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751.
Polymer dispersed liquid crystals (PDLCs) have been extensively studied for various excellent electro-optical applications. The anchoring interaction of liquid crystals (LCs) molecules on the surface of the polymer cavity surrounding an LCs droplet has a crucial effect on the electro-optical performance of the PDLCs. The effect of polymerizable surfactants on the electro-optical properties of PDLCs films was studied in detail. The active double bonds were polymerized with prepolymer to stabilize the performance of polymer matrix. The experimental results showed that polymerizable surfactants could effectively reduce the driving voltage. The speed of polymerization was monitored by real-time transmittance. The electro-optical properties of PDLC films were measured by Polarimeter (PerkinElmer Model 341). The driving electric field was reduced from 3.9 V/μm to about 2.8 V/μm for doping undec-10-enoic acid at curing temperature 80?°C. The surfactants containing polymerizable functional groups, polarity, and alkyl chain weakened the surface anchoring between LCs droplets and polymer interface. The morphologies of PDLCs films were also investigated by polarizing optical microscopy (POM) and Fourier transform infrared (FTIR) images. The LC droplets were encapsulated by polymerizable surfactant according to FTIR images. 相似文献
752.
In this paper, a food chain model with Ivlev functional response and impulsive effect of top predator is investigated. Conditions for extinction of mid-level predator are given. By using the Floquet theory of linear τ-period impulsive differential equation and small amplitude perturbation skills, we show that the lowest-level prey and the mid-level predator extinction periodic solution is unstable, while the mid-level predator eradication periodic solution is stable, and meanwhile, we prove that the system is permanent if the impulsive period is larger than some critical value. Furthermore, influences of the impulsive perturbation on the inherent oscillation are studied numerically, which displays complicated behavior including a sequence of direct and inverse cascade of period doubling, period halfing as well as chaos. 相似文献
753.
In this paper, we study a new SVEIRS infectious disease model with pulse and two time delays. The pulse vaccination strategy is used as an effective strategy for the elimination of infectious disease. The model consists of a set of integro-differential equations. The existence and global attractivity of ‘infection-free’ periodic solution, permanence of an endemic model are investigated. 相似文献
754.
Xinyu Zhang Ti Chen Alan T.K. Wan Guohua Zou 《Journal of multivariate analysis》2009,100(10):2376-2388
The Stein-rule (SR) and positive-part Stein-rule (PSR) estimators are two popular shrinkage techniques used in linear regression, yet very little is known about the robustness of these estimators to the disturbances’ deviation from the white noise assumption. Recent studies have shown that the OLS estimator is quite robust, but whether this is so for the SR and PSR estimators is less clear as these estimators also depend on the F statistic which is highly susceptible to covariance misspecification. This study attempts to evaluate the effects of misspecifying the disturbances as white noise on the SR and PSR estimators by a sensitivity analysis. Sensitivity statistics of the SR and PSR estimators are derived and their properties are analyzed. We find that the sensitivity statistics of these estimators exhibit very similar properties and both estimators are extremely robust to MA(1) disturbances and reasonably robust to AR(1) disturbances except for the cases of severe autocorrelation. The results are useful in light of the rising interest of the SR and PSR techniques in the applied literature. 相似文献
755.
In this study, we present empirical analysis of statistical properties of mating networks in genetic algorithms (GAs). Under the framework of GAs, we study a class of interaction network model—information flux network (IFN), which describes the information flow among generations during evolution process. The IFNs are found to be scale-free when the selection operator uses a preferential strategy rather than a random. The topology structure of IFN is remarkably affected by operations used in genetic algorithms. The experimental results suggest that the scaling exponent of the power-law degree distribution is shown to decrease when crossover rate increases, but increase when mutation rate increases, and the reason may be that high crossover rate leads to more edges that are shared between nodes and high mutation rate leads to many individuals in a generation possessing low fitness. The magnitude of the out-degree exponent is always more than the in-degree exponent for the systems tested. These results may provide a new viewpoint with which to view GAs and guide the dissemination process of genetic information throughout a population. 相似文献
756.
The redox reaction is a normal process of biological metabolism in the body that leads to the production of free radicals. Under conditions such as pathogenic infection, stress, and drug exposure, free radicals can exceed normal levels, causing protein denaturation, DNA damage, and the oxidation of the cell membrane, which, in turn, causes inflammation. Acanthopanax senticosus (A. senticosus) flavonoids are the main bioactive ingredients with antioxidant function. H2O2-treated RAW 264.7 cells and DSS-induced colitis in mice were used to evaluate the antioxidant properties of A. senticosus flavonoids. The results show that A. senticosus flavonoids can significantly downregulate the levels of ROS and MDA in H2O2-treated RAW 264.7 cells and increase the levels of CAT, SOD, and GPx. A. senticosus flavonoids can also increase the body weights of DSS-induced colitis mice, increase the DAI index, and ameliorate the shortening of the colon. ELISA experiments confirmed that A. senticosus flavonoids could reduce the level of MDA in the mouse serum and increase the levels of SOD, CAT, and GPx. Histopathology showed that the tissue pathological changes in the A. senticosus flavonoid group were significantly lower than those in the DSS group. The Western blot experiments showed that the antioxidant capacity of A. senticosus flavonoids was accomplished through the Nrf2 pathway. In conclusion, A. senticosus flavonoids can relieve oxidative stress in vivo and in vitro and protect cells or tissues from oxidative damage. 相似文献
757.
