Binary volume phase masks in photo-thermo-refractive glass

Permanent binary phase masks with planar surfaces and high tolerance to laser radiation are recorded in the volume of photo-thermo-refractive glass using the contact copying technique and binary amplitude master masks. Conversion of a Gaussian beam to higher order modes is shown.     

Tripled coincidence theorems for contractive type mappings in partially ordered metric spaces

In this paper we introduce the concept of a tripled coincidence point for a pair of nonlinear contractive mappings F : X³ → X and g : X → X. The obtained results extend recent coincidence theorems due to ?iri? and Lakshmikantham [V. Lakshmikantham, L. ?iri?, L., Coupled fixed point theorems for nonlinear contractions in partially ordered metric spaces, Nonlinear Anal. 70 (2009) 4341-4349].     

New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds

Antimicrobial resistance (AMR) poses a serious threat to our society from both the medical and economic point of view, while the antibiotic discovery pipeline has been dwindling over the last decades. Targeting non-essential bacterial pathways, such as those leading to antibiotic persistence, a bacterial bet-hedging strategy, will lead to new molecular entities displaying low selective pressure, thereby reducing the insurgence of AMR. Here, we describe a way to target (p)ppGpp (guanosine tetra- or penta-phosphate) signaling, a non-essential pathway involved in the formation of persisters, with a structure-based approach. A superfamily of enzymes called RSH (RelA/SpoT Homolog) regulates the intracellular levels of this alarmone. We virtually screened several fragment libraries against the (p)ppGpp synthetase domain of our RSH chosen model Rel_Seq, selected three main chemotypes, and measured their interaction with Rel_Seq by thermal shift assay and STD-NMR. Most of the tested fragments are selective for the synthetase domain, allowing us to select the aminobenzoic acid scaffold as a hit for lead development.     

Permethylated dinuclear Mn(III) coordination nanostructure with stripe-ordered magnetic domains

A di-manganese(III) complex structure was built by an original approach consisting of a two-step procedure. First, the mononuclear complex of the manganese(III) with the Schiff base of the salen-type ligand (H₂L) derived from 1,3-bis(3-aminopropyl)tetramethyldisiloxane and 3,5-di-tert-butyl-2-hydroxybenzaldehyde was prepared. The main feature of note is the 12-membered chelate ring formed upon coordination of the Schiff base to central atom, which adopts a distorted N₂O₄ octahedron environment. In the second step, the acetato co-ligand in this complex is replaced by the carboxylate anion of a dicarboxilic acid, namely adipic acid. This metathesis reaction leads to the formation of dinuclear structure by connecting two manganese centers. The structure, as was determined by X-ray single crystal diffractometry, elemental and spectral analysis, is permethylated dinuclear complex with long aliphatic bridge. Thermal and magnetic properties were studied. In addition, the formation of magnetically induced stripe-ordered domains was highlighted by the magnetic force microscopy (MFM) on films born from diluted solution.     

Enhancing Electrocatalytic Activity through Liquid-Phase Exfoliation of NiFe Layered Double Hydroxide Intercalated with Metal Phthalocyanines in the Presence of Graphene

Earth-abundant transition-metal-based catalysts are attractive for alkaline water electrolysis. However, their catalytic properties are often limited by their poor electrical conductivity. Here, we present a strategy for enhancing the electrical conductivity of NiFe layered double hydroxide (LDH) in order to further improve its properties as an electrocatalyst for the oxygen evolution reaction (OER) in alkaline media. We show that NiFe LDH containing metal tetrasulfonate phthalocyanine in the interlayers between the NiFe oxide galleries can be coupled with graphene during liquid-phase exfoliation by taking advantage of their π-π stacking capabilities. A substantial enhancement in the electrocatalytic activity of NiFe LDH with respect to the OER was observed. Moreover, the activity and selectivity of the catalyst materials towards the oxygen reduction reaction were investigated, demonstrating that both the metal hydroxide layer and the interlayer species contribute to the electrocatalytic performance of the composite material.     

On optimality and duality for multiobjective programming problems involving generalized d-type-I and related n-set functions

In this paper we establish some optimality and duality results under generalized convexity assumptions for a multiobjective programming problem involving generalized d-type-I and related n-set functions.     

局部凸空间中最佳逼近研究纵览

通过对大量文献研究，回顾了最佳逼近论的研究进展．重点讨论了最有意义的可分离局部凸空间最佳逼近问题、以及最佳逼近问题与向量优化、Pareto有效性、多值函数等之间的直接联系．     

On the compatibility of the IPP/PA6/EPDM blends with and without functionalized IPP I. Thermo-oxidative behaviour

Binary isotactic polypropylene (IPP)/polyamide 6 (PA6) and ternary IPP/PA6/ethylene–propylene diene terpolymer (EPDM) blends in various ratios were obtained in a Haake Rheocord mixer. Processing behaviour was changed in the presence of IPP functionalized with bismaleimide (BMI), maleic anhydride (MA) and acrylic acid (AA) as reactive compatibilizing agents. The thermal and thermo-oxidative behaviour of blends was studied by differential scanning calorimetry and thermogravimetry. The functionalized IPPs modify the crystallinity degree and the decomposition behaviour of both IPP and PA6 as a result of chemical reactions of functional groups with those of the PA6. The changes depend on the IPP/PA6 or IPP/PA6/EPDM ratio, the chemical nature and amount of the functionalized IPP. On the basis of the processing and thermal data one can conclude that the compatibilizing agent effect increases in the following order: IPP-AA 相似文献   

Tailored doxycycline delivery from MCM-41-type silica carriers

Doxycycline, an antibiotic from the tetracycline class with a broad spectrum of activity, was used to prepare drug delivery systems based on pristine and functionalized mesostructured silica supports. MCM-41-type materials with different textural, structural, and surface properties were used to assess their influence on the drug release kinetics. Small- and wide-angle XRD, FTIR spectroscopy and N₂ adsorption/desorption isotherms were used to characterize the carriers before and after doxycycline loading. The drug release experiments were performed in vitro in 0.2 M phosphate buffer solution at 37 °C, and the slowest drug release kinetics was obtained for magnesium-modified MCM-41 carrier. All drug-loaded materials exhibited good antibacterial activity against Klebsiella pneumoniae ATCC 10031 strain, similar to the drug alone.