Targeting Upconversion Nanoprobes for Magnetic Resonance Imaging of Early Colon Cancer

Colon cancer (CC) is one of the most common intestinal malignancies and is difficult to detect in its early stage by magnetic resonance imaging (MRI) with currently used contrast agents (CAs). The development of targeted CAs contributes to the early diagnosis of CC and thereby enables early intervention and timely therapy. Considering the outstanding performance of upconversion nanoprobes (UCNPs) in high‐performance MR and fluorescence imaging, a new type of nanoprobes with considerably enhanced imaging performance is developed herein. Carcinoembryonic antigen (CEA) antibody is conjugated onto the surface of UCNPs to achieve the targeted imaging of early CC tumors, which overexpress CEA. Both toxicity tests and histological/hematological examinations demonstrate the excellent biocompatibility of these CC‐targeting nanoprobes, which possess great potential for clinical application in the early diagnosis of CC.     

Proton beam writing of Nd:GGG crystals as new waveguide laser sources

Focused proton beam writing has been utilized to fabricate optical channel waveguides in Nd:GGG crystals. The 1?MeV proton beam irradiation creates a local modified region with positive refractive index changes at the end of the proton trajectory, in which the channel waveguide could confine the light field in a symmetric way. Room-temperature laser emission has been achieved at 1063.7?nm, with absorbed pump power of 61?mW (at 808?nm). The obtained slope efficiency of the Nd:GGG waveguide laser system is as high as 66%, which is, to our best knowledge, the highest value for integrated lasers from ion beam processed channel waveguide systems.     

R值测量中强子事例选择的改进

强子事例的选择和强子探测效率是在BEPC/BES上进行R值测量的两项主要误差来源. 过去实验只选取等于或者大于2叉的强子事例, 因而0叉和1叉事例的丢失将导致强子事例数和强子探测效率的较大误差. 试图提出在R值测量中选取包含1叉强子事例在内的样本, 这将有助于更合理地调节强子事例产生器LUARLW的参数, 减小强子探测效率和R值测量的系统误差.     

原始数据中束流相关本底的分离

束流相关本底处理的不确定性是在BES/BEPC上进行R值测量的主要误差来源之一,提出从原始数据中分离出束流相关样本的新方法, 并把此样本用于调节强子产生器LUARLW的参数,以减小强子探测效率的系统误差, 提高R值的测量精度.     

LD-end-pumped 60 pm linewidth Tm:YLF laser

Narrow linewidth continuous-wave Tm:YLF laser at room temperature with a Volume Bragg grating and double Fabry-Perot etalons by using the end-pumping configuration was presented. The Tm:YLF laser operates at 1907.3 nm with FWHM of approximately 60 pm. We achieved the maximum output power of 1.92 W when the incident pump power of 13.9 W, corresponding to the optical-to-optical conversion efficiency of 13.8% and slope efficiency of 16.4%.     

High-efficiency resonantly pumped room temperature Ho:YVO4 laser

An efficient 2 μm room temperature Ho:YVO(4) laser resonantly pumped by a 1.94 μm Tm:YAP laser is demonstrated, for the first time to our knowledge, in this Letter. Up to 8.58 W of laser output at 2053 nm is obtained with the optical-to-optical conversion efficiency as much as 41.2%. The output beam had quality of M² factor with Mx(2) of 3.58 and My(2) of 1.76 at 8 W output level. In addition, we also obtained 4.18 W laser output at 2066 nm and 7.04 W at 2040 nm from the Ho:YVO(4) laser with conversion efficiency of 27.8% and 33.8%, respectively.     

间接原子吸收光谱法测定水样中的痕量硼

本文研究了四氟硼酸根与邻二氮菲银形成的络合物由MIBK萃取后,用火焰原子吸收光谱法间接测定硼,其线性范围为0.002-1μg/mL,检出限为0.41μg/mL,回收率为93%-101%,且K^ 、Na^ 等10个种离子不干扰测定,本方法用于地下水中痕量硼的测定,结果令人满意。     

一种新型二维X射线探测器

本文建立一种新型X射线探测器,它是一种矩阵寻址方式的二维探测器,由两块玻璃基板组成,分别称作阴极板和阳极板,阴极板内侧镀有行电极和X射线阴级（例如CsI),阳极板上有寻址电极,障壁,两块基板对位封接,使行电要与寻址电极互相垂直,封接后先抽高真空,然后充入氩气与CO2混合气体,本探测器具有薄,轻,图象无畸变并可以利用PDP显示器件的工艺制作大尺寸器件及大量制造等优点。