Catalytic enantioselective aryl transfer to aldehydes using chiral 2,2'-bispyrrolidine-based salan ligands

Chiral C?-symmetric diamines have emerged as versatile auxiliaries or ligands in numerous asymmetric transformations. Chiral 2,2'-bispyrrolidine-based salan ligands were prepared and applied to the asymmetric aryl transfer to aldehydes with arylboronic acids as the source of transferable aryl groups. The corresponding diarylmethanols were obtained in high yields with moderate to good enantioselectivitives of up to 83% ee.     

L-Proline promoted fluorescent sensor for Mg2+ detection in a multicomponent sensory system

Mg(2+) can lead to the fluorescence enhancement of a dye molecule as high as 47.3-fold while L-proline acts as a promoter in this multicomponent sensory system. The fluorescence color could be easily detected by the naked eye under a UV-lamp.     

基于1,1'-联-2-萘酚衍生物的手性荧光传感器

具有光活性的1,1′-联-2-萘酚（BINOL）衍生物是近年来研究较多的C2轴不对称芳香化合物,不仅具有很强的手性诱导作用,而且在适合结构基团修饰下能产生很强的荧光,可作为一类有效而灵敏的荧光化学传感器。在与手性胺、氨基醇、氨基酸、α-羟基羧酸、手性醇和单糖等手性有机化合物作用时,该荧光化学传感器在不同识别位点接受客体分子、通过光诱导电子转移（PET）及电子交换能量转移（EET）等引起共轭高分子内能级发生变化,使得所有这些相互作用十分灵敏地在其发光强度和能量上反映出来,具体表现在化学传感器荧光增强与减弱或发射波长的变化上。本文总结了近年来1,1′-联-2-萘酚衍生物的荧光化学传感器在手性异构体识别领域的最新研究进展。     

The design and synthesis of β‐trifluoromethylenol phosphates as potential insecticides

A new group of compounds, β‐trifluoromethylenol phosphates [(RO)₂P(O)OCRCHCF₃], has been designed and prepared by several methods. Some of them showed good insecticidal activities. In the molecular structure, the designed leaving group can rearrange to a powerful electrophilic agent, β,β‐difluorovinyl ketone, which would be a potential enzyme inhibitor. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:304–308, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10147