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Recursive deconvolution of a 729-membered peptide library has identified three active sequences, in which both Ser and His are present in one of the two tripeptidic chains generated on a steroidal scaffold (see structural formula), for the cleavage of an activated p-nitrophenyl ester. This combinatorial approach aims at searching for serine-protease-like activity.  相似文献   
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Time-resolved and off-line synchrotron wide-angle and small-angle x-ray scattering (WAXS and SAXS) was used to study the structure formation in poly-p-phenylenebenzobisoxazole (PBO) fibers during various stages of spinning, coagulation, and heating processes. WAXS data could be explained in terms of liquid-crystalline structures of varying degrees of order. A structure model is proposed that is in accordance with the observed SAXS four-point pattern.  相似文献   
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Conclusions The purpose of this review is to acquaint the reader with the new field of ternary hydrides and to expose him to its relevance to modern energy technology. Studying their fundamental properties is one fascinating aspect in view of their novel and unusual nature. The methods of hyperfine interactions have an important role to play in their microscopic understanding, as we have illustrated through a few examples. The absorption mechanism of hydrogen has been shown to be closely related to the nature of surface overlayers and their catalytic activity. Similar measurements will be of importance also in many of the other catalytic reactions used in industry. The microscopic nature of hyperfine interaction tools also helps in determining the hydrogen site occupancy. In addition, such methods can in principle yield dynamic information which are useful in investigating relevant properties such as diffusion rates of hydrogen.Work supported by the U. S. Department of Energy  相似文献   
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