磁绝缘传输线实验用电阻分压器型大功率负载设计

研制了一种用于磁绝缘传输线（MITL）实验的分压器型大功率水电阻负载,其阻值可在2.0~14.0 变化。利用MATLAB系统辨识工具箱和ANSYS电磁分析模块,分别获取了分压器的系统传递函数和沿面电场分布,给出了其幅频响应特性和沿面闪络可靠性分析,负载设计充分考虑了集肤效应和温升的影响。该负载已用于强光一号1.0 m长MITL特性研究实验,并获得了较好的测量波形,在负载阻值2.1 条件下,负载峰值电压为1.2 MV,峰值电流为494.4 kA,峰值时间约125 ns。将实验测量结果同TLCODE计算结果进行了对比,获得了较为一致的对比结果。     

磁绝缘传输线电流测量差模式B-dot探头

研制了一种用于磁绝缘传输线（MITL）电流测量的差模式B-dot探头;利用PSpice商用软件和标定实验数据,建立了该探头等效电路模型,给出了探头系统传递函数,并分析了探头频率响应特性。计算结果表明,该探头对于被测信号大于2.5 MHz频率分量部分的相频响应基本保持不变,而幅频响应曲线呈较好的直线性。该探头已用于强光一号1.0 m长、2 cm阴阳极间隙的同轴型MITL电流传输特性研究实验,并获得了较好的测量波形。测量结果表明:短路负载条件下,传输线沿线不同位置B-dot 电流测量结果基本相同,峰值电流约1.0 MA、峰值时间约125 ns。即传输线沿线电流损失几乎可以忽略,该实验结果与短路负载MITL工作特性理论较好地吻合。     

Apoptosis induced by sonodynamic treatment by protoporphyrin IX on MDA-MB-231 cells

Sonodynamic therapy (SDT) is a promising modality for cancer treatment, involving the synergistic interaction of ultrasound and some chemical compounds termed as sono-sensitizers. It has been found that SDT can lead to apoptotic cell death because of the induction of direct sonochemical and subsequent redox reactions. However, the detailed mechanisms are not clear. This study was to identify the cytotoxic effects of ultrasound-activated protoporphyrin IX (PpIX) on MDA-MB-231 cells. The fluorescence microscope was used to detect the sub-cellular localization of PpIX. Several distinct sonochemical effects were found after SDT treatment, including the decrease of cell viability, generation of intracellular ROS, the loss of mitochondrial membrane potential. The activation of some special apoptosis-associated proteins [Caspase-9, Caspase-3 and polypeptide poly (ADP-robose) polymerase] was evaluated by western blotting. The results show that PpIX mediated SDT (PpIX-SDT) treatment could obviously inhibit the proliferation of MDA-MB-231 cells, and which was significantly reduced by the pan-Caspase inhibitor z-VAD-fmk and the reactive oxygen species (ROS) scavenger N-acetylcysteine (NAC). Further, SDT induced a conspicuous loss of mitochondrial membrane potential (MMP) and a mass of ROS accumulation in MDA-MB-231 cells at 1 h post-treatment and the SDT-treated cells showed obvious Caspase-3 and Caspase-9 activation, and PARP cleavage at 6 h after treatment. And, the general apoptosis marker-Caspase-3 activation-was also greatly relieved by NAC. These findings primarily indicate a Caspase-depended apoptosis could be induced by PpIX-SDT in MDA-MB-231 cells, and the intracellular ROS was involved during the apoptotic process.     

Exact explicit traveling wave solutions for two nonlinear Schrödinger type equations

The traveling wave solutions of the generalized nonlinear derivative Schrödinger equation and the high-order dispersive nonlinear Schrödinger equation are studied by using the approach of dynamical systems and the theory of bifurcations. With the aid of Maple, all bifurcations and phase portraits in the parametric space are obtained. All possible explicit parametric representations of the bounded traveling wave solutions (solitary wave solutions, kink and anti-kink wave solutions and periodic wave solutions) are given.     

