全文获取类型
收费全文 | 2474篇 |
免费 | 322篇 |
国内免费 | 271篇 |
专业分类
化学 | 1699篇 |
晶体学 | 29篇 |
力学 | 165篇 |
综合类 | 22篇 |
数学 | 241篇 |
物理学 | 911篇 |
出版年
2024年 | 3篇 |
2023年 | 47篇 |
2022年 | 88篇 |
2021年 | 108篇 |
2020年 | 99篇 |
2019年 | 91篇 |
2018年 | 73篇 |
2017年 | 89篇 |
2016年 | 132篇 |
2015年 | 120篇 |
2014年 | 164篇 |
2013年 | 164篇 |
2012年 | 243篇 |
2011年 | 289篇 |
2010年 | 140篇 |
2009年 | 179篇 |
2008年 | 131篇 |
2007年 | 127篇 |
2006年 | 136篇 |
2005年 | 84篇 |
2004年 | 86篇 |
2003年 | 55篇 |
2002年 | 51篇 |
2001年 | 30篇 |
2000年 | 47篇 |
1999年 | 43篇 |
1998年 | 35篇 |
1997年 | 33篇 |
1996年 | 33篇 |
1995年 | 21篇 |
1994年 | 26篇 |
1993年 | 24篇 |
1992年 | 20篇 |
1991年 | 12篇 |
1990年 | 8篇 |
1989年 | 4篇 |
1988年 | 5篇 |
1987年 | 12篇 |
1986年 | 8篇 |
1985年 | 1篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1959年 | 1篇 |
1957年 | 2篇 |
排序方式: 共有3067条查询结果,搜索用时 15 毫秒
81.
82.
Viscous Shock Wave to an Inflow Problem for Compressible Viscous Gas with Large Density Oscillations
Acta Mathematicae Applicatae Sinica, English Series - This paper is concerned with the inflow problem for one-dimensional compressible Navier-Stokes equations. For such a problem, Huang, Matsumura,... 相似文献
83.
Wu Yitian Zhang Xiaojun Zhou Haoxi Zhang Jinming 《Journal of Radioanalytical and Nuclear Chemistry》2022,331(6):2705-2717
Journal of Radioanalytical and Nuclear Chemistry - Prostate-specific membrane antigen (PSMA)-targeted radiolabeled agents have been developed to diagnose and treat prostate cancer. In this study,... 相似文献
84.
Yuxin An Qian Li Jiejun Chen Xiaokang Gao Hongwei Chen Chaoni Xiao Liujiao Bian Jianbin Zheng Xinfeng Zhao Xiaohui Zheng 《Biomedical chromatography : BMC》2014,28(12):1881-1886
A new mathematical model and frontal analysis were used to characterize the binding behavior of caffeic acid to human serum albumin (HSA) based on high‐performance affinity chromatography. The experiments were carried out by injecting various mole amounts of the drug onto an immobilized HSA column. They indicated that caffeic acid has only one type of binding site to HSA on which the association constant was 2.75 × 104/m . The number of the binding site involving the interaction between caffeic acid and HSA was 69 nm . The data obtained by the frontal analysis appeared to present the same results for both the association constant and the number of binding sites. This new model based on the relationship between the mole amounts of injection and capacity factors assists understanding of drug–protein interaction. The proposed model also has the advantages of ligand saving and rapid operation. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
85.
Yujie Hua Xican Li Wenhui Zhang Ban Chen Yamei Liu Xiaojun Zhao Hong Xie Dongfeng Chen 《Journal of Saudi Chemical Society》2021,25(7):101272
Folium Hibisci Mutabilis, a new member of Chinese Pharmacopoeia, can treat some diseases induced by reactive oxygen species. The study prepared a lyophilized aqueous extract of Folium Hibisci Mutabilis (LAFHM). LAFHM was found to enrich eight flavonoids (i.e., quercetin, luteolin, hyperoside, isoquercitrin, rutin, kaempferol, tiliroside, and vitexin) by HPLC analysis. These flavonoids were further compared using antioxidant assays, where triliroside and vitexin always exhibited higher IC50 values than the others. In ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry analysis, these flavonoids could basically give two characteristic m/z values (226 and 196) and their corresponding double m/z values (i.e., 602, 570, 926, 926, 570, 1186, and 862), when treated by 1,1-diphenyl-2-picryl-hydrazl radical (DPPH?). Finally, the coupling products of DPPH?-treated triliroside were investigated using computational chemistry. It was found that the –OH in para-coumaroyl moiety to have the lowest bond disassociation energy among all phenolic -OHs in the triliroside. In conclusion, Folium Hibisci Mutabilis contains the above eight antioxidant flavonoids. Despite of the different antioxidant levels, they can generally produce flavonoid-radical coupling product and flavonoid-flavonoid homodimer during antioxidant process. Especially, tiliroside uses para-coumaroyl as linker to construct a tiliroside-radical coupling product at the meta-carbon atom. 相似文献
86.
