排序方式: 共有131条查询结果,搜索用时 0 毫秒
131.
Yi-Tao Sun Dr. Chun Zhang Li-Xin Gao Min-Min Liu Yuting Yang Dr. Andong Shao Prof. Dr. Yu-Bo Zhou Dr. Yun-Long Zhu Prof. Dr. Jia Li Prof. Dr. Wen-Long Wang 《Chemphyschem》2023,24(17):e202300159
Fluorescence imaging is conducive to establish a bridge between molecular biology and clinical medicine, and provides new tools for disease process research, early diagnosis, and efficacy evaluation, because of the advantages of rapid imaging and nondestructive detection. Herein, a series of fluorescent molecules with thiadiazole, or thiazole, or benzothiazole cores were designed and synthesized to develop more excellent fluorescent molecules in bio-imaging. According to theoretical and experimental methods, we found that benzothiazole derivative 14 B with conjugate expansion by (4-aminophenyl) ethynyl group was the most excellent fluorescent molecule among all the investigated compounds and exhibited low cytotoxicity and strong blue and green fluorescence by confocal cell imaging. 相似文献