全文获取类型
收费全文 | 2090篇 |
免费 | 124篇 |
国内免费 | 13篇 |
专业分类
化学 | 1557篇 |
晶体学 | 10篇 |
力学 | 65篇 |
数学 | 321篇 |
物理学 | 274篇 |
出版年
2024年 | 5篇 |
2023年 | 15篇 |
2022年 | 24篇 |
2021年 | 41篇 |
2020年 | 31篇 |
2019年 | 41篇 |
2018年 | 32篇 |
2017年 | 41篇 |
2016年 | 88篇 |
2015年 | 54篇 |
2014年 | 110篇 |
2013年 | 130篇 |
2012年 | 162篇 |
2011年 | 185篇 |
2010年 | 109篇 |
2009年 | 111篇 |
2008年 | 144篇 |
2007年 | 133篇 |
2006年 | 121篇 |
2005年 | 113篇 |
2004年 | 114篇 |
2003年 | 81篇 |
2002年 | 72篇 |
2001年 | 35篇 |
2000年 | 32篇 |
1999年 | 22篇 |
1998年 | 22篇 |
1997年 | 19篇 |
1996年 | 17篇 |
1995年 | 11篇 |
1994年 | 12篇 |
1993年 | 6篇 |
1992年 | 6篇 |
1991年 | 8篇 |
1989年 | 3篇 |
1988年 | 4篇 |
1987年 | 6篇 |
1986年 | 4篇 |
1985年 | 17篇 |
1984年 | 7篇 |
1983年 | 3篇 |
1982年 | 4篇 |
1981年 | 4篇 |
1980年 | 3篇 |
1979年 | 6篇 |
1977年 | 4篇 |
1976年 | 2篇 |
1975年 | 2篇 |
1971年 | 2篇 |
1958年 | 2篇 |
排序方式: 共有2227条查询结果,搜索用时 15 毫秒
71.
Dr. Tarun Kumar Yan Yang Sirine Sghaier Dr. Yassir Zaid Dr. Xavier F. Le Goff Dr. Elodie Rousset Dr. Fabien Massicot Dr. Dominique Harakat Agathe Martinez Dr. Marc Taillefer Prof. Laurent Maron Prof. Jean-Bernard Behr Dr. Florian Jaroschik 《Chemistry (Weinheim an der Bergstrasse, Germany)》2021,27(12):4016-4021
The development of new fluorine-containing building blocks and their efficient synthetic access is currently a challenging research field. Herein, the highly regio- and stereoselective addition of a large range of aldehydes onto trifluoromethylated benzofulvenes was achieved using a simple La/I2/DIBAL-Cl system via a selective C−F bond activation process. This versatile methodology provided homodienyl alcohols bearing a terminal CF2-alkene with potential further applications, as shown by the dehydration to the first benzofulvenes carrying a difluorovinyl group. In addition, for certain electron-poor aldehydes, unprecedented ipso substitution of the CF3 group in a diene was observed, which, according to DFT studies, is related to the presence of the large, Lewis-acidic lanthanum metal. 相似文献
72.
73.
Identifying a model by the penalized contrast procedure, we give an analytical estimation of misfitting subsets in the specific case of a least squares contrast. Then, specifying the statistical model, this allows to determine penalization rates ensuring a consistent identification. Applications are given to time series and geostatistical identification. 相似文献
74.
Dr. Antoine Nitelet Dr. Damien Thevenet Dr. Bruno Schiavi Dr. Christophe Hardouin Dr. Jean Fournier Dr. Rodolphe Tamion Prof. Dr. Xavier Pannecoucke Prof. Dr. Philippe Jubault Prof. Dr. Thomas Poisson 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(13):3262-3266
The copper-photocatalyzed borylation of aryl, heteroaryl, vinyl and alkyl halides (I and Br) was reported. The reaction proceeded using a new heteroleptic Cu complex under irradiation with blue LEDs, giving the corresponding boronic-acid esters in good to excellent yields. The reaction was extended to continuous-flow conditions to allow an easy scale-up. The mechanism of the reaction was studied and a mechanism based on a reductive quenching (CuI/CuI*/Cu0) was suggested. 相似文献
75.
