全文获取类型
收费全文 | 1680篇 |
免费 | 193篇 |
国内免费 | 198篇 |
专业分类
化学 | 1303篇 |
晶体学 | 35篇 |
力学 | 67篇 |
综合类 | 15篇 |
数学 | 168篇 |
物理学 | 483篇 |
出版年
2024年 | 8篇 |
2023年 | 24篇 |
2022年 | 45篇 |
2021年 | 56篇 |
2020年 | 46篇 |
2019年 | 49篇 |
2018年 | 46篇 |
2017年 | 34篇 |
2016年 | 54篇 |
2015年 | 74篇 |
2014年 | 82篇 |
2013年 | 122篇 |
2012年 | 127篇 |
2011年 | 148篇 |
2010年 | 76篇 |
2009年 | 72篇 |
2008年 | 113篇 |
2007年 | 96篇 |
2006年 | 89篇 |
2005年 | 87篇 |
2004年 | 80篇 |
2003年 | 62篇 |
2002年 | 60篇 |
2001年 | 53篇 |
2000年 | 63篇 |
1999年 | 35篇 |
1998年 | 21篇 |
1997年 | 24篇 |
1996年 | 32篇 |
1995年 | 21篇 |
1994年 | 20篇 |
1993年 | 27篇 |
1992年 | 27篇 |
1991年 | 22篇 |
1990年 | 21篇 |
1989年 | 7篇 |
1988年 | 6篇 |
1987年 | 8篇 |
1986年 | 5篇 |
1985年 | 5篇 |
1984年 | 9篇 |
1983年 | 3篇 |
1981年 | 3篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 2篇 |
1973年 | 1篇 |
1970年 | 2篇 |
排序方式: 共有2071条查询结果,搜索用时 0 毫秒
71.
Lirong Ma Xuanlin Yang Xiuzhong Yao Weiyu Weng 《Photochemistry and photobiology》2020,96(5):1088-1095
Hexyl aminolevulinate (HAL) is a lipophilic derivative of 5-aminolevulinic acid (5-ALA) and can induce more protoporphyrin IX (PpIX) formation and stronger fluorescence intensity (FI) than 5-ALA, which will greatly facilitate photodynamic diagnosis and therapy. The main drawback of HAL is its low solubility in neutral aqueous media. In this study, surfactants were used to increase HAL solubility in the cell culture medium and serum, followed by in vitro fluorescence formation measurement in human pancreatic cancer cells (SW1990) and in vivo fluorescence detection in tumor-bearing mice. The results showed that Tween 80 (TW80) and Kolliphor® HS 15 (HS15) increased the solubility of HAL in the selected media. Although TW80 and HS15 exhibited in vitro cytotoxicity at high concentrations (5 mg mL−1), they facilitated fluorescent signal formation at the early stage of cell incubation. When surfactants were used, the FI should be determined without the routine washing process because surfactant-containing culture medium caused the loss of synthesized PpIX during the washing process. When HAL dissolved in TW80 solution was injected intraperitoneally into pancreatic cancer-bearing mice at a dose of 50 mg kg−1, the tumors exhibited red fluorescence, which indicated that systemic administration of surfactant-solubilized HAL might be applicable for tumor fluorescence detection in vivo. 相似文献
72.
Dr. Xingyun Li Dr. Liangping Xiao Ling Zhou Prof. Qingchi Xu Prof. Jian Weng Prof. Jun Xu Prof. Bin Liu 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(47):21292-21299
Water electrolysis offers a promising green technology to tackle the global energy and environmental crisis, but its efficiency is greatly limited by the sluggish reaction kinetics of both the cathodic hydrogen evolution reaction (HER) and anodic oxygen evolution reaction (OER). In this work, by growing amorphous multi-transition-metal (cobalt and iron) oxide on two-dimensional (2D) black phosphorus (BP), we develop a bifunctional electrocatalyst (CoFeO@BP), which is able to efficiently catalyze both HER and OER. The overpotentials for the hybrid CoFeO@BP catalyst to reach a current density of 10 mA cm−2 in 1 m KOH are 88 and 266 mV for HER and OER, respectively. Based on a series of ex-situ and in situ investigations, the excellent catalytic performance of CoFeO@BP is found to result from the adaptive surface structure under reduction and oxidation potentials. CoFeO@BP can be transformed to CoFe phosphide under reduction potential, in situ generating the real active catalyst for HER. 相似文献
73.
