Chalcones and their analogs have been an area of great interest in recent years. Numerous research papers have been published, and chalcones continue to show promise for new drug investigations. Researchers have explored new approaches for the synthesis of chalcone derivatives, which have revealed an array of pharmacological and biological effects. These chalcone derivatives have shown important antimicrobial, antifungal, anti-mycobacterial, antimalarial, antiviral, anti-inflammatory, antioxidant, antileishmanial anti-tumor, and anticancer properties. This review highlights the synthesis and pharmacological properties of chalcone derivatives. 相似文献
The free loop spaceLM of the space of smooth maps fromS1 to a finite dimensional manifoldM is a Fréchet manifold equipped with the naturalS1-action induced by the rotation. The regular cohomology theory and de Rham theorem does not deal with these symmetries. In order to involve this naturalS1-action, the equivariant cohomology theories are developed for FréchetS1-manifolds. We prove the equivariant de Rham theorem for certain class of FréchetS1-manifolds, in particular for free loop spaces. 相似文献
The electroluminescence intensity of the phenanthrene‐functionalized gold nanoparticles, PMPT‐Au nanoparticles/CPB: Ir(PIA)2 (acac) film, was increased by 4.9 times compared with control device, CPB: Ir(PIA)2 (acac) due to coupling between the excitons of emissive layer and localized surface plasmonic resonance of PMPT‐Au NPs. The maximum luminous efficiencies of devices II to IV with PMPT‐Au NPs were 39.2 cd A?1 (11.8 V), 40.1 cd A?1 (10.5 V), and 43.1 cd A?1 (9.0 V), respectively. The increment of current efficiency with PMPT‐Au NP coated devices was strongly related to the energy transfer between the radiated light generated from CBP: Ir(PIA)2 (acac) emissive layer and localized surface plasmonic resonance excited by PMPT‐Au NP layer. 相似文献
The reaction of hydroxylamine hydrochloride with ethyl 3‐aroyl‐1‐cyano‐4‐hydroxy‐2,4,6‐triarylcyclohexanecarboxylate has led to the formation of ethyl 2‐[amino(hydroxyimino)methyl]‐3‐aryl‐5‐(hydroxyimino)‐5‐arylpentanoate via a tandem ring opening and oximation process. The structures of the products are confirmed by NMR and X‐ray techniques, and the conformational features of the product arrived at are compared with a molecular dynamics simulation study. 相似文献
The synthesis of diverse N-fused heterocycles, including the pyrido[1,2-a]indole scaffold, using an efficient pyrone remodeling strategy is described. The pyrido[1,2-a]indole core was demonstrated to be a versatile scaffold that can be site-selectively functionalized. The utility of this novel annulation strategy was showcased in a concise formal synthesis of three fascaplysin congeners.The synthesis of diverse N-fused heterocycles, including the pyrido[1,2-a]indole scaffold, using an efficient pyrone remodeling strategy is described.相似文献
Journal of Thermal Analysis and Calorimetry - The thermo-physical properties of NaNO3/KNO3 (solar salt) added with Al2O3 and TiO2 nanoparticles as phase change material in thermal energy storage... 相似文献
Research on Chemical Intermediates - We present a novel and in-situ strategy to synthesize silver nanoparticles (AgNPs) onto cotton, leather, and silk fabrics by three different methods: a green... 相似文献
Mononuclear zirconium complex 3a of the molecular identity [Zr[η2-(C4H3O)C (Et) = NNPh]Cl3(THF)2], dinuclear zirconium complexes 3b [{Zr[η2-(C4H3O)C(i-Pr) = NNPh]2}2(μ2-Cl)3(μ3-Cl)2Li(Et2O)] and 3c [{Zr[η2-(C4H3O)C(t-Bu) = NNPh]2}2Cl2(μ2-Cl)2] have been synthesized by the treatment of lithium salt of (C4H3O)C(R) = NNHPh (R = CH3CH2, 1a ; R = (CH3)2CH, 1b ; R = (CH3)3C, 1c ), with different molar ratios of anhydrous zirconium tetrachloride. Of these, complex 3b was formed with lithium adduct and no such adduct was found in complex 3c . Compound 1a and all the zirconium complexes ( 3a - 3c ) were structurally characterized by single-crystal X-ray diffraction studies. Thus, it revealed that each hydrazonato ligand acts in a strained η2-coordination fashion for the three zirconium complexes. The molecular structures of the three zirconium complexes ( 3a - 3c ) reveal the existence of intramolecular hydrogen bonding interactions. Interestingly, complexes 3a and 3b assemble into a two-dimensional network structure through intermolecular hydrogen-bonding interactions. Upon activation with methylaluminoxane (MAO), all the complexes namely 3a , 3b , and 3c exhibited moderate catalytic activities toward ethylene polymerization and produced high molecular weight polyethylene with narrow molecular weight distributions. 相似文献
Paraquat dichloride commonly used as herbicide was determined by differential pulse cathodic stripping voltammetry technique. Experimental parameters, such as pH, accumulation time, accumulation potential and initial potential were optimized. In this analysis, paraquat dichloride exhibited a well-defined tworeduction peaks at ?0.35 and ?0.90 V in the pH range from 2.0 to 12.0. The 0.04 mol L–1 BR buffer at pH 2.0 was found a suitable medium for electroanalytical determination of the paraquat dichloride. Interfering ions effect was not significant. Linear calibration plots for standard solutions of paraquat dichloride were obtained in the range of 0.25 to 1.75 × 10–6 mol L–1. Detection limit was 3.66 × 10–8 mol L–1. The optimized parameters were effectively applied for the determination of commercial paraquat dichloride and in artificial samples. Artificial samples were prepared by spiking paraquat dichloride into tap water and drinking water dispenser samples. The recovery value was 90.5% in drinking water dispenser samples and 91.7% in tap water samples at the concentration range of 1.00 × 10–6 to 1.75 × 10–6 mol L–1.