Fractal Analysis of Transport Properties in a Sinai Billiard

Research contacting chaos with fractals is carried out.First,we employ the theoretical quarter Sinai billiard model to study its chaos by using the stationary e...     

Synthesis and Properties of SEPS-<Emphasis Type=Italic>g</Emphasis>-PEO Copolymers with Varying Branch Lengths

Poly(ethylene oxide) (PEO) was controllably grafted from styrene-b-(ethylene-co-propylene)-b-styrene (SEPS) backbones by combining lithiation of styrenic units and living monomer-activated anionic ring-opening polymerization of ethylene oxide (EO)monomers with the aid of co-initiators triisobutyl aluminum.The as-synthesized SEPS-g-PEO copolymers were characterized by SEC,1H-NMR,FTIR,SAXS,AFM and DSC.When the branch length is relatively small,increase of PEO fraction leads to the increase of the correlation length between neighboring hard domains,but the degree of correlation reduces.When the branch length is relatively large,the phase-separated structures become random both in terms of size and spatial correlation,and macro-phase separated structures appear.The crystallization behavior of the PEO branches can be effectively inhibited in SEPS-g-PEO,so no significant crystallization takes place until the fraction of PEO branches is 20.1 wt％,which greatly promotes the rapid delivery of hydrophilic drugs in the hot-melting pressuresensitive adhesives (HMPSAs) based on SEPS-g-PEO.Their cumulative release amount of a model drug could achieve 80％,more than twice the value in the HMPSAs based on linear PEO-containing styrenic block copolymers.     

Y2O3-Eu2O3-SnO2三元系固相线下相关系及其发光性质研究

采用固态反应法及改良固态反应法合成了一系列Y₂O₃-Eu₂O₃-SnO₂体系中的试样，利用X射线粉末衍射法测定了Y₂O₃-Eu₂O₃-SnO₂三元系固相线下的相关系.结果表明，Y₂O₃-Eu₂O₃二元系 关键词： 2O₃-Eu₂O₃-SnO₂三元系')" href="#">Y₂O₃-Eu₂O₃-SnO₂三元系 烧绿石型结构 激发光谱 发射光谱     

利用锁相环和TV-Rb钟控制飞秒激光脉冲的载波包络相移

为了实现对锁模飞秒钛宝石激光器的相位控制，采用改进的相移测量装置，使载波包络频移信号的信噪比提高到了40 dB以上.在此优化测量结果的基础上，利用电子锁相环技术，通过PZT改变激光器腔内端镜的倾斜将飞秒激光脉冲的载波包络相位锁定到了微波参考源TV-Rb钟10 MHz标准信号上，同时激光脉冲重复频率也采用另一个PZT控制激光腔长锁定到了同一个TV-Rb钟10 MHz信号上.锁定后的结果显示重复频率的锁定达到了TV-Rb钟本身的稳定度，而载波包络相位锁定后比锁定前稳定度提高了三个数量级.     

The Spectral Properties of the Strongly Coupled Sturm Hamiltonian of Eventually Constant Type

We study the spectral properties of the Sturm Hamiltolian of eventually constant type, which includes the Fibonacci Hamiltonian. Let s be the Hausdorff dimension of the spectrum. For V > 20, we show that the restriction of the s-dimensional Hausdorff measure to the spectrum is a Gibbs type measure; the density of states measure is a Markov measure. Based on the fine structures of these measures, we show that both measures are exact dimensional; we obtain exact asymptotic behaviors for the optimal Hölder exponent and the Hausdorff dimension of the density of states measure and for the Hausdorff dimension of the spectrum. As a consequence, if the frequency is not silver number type, then for V big enough, we establish strict inequalities between these three spectral characteristics. We achieve them by introducing an auxiliary symbolic dynamical system and applying the thermodynamical and multifractal formalisms of almost additive potentials.     

