Study of the mechanism of formation of heterocyclic disulfonium dications from 1,3-benzothiazole-2-thiol and 1-iodopropan-2-one

The potential energy surface for the formation of heterocyclic disulfonium dications from 1,3-benzothiazole-2-thiol and 1-iodopropan-2-one has been analyzed at the DFT B3LYP level of theory. The reaction involves oxidation of 1,3-benzothiazole-2-thiol to the corresponding disulfide, followed by alkylation of the exocyclic sulfur atoms. Stabilization of the salt with iodide anion is initiated by thermodynamically controlled reaction with molecular iodine, leading to the formation of stable structure with triiodide anion.     

New chalcones containing carbazole and 3,4-ethylenedioxythiophene fragments

Russian Journal of Organic Chemistry - Acylation of 9-(2-ethylhexyl)carbazole with acetyl bromide in the presence of tin(IV) chloride gave 3-acetyl- and 3,6-diacetyl-9-(2-ethylhexyl)carbazoles...     

Halocyclization of 2-allyl(propargyl)sulfanyl-6-aminopyrimidin-4(3H)-ones

Russian Journal of Organic Chemistry - The alkylation of 6-amino-2-thiouracil with allyl, methallyl, and propargyl halides in the presence of bases gave 2-[allyl(methallyl,...     

Application of thermal analysis for evaluating the digestion of microwave pre-treated sewage sludge

The effect of microwave pre-treatment (MwP) on anaerobic digestion of sewage sludge was studied by means of thermal analysis and evolved gas analysis. The effect of the pre-treatment at low energy input (<1000 kJ L^?1) on sludge solubilisation was studied with the aid of response surface methodology. The pre-treatment process was subsequently studied at energies of 488–2700 kJ L^?1 to evaluate the improvement in biogas production under mesophilic conditions. Organic matter modifications were studied using a Setaram TGA92 analyser at atmospheric pressure coupled to an MSC200 quadrupole mass spectrometer from Balzers. Particle size analysis was carried out using a Laser Diffraction Particle Size Analyser LS 13 320 Beckmann Coulter for evaluating the effect of MwP on sludge particles. Results showed an increase in organic matter solubilisation with the increase in the energy applied. Modifications in the specific surface area of the organic matter due to the MwP resulted in increments in methane yields. However, an accumulation of complex compounds was observed in thermal profiles at the maximum energy input (2700 kJ L^?1). Semi-continuous digestion experiments were evaluated using as substrate pre-treated sludge at the optimum energy value (975 kJ L^?1). Results showed a significant increase in methane yield (43 %) when evaluating the process at hydraulic retention times (HRTs) of 25–10 days.     

Thin films of V2O5/MoO3 and their applications in electrochromism

Journal of Solid State Electrochemistry - Pure and doped vanadium pentoxide (V2O5, V2O5/MoO3) thin films were prepared by sol-gel method and dip coating technique. Furthermore, they were...     

An improved solvent-free synthesis of flunixin and 2-(arylamino) nicotinic acid derivatives using boric acid as catalyst

A simple solvent-free protocol for the preparation of flunixin, a potent non-narcotic, non-steroidal anti-inflammatory drugs is reported using boric acid as catalyst. Its salt, flunixin meglumine are then prepared under reflux in EtOH. This sustainable method are then extended for the synthesis of a series of 2-(arylamino) nicotinic acid derivatives. The present protocol combines non-hazardous neat conditions with associated benefits like excellent yield, straightforward workup, and use of readily available and safe catalyst in the absence of any solvent, which are important factors in the pharmaceutical industry. The pathway for catalytic activation of 2-chloronicotic acid with boric acid was also investigated using Gaussian 03 program package.

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Evaluation of the biosafety of cyanoacrylate adhesive in vitro

This paper considers the evaluation of the biosafety of cyanoacrylate adhesive in vitro on human multipotent mesenchymal stem cells. This adhesive is intended for medical use, in particular, for X-ray and endovascular interventions. A toxicity study was carried out in a culture of multipotent mesenchymal stem cells isolated from human subcutaneous fat. As a result of the work, the concentration of cyanoacrylate adhesive in lipiodol was chosen, which has the lowest toxicity.     

Adaptive symplectic conservative numerical methods for the Kepler problem

We suggest and substantiate a unified form of a family of adaptive conservative numerical methods for the Kepler problem. The family contains methods of the second, fourth, and sixth approximation order as well as an exact method. The methods preserve all the global properties of the exact solution of the problem. The variable time step is chosen automatically depending on the properties of the solution.     

O the volume growth of the hyperbolic regular $$\varvec{}$$-simplex

In this paper we give lower and upper bounds for the volume growth of a regular hyperbolic simplex, namely for the ratio of the n-dimensional volume of a regular simplex and the \((n-1)\)-dimensional volume of its facets. In addition to the methods of U. Haagerup and M. Munkholm we use a third volume form based on the hyperbolic orthogonal coordinates of a body. In the case of the ideal, regular simplex our upper bound gives the best known upper bound. On the other hand, also in the ideal case our general lower bound, improved the best known one for \(n=3\).     

Weighted inequalities for Hardy-type operators on the cone of decreasing functions in an Orlicz space

We establish criteria for the validity of modular inequalities for the Hardy operator on the cone Ω of nonnegative decreasing functions from weighted Orlicz spaces with general weight. The result is based on the theorem on the reduction of modular inequalities for positively homogeneous operators on the cone Ω, which enables passing to modular inequalities for modified operators on the cone of all nonnegative functions from an Orlicz space. It is shown that, for the Hardy operator, the modified operator is a generalized Hardy operator. This enables us to establish explicit criteria for the validity of modular inequalities.