Background
Although a large body of knowledge about both brain structure and function has been gathered over the last decades, we still have a poor understanding of their exact relationship. Graph theory provides a method to study the relation between network structure and function, and its application to neuroscientific data is an emerging research field. We investigated topological changes in large-scale functional brain networks in patients with Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) by means of graph theoretical analysis of resting-state EEG recordings. EEGs of 20 patients with mild to moderate AD, 15 FTLD patients, and 23 non-demented individuals were recorded in an eyes-closed resting-state. The synchronization likelihood (SL), a measure of functional connectivity, was calculated for each sensor pair in 0.5–4 Hz, 4–8 Hz, 8–10 Hz, 10–13 Hz, 13–30 Hz and 30–45 Hz frequency bands. The resulting connectivity matrices were converted to unweighted graphs, whose structure was characterized with several measures: mean clustering coefficient (local connectivity), characteristic path length (global connectivity) and degree correlation (network 'assortativity'). All results were normalized for network size and compared with random control networks. 相似文献This work deals with the dynamics of a network of piezoelectric micro-beams (a stack of disks). The complete synchronization condition for this class of chaotic nonlinear electromechanical system with nearest-neighbor diffusive coupling is studied. The nonlinearities within the devices studied here are in both the electrical and mechanical components. The investigation is made for the case of a large number of coupled discrete piezoelectric disks. The problem of chaos synchronization is described and converted into the analysis of the stability of the system via its differential equations. We show that the complete synchronization of N identical coupled nonlinear chaotic systems having shift invariant coupling schemes can be calculated from the synchronization of two of them. According to analytical, semi-analytical predictions and numerical calculations, the transition boundaries for chaos synchronization state in the coupled system are determined as a function of the increasing number of oscillators.
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