Bioanalysis assays that reliably quantify biotherapeutics and biomarkers in biological samples play pivotal roles in drug discovery and development. Liquid chromatography coupled with mass spectrometry (LC–MS), owing to its superior specificity, faster method development and multiplex capability, has evolved as one of the most important platforms for bioanalysis of biotherapeutics, particularly new scaffolds such as half-life extension platforms for proteins and peptides, as well as antibody drug conjugates. Intact LC–MS analysis is orthogonal to bottom-up surrogate peptide approach by providing whole molecule quantitation and high-level sequence and structure information. Here we review the latest development in LC–MS bioanalysis of intact proteins and peptides by summarizing recent publications and discussing the important topics such as the comparison between top-down intact analysis and bottom-up surrogate peptide approach, as well as simultaneous quantitation and catabolite identification. Key bioanalytical issues around intact protein bioanalysis such as sensitivity, data processing strategies, specificity, sample preparation and LC condition are elaborated. For peptides, topics including quantitation of intact peptide vs. digested surrogate peptide, metabolites, sensitivity, LC condition, assay performance, internal standard and sample preparation are discussed. 相似文献
74.
75.
GM(1,1)的周期修正模型及其在泉水流量预测中的应用 总被引:4,自引:2,他引:4
本文阐述了 GM( 1 ,1 )的残差周期修正模型 ,并将它应用于山西神头泉的流量预测中 ,建立了神头泉流量的 GM( 1 ,1 )周期修正模型 ,对其流量进行了预测 ,为神头泉域岩溶水资源开发利用和保护提供了科学依据 相似文献
76.
费米子符号在费米液体理论中至关重要. 然而, 在Mott绝缘体中, 很强的电子Coulomb相互作用抑制了体系的电荷涨落并消除了电子交换带来的费米子符号问题. 本文首先回顾二分晶格上Hubbard模型的相位弦理论, 从弱关联的费米液体到强关联的反铁磁Mott绝缘体的转变可以由此得到统一理解. 在任意Coulomb作用强度U下, 我们首先导出Hubbard模型的严格的符号结构. 在小U极限下, 它回到通常的费米子符号; 在大U极限下, 它给出了t-J模型的相位弦符号. 在半满情形下, 我们构造了一种电子分数化的表象, 其中, 电荷子与自旋子通过演生的交互Chern-Simons规范场相互耦合. 由此导出的基态波函数拟设与低能有效理论可以定性刻画Hubbard模型的基态相图. 在弱关联区域, 费米液体的准粒子由电荷子与自旋子的束缚态构成, 其长程相位相干性取决于背景自旋的关联性质. 体系的Mott转变可以通过电荷子打开能隙或是通过自旋子玻色凝聚来实现. 相似文献
77.
78.
For pairing based cryptography we need elliptic curves defined over finite fields
whose group order is divisible by some prime
with
where k is relatively small. In Barreto et al. and Dupont et al. [Proceedings of the Third Workshop on Security in Communication Networks (SCN 2002), LNCS, 2576, 2003; Building curves with arbitrary small Mov degree over finite fields, Preprint, 2002], algorithms for the construction of ordinary elliptic curves over prime fields
with arbitrary embedding degree k are given. Unfortunately, p is of size
.We give a method to generate ordinary elliptic curves over prime fields with p significantly less than
which also works for arbitrary k. For a fixed embedding degree k, the new algorithm yields curves with
where
or
depending on k. For special values of k even better results are obtained.We present several examples. In particular, we found some curves where
is a prime of small Hamming weight resp. with a small addition chain.AMS classification: 14H52, 14G50 相似文献
79.
Shangkun Weng 《Mathematical Methods in the Applied Sciences》2016,39(15):4398-4418
In this paper, we first address the space‐time decay properties for higher‐order derivatives of strong solutions to the Boussinesq system in the usual Sobolev space. The decay rates obtained here are optimal. The proof is based on a parabolic interpolation inequality, bootstrap argument, and some weighted estimates. Secondly, we present a new solution integration formula for the Boussinesq system, which will be employed to establish the existence of strong solutions for small initial data in some scaling invariant function spaces. The smallness conditions are somehow weaker than those presented by Brandolese and Schonbek. We further investigate the asymptotic profiles and decay properties of these strong solutions. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
80.
The crystal structure of α-methanol at 15K has been determined from neutron powder diffraction measurements. The structure is orthorhombic, space group P212121. The molecular geometry is found to be very similar to that in the gas phase, but the methyl group no longer has ideal 3-fold symmetry. The crystal is formed by infinite hydrogen-bonded chains of molecules with adjacent chains ‘pointing’ in opposite directions. The O-H … O hydrogen bonds are almost linear. No phase intermediate between the low temperature α-phase and the high temperature β-phase was found, but a new, metastable phase was discovered. 相似文献