LyP-1 peptide-functionalized gold nanoprisms for SERRS imaging and tumor growth suppressing by PTT induced-hyperthermia

The gold nanoprisms (GNPs) have exhibited special plasmonic properties for biomedical applications because of their unique shapes and dimensions. Based on their optical performance, the NIR dye IR780 not only enabled the GNPs-based nanosystem as SERRS nanoparticles for Raman-encoded molecular imaging, but also enhanced the plasmonic photothermal property by laser irradiation. Meanwhile, the GNPs/IR780-Lyp-1 by introduction of tumor-homing peptide segment LyP-1, which presents high affinity to p32 protein, demonstrated the increased enrichment in tumor region and enhanced photothermal therapy efficacy.     

循环伏安法对自组装分子沉积膜屏蔽效应的研究

用循环伏安法研究了分子沉积（ＭＤ）膜的屏蔽效应，讨论了不同条件对其成膜性和稳定性的影响，得到了金电极表面沉积规整ＭＤ膜的一般机制和佳成膜条件，证实了ＭＤ膜的自发有序排列的组装过程。     

电化学方法对两性接枝星形聚合物LB膜屏蔽效应的研究

本文将自制Y式玻碳电极拉上两性接枝星形聚合物(GPSMA)的LB膜,用循环伏安法研究谈膜的屏蔽效应,讨论了接枝量、成膜条件等对膜缺陷的影响,并提出了减少缺陷的办法。     

Synthesis, crystal structure and studies on properties of trisodium 5,3′,5′-trisulfonate-2,3,4,4′-tetrahydroxy-deoxybenzoin

A new water soluble compound trisodium 5,3′,5′-trisulfonate-2,3,4,4′-tetrahydroxy-deoxybenzoin (TTDB) was synthesized and characterized by IR, UV, ¹H NMR, and elemental analysis. The single crystal of TTDB was determined by X-ray single crystal diffraction. The scavenging effect of compounds on hydroxy radicals was detected by fluorescent spectrophotometry. The electrochemical behavior of compounds in nonaqueous solution DMF was carried out by means of cyclic voltammetry. The experimental result shows that the crystal [C₁₄H₁₇Na₃O₁₈S₃] belongs to monoclinic, space group C2/c with unit cell constants a = 1.4223(4) nm, b = 2.4327(8) nm, c = 1.3596(4) nm, α = 90°, β = 113.044(5)°, γ = 90°, Z = 8, V = 4.329(2) nm³, D _c = 1.925 mg/m³, F(000) = 2568, F _w = 638.43, R ₁ = 0.0950, wR ₂ = 0.2648. The half effective concentration EC₅₀ of scavenging hydroxy radicals of compound THDB is 53.1 μmol/L, while that of scavenging hydroxy radicals of compound TTDB is 47.3μmol/L. The electrochemistry redox processes of THDB and TTDB are different from each other. __________ Translated from Chemical Journal of Chinese Universities, 2005, 26(9) (in Chinese)     

高效液相色谱-质谱法测定水产品中孔雀石绿及其代谢物

在水产养殖过程中,人们经常使用各种药物进行水体消毒和防止鱼病害,孔雀石绿就是其中的一种染料类杀菌剂,近年来发现它特别是其代谢物在水产体内有明显的残留现象,且代谢物的残留时间较长,由于孔雀石绿化学官能团三苯甲烷是一种致癌物质,所以欧盟、美国等宣布禁止其在经济鱼类(观赏鱼除外)养殖过程中使用。经文献检索,国内虽有水产品中孔雀石绿残留量检验方法的报道,但未涉及代谢物残留量检测方法的报道。国外已建立的检测方法主要采用了气相色谱质谱联用法测定孔雀石绿代谢物、高效液相-色谱法同时测定孔雀石绿及其代谢物和高效液相色谱-质谱法同时测定孔雀石绿及其代谢物。我们利用HPLC-VIS和Q-TOFMS技术分别建立了高效液相色谱法(初筛法)和高效液相串联质谱法(确证法)两种检测方法。     

Norditerpenoid Alkaloids from the Roots of Aconitum hemsleyanum Pritz.var.Pengzhouense

In continuation of our studies on Aconitum hemsleyanum Pritz.var. pengzhouense, two new norditerpenoid alkaloids, pengshenines A(1) and B(2),have isolated from the roots of the plants and their strucures were elucidated by 1D-and 2D-NMR.     

甲基丙烯酸—磷脂酰乙醇甲基丙烯酰胺共聚物LB膜的研究

制备了不同摩尔比的甲基丙烯酸-磷脂酰乙醇甲基丙烯酰胺共聚物,研究了这种共聚物在水面的表面压力(π)-分子面积(A)曲线、共聚物制成的MOS LB膜的电容(C)-电压(V)特性及此LB膜的相变温度。     

Synthesis and Structure of a 1,3-alternate-Thiacalix[4]arene diamide Derivative

A novel receptor possessing two complexation sites and bearing 1,3-alternate conformation based on thiacalix[4]arene, confirmed by single crystal X-ray analysis, was prepared. The tetrathiacalix[4]arene diamide shows strong intramolecular hydrogen bonding. The binding behavior towards K⁺ and halides has been examined by ¹H NMR titration experiments.     

功能性超薄有序分子沉积膜的制备及其结构研究

1991年G.Decher等首次探讨了阴阳离子与聚电解质交替沉积制备有机超薄膜的方法。我们在完善成膜技术和发展成膜基质的基础上,详细研究了其成膜过程与膜的结构,并定义这种新的自组装超薄有序膜为分子沉积膜——MD膜。MD膜是利用阴阳离子的静电吸附反应特性,通过相反离子体系的交替分子沉积制备的层状有序自组装多层超薄膜。需要指出的是,分子沉积既是有机超薄膜的制备技术,本身又是一种自组装超薄有序膜。MD膜制备工艺简单,热稳定性和长期稳定性好,不受基体形状与面积限制。     

A note of a modular equation of Ramanujan–Selberg continued fraction

The Ramanujan Journal - We show that if $$E/\mathbb {Q}$$ is an elliptic curve with a rational p-torsion for $$p=2$$ or 3, then there is a congruence relation between Ramanujan’s tau function...