Dr. Samuel Oger Damien Schapman Dr. Romain Mougeot Dr. Stéphane Leleu Dr. Noëlle Lascoux Dr. Patrice Baldeck Dr. Magalie Bénard Dr. Thibault Gallavardin Dr. Ludovic Galas Dr. Xavier Franck 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(46):10954-10964
Epicocconone 1 is a natural chromophore isolated from the fungus Epicoccum nigrum that has shown applications in proteomics and fluorescent microscopy thanks to its unique pro-fluorescence properties. The modification of the skeleton of the natural product by replacing the triene side chain by a fluorenyl scaffold can noticeably increase the fluorophore's absorption coefficient. The synthesis of the analogues of the natural product has been made possible by the use of a palladium-catalyzed carbonylation reaction, allowing the construction of the β-keto-dioxinone key intermediate. Two-photon absorption cross-section measurements of the fluorenyl epicocconone analogues show a structure dependency with values ranging from 60 to 280 GM and live cell imaging show intense staining of intracellular vesicle-like structures around the nucleus. 相似文献
76.
77.
Florent Jasinski Emeline Lobry Lénaïg Lefevre Abraham Chemtob Céline Croutxe‐Barghorn Xavier Allonas Adrien Criqui 《Journal of polymer science. Part A, Polymer chemistry》2014,52(13):1843-1853
The use of UV light to initiate emulsion polymerization processes is generally overlooked, whilst extensive literature exists on photocuring of monomer films. In this study, the unique potential of UV light to produce at ambient temperature polyacrylate latexes without initiator was exploited. Although radical initiators are utilized at low concentration, their cost, toxicity, and odor provide incentives for finding alternatives. Starting with concentrated (30 wt %) and low scattering acrylate miniemulsions (droplet diameter <100 nm), it was demonstrated that acrylate self‐initiation can promote an efficient and fast photopolymerization in micrometer‐scale reactor (spectrophotometric cell) and lab‐scale photoreactor. Herein, all kinetic, colloidal, and mechanistic aspects involved in the self‐initiation of acrylate miniemulsion were extensively examined to provide a complete picture. In particular, the effects of droplet size, initiating wavelength, optical path, and irradiance on the course of the polymerization were thoroughly discussed. A diradical self‐initiation pathway is the most likely mechanism. © 2014 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2014 , 52, 1843–1853 相似文献
78.
Jadriane A. Xavier Thaissa L. Silva Eduardo Caio Torres-Santos Camila Calado de Vasconcelos Anastacio Boane Ricardo Alexandre dos Santos Andre Felippe A. Xavier Marília O.F. Goulart 《Current Opinion in Electrochemistry》2021
This review discusses the state of the art, challenges, and perspectives in recent applications of nitroaromatics and nitroheteroaromatics, which are redox-bio-activated drugs or leads, in Medicinal Chemistry. It deals mainly with the electrochemical approach toward the electron transfer-based molecular mechanisms of drug action, drug design, estimation and measurement of redox potentials, correlation of physicochemical and pharmacological data, and electrochemical studies of the main representatives of nitro-containing prodrugs, along with approaches to combat their toxicity issues, aiming at a better therapeutic profile. Electrochemical investigation plays essential roles, being strategic in the design and discovery of potential medicines. 相似文献
79.
80.
Felipe Wodtke Fernando R. Xavier Samuel R. Mendes Alfredo R.M. de Oliveira Rogério A. Gariani 《Tetrahedron letters》2017,58(3):231-234
A novel application of the highly stable niobium oxide phosphate (NbOPO4) as an efficient catalyst for the synthesis of β-enamino ketones under solvent-free conditions is described. This protocol, exhibits attractive yields, short reaction periods, lower loading of catalyst and high chemoselectivity. 相似文献