of avoided crossings for highly excited Stark states of Rb

Using the method of diagonalization, in which zero-field wavefunctions from a potential model are chosen as a basis, we calculate positions and widths of anticrossings for highly excited Stark states of Rb with principal quantum number n up to 49. We obtain the theoretical positions and widths in good agreement with available experimental values, and we present scaling laws of the field positions and widths of anticrossings that can be used to provide information for future experiments.     

Water-soluble oligomer dimers based on paracyclophane: a new optical platform for fluorescent sensor applications

Water soluble paracyclophane chromophore dimers provide optical reporters that show little sensitivity to surfactants and thus are ideal for biosensor design. Strong intramolecular delocalization circumvents complications from intermolecular delocalization in spontaneously formed aggregates. The synthesis of 2 involves a novel TBAT deprotection/butane sultone ring-opening sequence, which should be general for the preparation of water-soluble conjugated oligomers and polymers.     

Dye-sensitized solar cells based on composite solid polymer electrolytes

The ionic conductivity of polymer electrolytes and their interfacial contact with dye-attached TiO2 particles were enhanced markedly by the addition of amorphous oligomer into polymer electrolytes, resulting in very high overall energy conversion efficiency.     

An addition to the oxoacid family: H2B12(OH)12

The acid H(2)B(12)(OH)(12) can be isolated as a crystalline solid by protonation of the hydroxylated borane anion, B(12)(OH)(12)(2)(-). This acidic compound has low solubility in water, conducts protons in the solid state, and has thermal stability to a temperature of 400 degrees C. The conductivity mechanism is a Grotthuss mechanism with a low activation enthalpy (9-13 kcal/mol). This new acid represents an addition to the class of oxoacids, of which sulfuric and phosphoric acid are the most prominent examples.     

ortho Substituent effect on a 1,5-H shift reaction during thermal decomposition of aryltriazenes

An ortho substituent group has a significant effect on thermal decomposition of aryltriazenes. When the ortho methoxy-substituted phenyltriazenes were treated with methyl iodide at 110-130 °C, 1,5-H shift products were obtained in fair to moderate yields.     

Unlabeled Fluoroimmunoassay with a Europium Chelate

Unlabeled fluoroimmunoassay with a europium chelate is described. The recommended method is simple because the complicated labeling process is omitted. The recovery of some samples ranges from 91 to 111%. The relative standard deviation of the method is less than 10%. The detection limit is about 10⁻¹⁰mol liter⁻¹antigen.     

Cyclization reactions of N-acryloyl-2-aminobenzaldehyde derivatives: formal total synthesis of martinellic acid

N-Alkyl acryloylamides derived from o-aminobenzaldehyde derivatives react with N-alkyl glycine derivatives to provide cis-fused pyrrole[3,2-c]quinolones in moderate yield and high diastereoselectivity. These same substrates engage in a tandem Michael-Mannich pathway on treatment with a secondary amine, providing corresponding quinolone derivatives. The elaboration of a pyrroloquinolone derivative via addition of an in situ generated functionalized copper acetylide to an in situ generated iminium ion provided the C2-substituted derivative. Global deprotection and reduction of the alkyne afford the tricyclic triamine core (as the HCl salt) found in martinellic acid.     

Quantum chemical study on the mechanism of the consecutive addition of HCN to aminoacetonitrile

MINDO/3 method has been used to study the mechanism of the consecutive addition ofHCN to aminoacetonitrile.The results obtained for the first three steps show that the reaction isexothermic,and step I is the rate determining step.