A helical chiral polymer‐based chromo‐fluorescence and CD response sensor for selective detection of trivalent cations

A novel chiral (S)‐BINAM‐based fluorescent polymer sensor was designed and synthesized by the polymerization of 4,4′‐((2,5‐dibutoxy‐1,4‐phenylene)bis(ethyne‐2,1‐diyl))‐dibenzaldehyde ( M‐1 ) with (S)‐2,2′‐binaphthyldiamine (S‐BINAM, M‐2 ) via Schiff's base formation. The resulting helical chiral polymer sensor exhibited remarkable “turn‐on” bright blue fluorescence color upon the addition of trivalent metal ions under a commercially available UV lamp; this change can be clearly observed by the naked eye for direct visual discrimination at low concentration. More importantly, the addition of trivalent metal cations can lead to a most pronounced change of CD spectra of the chiral polymer indicating this kind chiral sensor can also be used as a sole probe for selective recognition of trivalent metal cations based on CD spectra. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013 , 51, 4070–4075     

Circularly Polarized Luminescence of Chiral Perylene Diimide Based Enantiomers Triggered by Supramolecular Self‐Assembly

Two perylene diimide (PDI) enantiomers ( d/l ‐PDI ) incorporating the d /l ‐alanine moiety have been designed and synthesized. d/l ‐PDI in chloroform displays bright‐yellow fluorescence that is redshifted to orange‐red when the solvent contains a methanol fraction of 99 vol %. No circular dichroism (CD) or circularly polarized luminescence (CPL) signals were observed for d/l ‐PDI enantiomers in CHCl₃. Interestingly, the d/l ‐PDI enantiomers exhibit clear mirror‐image Cotton effects and CPL emission in the aggregate state. The optical anisotropy factor (g_lum) is as high as 0.02 at f_m=99 %, which can be attributed to self‐assembly through intermolecular π–π interactions in the aggregate state.     

Effects of Air/H<Subscript>2</Subscript>O Discharge Plasma on Propane Combustion Enhancement Using Dielectric Barrier Discharges

Combustion provides about 80% energy for our daily life and industrial production. But thermal efficiency of traditional combustion technologies is low, which causes energy waste and serious environmental pollution. In order to improve the combustion efficiency, a combined method based on non-equilibrium plasma generated by dielectric barrier discharge and OH radicals coming from water-steam additive was proposed in this work, and plasma assisted propane combustion was examined and evaluated. The results indicated that when relative humidity (RH) was 20% and applied peak voltage was fixed at 8.75 kV, the relative intensity of OH radical and the flame temperature reached the maximum value at the flame root. At the same time, propane combustion was the most complete. In addition, we found that the erosion of the inner electrode was weakened by H₂O addition, and the symmetry of discharge current was changed from symmetry to asymmetry with the increase of RH. Compared with the pure air undischarged combustion, when the relative humidity was 20% and under the discharge conditions of 8.75 kV, the lean-burn extinction limit was extended to 0.4,which is far lower than the traditional lean-burn limit (0.51).     

Gold-catalyzed cascade C–C and C–N bond formation: synthesis of polysubstituted indolequinones and pyrroles

The combination of Ph₃PAuCl and AgOTf was proven to be an efficient catalyst for the cascade C–C and C–N bond formation reactions from enamines and bromoquinones or nitroolefins. This protocol affords a straightforward method for the synthesis of polysubstituted indolequinones and pyrroles in good yields.     

A New Chiral Binaphthalene‐Based Fluorescence Polymer Sensor for the Highly Enantioselective Recognition of Phenylalaninol

A new (S)‐binaphthalene‐based polymer ( P ‐ 1 ) was synthesized by the polymerization of 5,5′‐((2,5‐dibutoxy‐1,4‐phenylene)bis(ethyne‐2,1‐diyl))bis(2‐hydroxy‐3‐(piperidin‐1‐ylmethyl) benzaldehyde ( M ‐ 1 ) with (S)‐2,2′‐dimethoxy‐(1,1′‐binaphthalene)‐3,3′‐diamine ( M ‐ 2 ) through the formation of a Schiff base; the corresponding chiral polymer ( P ‐ 2 ) could be obtained by the reduction of polymer P ‐ 1 with NaBH₄. Chiral polymer P ‐ 1 exhibited a remarkable “turn‐on” fluorescence‐enhancement response towards (D )‐phenylalaninol and excellent enantioselective recognition behavior with enantiomeric fluorescence difference ratios (ef) as high as 8.99. More importantly, chiral polymer P ‐ 1 displays a bright blue fluorescence color change upon the addition of (D )‐phenylalaninol under a commercially available UV lamp, which can be clearly observed by the naked eye. On the contrary, chiral polymer P ‐ 2 showed weaker enantioselective fluorescence ability towards the enantiomers of phenylalaninol.