Mass spectrometric studies of potent inhibitors of farnesyl protein transferase--detection of pentameric noncovalent complexes

Farnesyl protein transferase (FPT) inhibition is an interesting and promising approach to noncytotoxic anticancer therapy. Research in this area has resulted in several orally active compounds that are in clinical trials. Electrospray ionization (ESI) time-of-flight mass spectrometry (TOF-MS) was used for the direct detection of a 95 182 Da pentameric noncovalent complex of alpha/beta subunits of FPT containing Zn, farnesyl pyrophosphate (FPP) and SCH 66336, a compound currently undergoing phase III clinical trials as an anticancer agent. It was noted that the desalting of protein samples was an important factor in the detection of the complex. This study demonstrated that the presence of FPP in the system was necessary for the detection of the FPT-inhibitor complex. No pentameric complex was detected in the spectrum when the experiment was carried out in the absence of the FPP. An indirect approach was also applied to confirm the noncovalent binding of SCH 66336 to FPT by the use of an off-line size exclusion chromatography followed by liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) for the detection of the inhibitor.     

Microwave enhanced Akabori reaction for peptide analysis

The Akabori reaction, devised in 1952 for the identification of C-terminus amino acids, involves the heating of a linear peptide in the presence of anhydrous hydrazine in a sealed tube for several hours. We report here a modified Akabori reaction that rapidly identifies the C-terminus amino acid in a polypeptide including its amino acid sequence information at both the C-terminus and the N-terminus. This modified methodology demonstrates the fundamentals of microwave chemistry applied to bioanalytical problems. In this modified process, hydrazinolysis has been accelerated by the application of microwave irradiation. In our reaction, the linear peptide and hydrazine solution, contained in a loosely covered conical flask, was exposed to a few minutes of irradiation using an unmodified domestic microwave oven. While the classical Akabori reaction required several hours, the microwave assisted reaction takes just minutes. If dimethyl sulfoxide is added to dilute the reaction mixture, the process is retarded enough to allow aliquots of the reaction mixture to be drawn every few minutes over a period of about an hour in order to study the progress of hydrazinolysis. Reaction products were monitored by mass spectrometry-primarily FAB-MS. In addition to providing sequence information, the microwave enhanced Akabori reaction quickly detects the presence of arginine (Arg) by converting each Arg to ornithine (Orn). Furthermore, certain amino acids, containing beta-SH, CO2H, and CONH2 groups in their side chain, are susceptible to modification by hydrazine, thereby, providing rapid confirmation of the presence of these amino acid residues. In these preliminary studies, the following oligopeptides were analyzed to demonstrate the effectiveness of our approach; the dipeptide (Trp-Phe), the tripeptide (Tyr-Gly-Gly), the tetrapeptide (Pro-Phe-Gly-Lys), the heptapeptide (Ala-Pro-Arg-Leu-Arg-Phe-Tyr), and a N-terminal blocked tripeptide (N-acetyl-Met-Leu-Phe).     

利福霉素钠注射液的制备与质量研究

采用高效液相色谱法测定利福霉素钠的含量并对相关物质进行检测.所得样品质量稳定.制剂组方含理、质量可控、性质稳定.     

内禀退相干下海森伯XY模型中的热纠缠性质及其相干调控

通过求解系统的Milburn方程,研究了内禀退相干下两比特海森伯XY模型中的热纠缠性质. 讨论了非均匀磁场、系统初始纠缠度、 两比特的相对相位对系统热纠缠的调控作用.结果表明:在系统一定的初始条件下, 磁场的引入能够大大提高两比特间的热纠缠 程度;在固有退相干存在的情况下,系统热纠缠强烈依赖于两个自旋比特的初始态, 通过控制两自旋比特的相对相位和振幅,可以 获得系统的稳定热纠缠.结果还表明:在没有外界磁场时,发现Bell正交态是系统的"暗态", 它的热纠缠度在演化过程中不受系 统内禀退相干的影响.