Neosappanone A, a xanthine oxidase (XO) inhibitory dimeric methanodibenzoxocinone with a new carbon skeleton from Caesalpinia sappan

A novel dimeric methanodibenzoxocinone, named neosappanone A (1), possessing a unique unprecedented novel carbon framework, has been isolated from the heartwood of Caesalpinia sappan L. of Vietnam, and its structure was elucidated on the basis of spectroscopic analysis. Neosappanone A (1) competitively inhibited xanthine oxidase in a concentration-dependent manner (IC₅₀, 29.7 μM; K_i, 16.3 μM).     

Field Patterns of the TE Modes in Ridge-Trough Waveguide

A single-ridge waveguide with a symmetrical longitudinal trough, designated as a ridge-trough waveguide has been used as a transition in a V-band (50-75 GHz) wafer probe recently. In this paper, the field patterns for the dominant TE mode and the first higher TE mode in ridge-trough waveguide with different configurations are presented by finite element method. The field patterns in this paper have important values for us to understand the transmission characteristics of ridge-trough waveguide, and will be of practical significance in designing ridge-trough waveguide components in microwave and millimeter wave engineering.     

紫外写入光纤光栅应变传感特性研究

采用紫外写入光纤Ｂｒａｇｇ光栅研究其应变传感特性。光纤光栅要借助外界应力引起轴向应变和折射率变化造成光栅Ｂｒａｇｇ反射波长移动。在温度２０℃,利用波长在４００￣１８００ｎｍ范围色散的光谱仪并用ＩｎＧａＡｓＰ／ＩｎＰ ＥＬＤ作宽带光源,从实验上测量了光纤光栅的应变与Ｂｒａｇｇ反射波长间的关系,结果表明Ｂｒａｇｇ反波长移动与光纤光栅外界应力变化在１５５．４￣１５６．８ｎｍ波长范围呈线性。外界应力引起的     

Amyloid peptide Aβ40 inhibits aggregation of Aβ42: evidence from molecular dynamics simulations

Effects of amyloid beta (Aβ) peptide Aβ(40) on secondary structures of Aβ(42) are studied by all-atom simulations using the GROMOS96 43a1 force field with explicit water. It is shown that in the presence of Aβ(40) the beta-content of monomer Aβ(42) is reduced. Since the fibril-prone conformation N? of full-length Aβ peptides has the shape of beta strand-loop-beta strand this result suggests that Aβ(40) decreases the probability of observing N? of Aβ(42) in monomer state. Based on this and the hypothesis that the higher is the population of N? the higher fibril formation rates, one can expect that, in agreement with the recent experiment, Aβ(40) inhibit fibril formation of Aβ(42). It is shown that the presence of Aβ(40) makes the salt bridge D23-K28 and fragment 18-33 of Aβ(42) more flexible providing additional support for this experimental fact. Our estimation of the binding free energy by the molecular mechanics-Poisson-Boltzmann surface area method reveals the inhibition mechanism that Aβ(40) binds to Aβ(42) modifying its morphology.     

海口市正常儿童头发中四种微量元素含量

用电感耦合等离子体发射光谱法（ＩＣＰ－ＡＥＳ），测定了海口市２６６例正常儿童头发中锌、铁、阵、铜四种微量元素的含量，计算出海口市儿童四各微量元素的正常范围。并与其它地区文献报道值进行了比较。     

Multi-analyte HPLC–DAD Method for Concurrent Analysis of Six Antimicrobials and Three Proton Pump Inhibitors Frequently used in Management of Helicobacter pylori Infection: Application to Simulated Intestinal Fluid Samples

Chromatographia - The present work deals with the optimization, validation and application of a versatile HPLC–DAD method for concurrent estimation of nine antimicrobials and proton pump...     

Structural properties and electrochemical performance of different polymorphs of Nb2O5 in magnesium-based batteries

The selection of the most suitable crystal structure for ions storage and the investigation of the corresponding reaction mechanism is still an ongoing challeng...     

多壁碳纳米管-Nafion复合膜修饰玻碳电极测定硝苯地平的研究

研制了以Nafion分散羧基化多壁碳纳米管的化学修饰电极(Nafion-MWCNTs/GC),研究了硝苯地平(NIF)在修饰电极上的电化学行为和测定方法。实验结果表明,在0.1mol/LNH3-NH4Cl(pH9.6)溶液中,Nafion-MWCNTs/GC,对NIF具有明显的催化和增敏作用,还原峰电位由-0.85V(裸电极)正移到-0.75V(vs.AgCl/Ag)(修饰电极),灵敏度增加约7倍。对各种实验条件进行了优化。定量测定的线性范围为2.5×10-7~4.5×10-5mol/L,r为0.9974;检出限为8.0×10-8mol/L。探讨了NIF在Nafion-MWCNTs/GC上的电极过程和反应机理,测得在本体系中参与反应的质子数和电子转移数均为4,电子转移系数α为0.41。对NIF药片进行了测定,回收率为94.5%~101.0%。     

Magnetic Co3O4 nanowires,preparation and properties

The Co₃O₄ nanowires have been successfully synthesized via modified template method.The as-prepared products have been characterized by EDS,TEM and HRTEM analysis.The magnetic behavior of it is investigated by a magnetic property measurement system.The nanowires exhibit some novel magnetic properties,which are different from its bulk material.The temperature dependence curves of magnetization in zero-field-cooling and field-cooling exhibit two peaks of antiferromagnetic at blocking temperature of～23 K and～31 K,respectively.The field dependent M（H） curves of the Co₃O₄ nanowires at T = 5 and 300 K both exhibit PM properties.Moreover,the diameter of nanowires is hence determined according to the finite size effect as approximately 7-11 nm,in consistent with the characterizations by HRTEM.     

体积相位全息光栅的设计与制备

本文指出全息干版薄膜在曝光后处理过程中的收缩性和折射率变化对制备全息光栅的周期、倾斜度、布喇格入射角及衍射角的影响问题,并根据实验数据对光栅设计进行修正,再结合Kogelnik衍射方程及折射率调制度和曝光量的线性关系,在实验中基本上能准确设计出指定周期、倾斜度和衍射效率的全息光栅。