Dr. Jinghui Zhang Lei Gong Xiaoshuang Zhang Dr. Mengliang Zhu Chaorui Su Qing Ma Dr. Dongdong Qi Prof. Yongzhong Bian Prof. Hongwu Du Prof. Jianzhuang Jiang 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(61):13842-13848
Two-photon excited fluorescent (TPEF) materials are highly desirable for bioimaging applications owing to their unique characteristics of deep-tissue penetration and high spatiotemporal resolution. Herein, by connecting one, two, or three electron-deficient zinc porphyrin units to an electron-rich triazatruxene core via ethynyl π-bridges, conjugated multipolar molecules TAT-(ZnP) n (n=1–3) were developed as TPEF materials for cell imaging. The three new dyes present high fluorescence quantum yields (0.40–0.47) and rationally improved two-photon absorption (TPA) properties. In particular, the peak TPA cross section of TAT-ZnP (436 GM) is significantly larger than that of the ZnP reference (59 GM). The δTPA values of TAT-(ZnP)2 and TAT-(ZnP)3 further increase to 1031 and up to 1496 GM, respectively, indicating the effect of incorporated ZnP units on the TPA properties. The substantial improvement of the TPEF properties is attributed to the formation of π-conjugated quadrapole/octupole molecules and the extension of D -π-A-D systems, which has been rationalized by density function theory (DFT) calculations. Moreover, all of the three new dyes display good biocompatibility and preferential targeting ability toward cytomembrane, thus can be superior candidates for TPEF imaging of living cells. Overall, this work demonstrated a promising strategy for the development of porphyrin-based TPEF materials by the construction and extension of D -π-A-D multipolar array. 相似文献
87.
Zhimei Wei Quanchao Zhang Lihua Wang Minle Peng Xiaojun Wang Shengru long Jie Yang 《Journal of Polymer Science.Polymer Physics》2012,50(20):1414-1420
The focus of this work is the preparation of aramid nanofibers via electrospinning technology and the study of their adsorption properties. In this article, aramid nanofibers were prepared by electrospinning aramid fibers solution with the addition of lithium chloride (LiCl). It showed a good adsorption capacity when methylene blue (MB) was used as the model target. There were much larger adsorption amounts and faster kinetics of uptaking target species of electrospun aramid nanofibers to MB than that of electrospun polyethersulfone (PES) nanofibers. Compared with activated carbon, aramid nanofibers also have a much faster adsorption rate to MB. Aramid nanofibers were subsequently used to effectively remove endocrine disruptors such as bisphenol A (BPA), phenol (Phe), and p‐hydroquinone (BPhe) from their aqueous solutions. Additionally, molecule imprinted technology enhances aramid nanofibers with much higher adsorption amounts and special adsorption property for endocrine disruptors. These results showed that aramid nanofibers have the potential to be used in environmental applications. © 2012 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2012 相似文献
88.
Chunying Li Xiaoguo Ma Xiaojun Zhang Rui Wang Yuan Chen Zhongyang Li 《Analytical and bioanalytical chemistry》2016,408(27):7857-7864
89.
90.
Herein we discovered that a Nile Red-based probe with a cinnamoyl unit was highly selective and sensitive to N2H4. Hydrazinolysis by N2H4 would release a hydroxyl substituted Nile Red and result in remarkable fluorescence quench. Importantly, Cys/Hcy would not interrupt the N2H4 recognition. This is because, for this probe, the combination of the π-π conjugate system can stabilize the ethylene union, which results in the nucleophilic addition of the thiol group of Cys/Hcy becomes non-effective. 相似文献