Magnetic Alignment of Rhodamine B Intercalated in Synthetic Mica

Rhodamine B was intercalated in interlayer spaces of Somasif Me-100, a synthetic mica, and the obtained rhodamine B/Somasif hybrid was suspended in a UV-curable resin precursor. Then, the suspension was subjected to an applied rotating magnetic field to align the hybrid particles, followed by solidification of the medium by UV irradiation to fix the alignment. The hybrid particles were aligned so that the Somasif layer lay perpendicular to the axis of rotation of the applied rotating magnetic field. UV/vis measurement indicated that the transition moment of xanthene ring of rhodamine B lay inclined to the layer of Somasif.     

A simple chromatographic method for determining norfloxacin and enoxacin in pharmacokinetic study assessing CYP1A2 inhibition

We developed a simple assay method for the determination of serum and urine norfloxacin and enoxacin using reversed‐phase high‐performance liquid chromatography and perchloric acid precipitation for sample pre‐treatment. Optimized conditions can permit detection of norfloxacin and enoxacin in the same chromatogram, so either compound can be used as an internal standard for another determinant. Supernatants of the precipitated samples were analyzed by the octadecylsilyl silica‐gel column under ambient temperature and an ultraviolet wavelength of 272 nm. A mobile phase solvent consisting of 20 mm sodium dihydrogenphosphate (pH 3.0) and acetonitrile (85:15, v/v) was pumped at a flow rate of 1.0 mL/min. The calibration curves for norfloxacin and enoxacin at a concentration of 62.5–1000 ng/mL for serum and 250–4000 ng/mL for urine were linear (r > 0.9997). The recoveries of norfloxacin and enoxacin from serum and urine were >94% with the coefficient of variations (CV) <5%. The CVs for intra‐ and inter‐day assay of norfloxacin and enoxacin were <4.2 and <5.5%, respectively. This method can be applied to the pharmacokinetic study of norfloxacin and enoxacin after repeated administration to assess changes in CYP1A2 activity in healthy subjects. Copyright © 2010 John Wiley & Sons, Ltd.     

On nef reductions of projective irreducible symplectic manifolds

Let X be a projective irreducible symplectic manifold and L be a non trivial nef divisor on X. Assume that the nef dimension of L is strictly less than the dimension of X. We prove that L is semiample. Partially supported by Grant-in-Aid no. 15740002 (Japan Society for Promotion of Sciences)     

Induction and inversion of chirality in poly‐L‐lysine and methyl orange complex

The mechanism of complexation of poly‐L‐lysine (PLL) with methyl orange (MO) and the appearance of induced circular dichroism (ICD) were investigated as a function of dye concentration and temperature and compared with that of the PLL‐ethyl orange complex. The formation of stoichiometric complexes with uniform size and intensities of ICDs depended on the length of alkyl groups (methyl and ethyl) as determined from quartz crystal microbalance measurement, absorption spectra, and CD spectra data. Furthermore, at constant PLL concentration, a dependence of the inversion of the ICD on the MO concentration (CMO) was observed in the PLL‐MO complexes, which to our knowledge has not been reported for a constant dye concentration system. The positive ICD in the PLL‐MO complexes observed at CMO lower than 2.0 × 10^?5 M showed reversible changes in response to heating and cooling, whereas the negative ICD in PLL‐MO complexes observed at higher CMO inverted to positive ICD values in response to a decrease in temperature. These results demonstrate the alkyl group substituent in the dye, dye concentration, and temperature play important roles in the formation of PLL‐azo dye complex and ICD appearance. © 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2011     

Synthesis of 2-(1-Hydroxyalkyl)acrylonitriles by the Cocatalysis of a Base and an Acid

Titled compounds are synthesized in good yields from acrylonitrile and saturated aliphatic aldehydes by the cocatalysis of tributylphophine and triethylaluminium.     

Growth of Shape‐ and Size‐Selective Zinc Oxide Nanorods by a Microwave‐Assisted Chemical Bath Deposition Method: Effect on Photocatalysis Properties

Herein, we demonstrate the shape‐ and size‐selective growth of ZnO nanostructures on indium tin oxide‐coated glass substrates by using a microwave‐assisted chemical bath deposition method. By systematically controlling the deposition parameters, it is possible to produce shape‐ and size‐selective nanostructures with high alignment and uniformity. Specifically, the pH of the bath can be used to control the shape of rods from bundled structures to tapered and flat tips. Furthermore, the deposition temperature can be used to control the size of the ZnO array from 770 to 125 nm. The prepared rods were active catalysts in the degradation of methylene blue under UV radiation, and exhibited size‐dependent activity.