Zhaohang Zuo Shuting Liu Weiqiao Pang Baoxin Lu Wei Sun Naidan Zhang Xinyu Zhou Dongjie Zhang Ying Wang 《Molecules (Basel, Switzerland)》2022,27(9)
Accumulating attention has been focused on resistant starch (RS) due to its blood-lipid-lowering activities. However, reports on the potential bioactivities of RS for preventing hyperlipidemia acute pancreatitis (HLAP) are limited. Therefore, in this study, an acute pancreatitis model was set up by feeding a hyperlipidemia diet to rats, and subsequently evaluating the anti-HLAP effect of RS in kidney beans. The results show that the IL-6, IL-1β, and TNF-α of serum in each RS group were decreased by 18.67–50.00%, 7.92–22.89%, and 8.06–34.04%, respectively, compared with the model group (MOD). In addition, the mRNA expression of tight junction protein ZO-1, occludin, and antibacterial peptides CRAMP and DEFB1 of rats in each RS group increased by 26.43–60.07%, 229.98–279.90%, 75.80–111.20%, and 77.86–109.07%, respectively. The height of the villi in the small intestine and the thickness of the muscle layer of rats were also increased, while the depth of the crypt decreased. The present study indicates that RS relieves intestinal inflammation, inhibits oxidative stress, and prevents related intestinal barrier damage. These results support the supplementation of RS as an effective nutritional intervention for HLAP and associated intestinal injury. 相似文献
758.
Xinyu Zhang Jianqing Su Xiaoya Wang Xueyan Wang Ruixue Liu Xiang Fu Ying Li Jiaojiao Xue Xiaoli Li Rui Zhang Xiuling Chu 《Molecules (Basel, Switzerland)》2022,27(9)
In order to improve the aqueous solubility and enhance the bioavailability of Hyperoside (Hyp), three inclusion complexes (ICs) of Hyp with 2-hydroxypropyl-β-cyclodextrin (2H-β-CD), β-cyclodextrin (β-CD), and methyl-β-cyclodextrin (M-β-CD) were prepared using the ultrasonic method. The characterization of the inclusion complexes (ICs) was achieved using Fourier-transform infrared spectroscopy (FTIR), scanning electronic microscopy (SEM), X-ray powder diffraction (XRPD), thin-layer chromatography (TLC), and 1H nuclear magnetic resonance (1H NMR). The effects of the ICs on the solubility and antioxidant activity of Hyp were investigated. A Job’s plot revealed that the Hyp formed ICs with three kinds of cyclodextrin (CD), all at a 1:1 stoichiometric ratio. The FTIR, SEM, XRPD, TLC, and 1H NMR results confirmed the formation of inclusion complexes. The water solubility of the IC of Hyp with 2-hydroxypropyl-β-cyclodextrin was enhanced 9-fold compared to the solubility of the original Hyp. The antioxidant activity tests showed that the inclusion complexes had higher antioxidant activities compared to free Hyp in vitro and the H2O2–RAW264.7 cell model. Therefore, encapsulation with CDs can not only improve Hyp’s water solubility but can also enhance its biological activity, which provides useful information for the potential application of complexation with Hyp in a clinical context. 相似文献
759.
Xianbo Wu Mei Wen Yuyan Zou Xinyu Gao Chuanwan Wei Renyu Liu Jianghua Li Long Wang Xilong Li You-Nian Liu Wansong Chen 《Chemical science》2022,13(23):6842
Catalytic nanomedicine with the innate features of catalysts brings incomparable properties to biomedicine over traditional drugs. The temperature-dependent activity of catalysts provides catalytic nanomedicines with a facile strategy to control their therapeutic performance. Tuning catalytic nanomedicine by cold treatment (4–37 °C) is safe and desired for practical applications, but there is a lack of cold-catalytic platforms. Herein, with black phosphorus (BP) as a model pyroelectric nanocatalyst, we explored the potential of cold-catalysts for antitumor therapy. BP nanosheets with pyro-catalytic activity catalyze the generation of oxidative stress to activate antitumor immunity under cold treatment. Due to the cold-catalytic immunomodulation, immune memory was successfully achieved to prevent tumor metastasis and recurrence. Considering the safety and conductive depth (>10 mm) of cold in the body, pyroelectric nanocatalysts open up exciting opportunities for the development of cold-catalytic nanomedicine.Cold-catalytic nanomedicine and the concept of cold-catalytic immunotherapy are explored with black phosphorus as a model cold catalyst. 相似文献
760.
Li Liao Xinyu Guan Haorui Zheng Zerong Zhang Yaozu Liu Hui Li Liangkui Zhu Shilun Qiu Xiangdong Yao Qianrong Fang 《Chemical science》2022,13(32):9305
Covalent organic frameworks (COFs) have attracted extensive interest due to their unique structures and various applications. However, structural diversities are still limited, which greatly restricts the development of COF materials. Herein, we report two unusual cubic (8-connected) building units and their derived 3D imine-linked COFs with bcu nets, JUC-588 and JUC-589. Owing to these unique building blocks with different sizes, the obtained COFs can be tuned to be microporous or mesoporous structures with high surface areas (2728 m2 g−1 for JUC-588 and 2482 m2 g−1 for JUC-589) and promising thermal and chemical stabilities. Furthermore, the high selectivity of CO2/N2 and CO2/CH4, excellent H2 uptakes, and efficient dye adsorption are observed. This research thus provides a general strategy for constructing stable 3D COF architectures with adjustable pores via improving the valency of rigid building blocks.Two unusual cubic (8-connected) building units and their derived 3D imine-linked COFs based on bcu nets have been designed and synthesized, which demonstrates highly crystalline structures, excellent surface areas, and large pore sizes. 相似文献