Inflatene,an ichthyotoxic c12 hydrocarbon from the stoloniferan soft coral clavularia inflata var. luzoniana

A new tricyclic C₁₂ hydrocarbon, inflatene (1), possessing unexpected ichthyotoxic properties, has been isolated as the major metabolite of the stoloniferan $\text{Clavularia inflata}$ var. $\text{luzoniana}$. The structure of inflatene was secured by extensive FT-NMR studies with the natural product and several key derivatives.     

The kinetics of the addition of alkyl radicals to carbonyl groups. II. The addition of methyl radicals to trifluoroacetone in the gas phase. The formation reaction of the trifluoro-t-butoxy radical

By photolyzing azomethane over the temperature range 331–491 K in the presence of trifluoroacetone the kinetics of the addition reaction (1), ?H₃ + CF₃COCH₃ → CF₃C(?)(CH₃)₂ have been studied. Detailed analyses have shown that the principal product of the adduct radical, CF₃C(?)(CH₃)₂, is CH₃COCH₃ from reaction (?2), CF₃C(?)(CH₃)₂ → CH₃COCH₃ + ?F₃. The rate constant of the addition reaction has been determined to be k₁(dm³/mol s) = (4.5 ± 1.4) × 10⁷ exp(-(3370 ± 120)/T) over the temperature range 331–491 K, based on the value k₃ = 2.2 × 10¹⁰ dm³/mol s for the reaction (3), 2?H₃ → C₂H₆. The results are discussed in relation to existing data for radical additions to groups.     

Differential hydrogen exchange during the biosynthesis of fatty acids in Anacystisnidulans: the incorporation of [2,2,2-2H3, 2-13Co;1] acetate

¹³C NMR studies (with $\text{simultaneous}$¹H, ²H-decoupling) of ¹³C, ²H-labelled methyl palmitate showed a gradation of ²H-retention along the acyl chain. The results are rationalized within the known steps of fatty acid biosynthesis.