Pyrimidines. 20. Novel reactions of 5-cyano-1,3-dimethyluracil. A simple synthesis of pyrido[2,3-d]pyrimidines

A reaction of 5-cyano-1,3-dimethyluracil (1, R = CN) with acetone in base afforded 1,3,7-trimethylpyrido-[2,3-d]pyrimidine-2,4(1H,3H)dione ( 9a ) in a moderate yield. From a reaction mixture of 1 (R = CN) with butanone, 1,3,6,7-tetramethyl- and 7-ethyl-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione ( 9b and 9c , respectively) were isolated in low yields. When ethyl cyanoacetate or malononitrile was used in place of the ketone in the above reaction, 7-amino-6-ethoxycarbonyl- and 7-amino-6-cyano-1,3-dimethylpyrido[2,3-d]-pyrimidine-2,4(1H,3H)-dione ( 14a and 14b , respectively) were obtained in quantitative yields. A plausible mechanism for the formation of bicyclic compounds is discussed.     

Action Spectra for Photoinhibition of Sexual Development in Phycomyces blakesleeanus

The sexual development of the fungus Phycomyces is inhibited by light. The action spectra for this photoinhibitory effect were determined for 48 h continuous exposure between 350 and 700 nm wavelengths during the mating process. Effective wavelengths were shorter than 490 nm, but the most effective wavelengths depended on the stage of sexual development. In early stages of progametangium formation, the major peaks appeared near 360 nm with small shoulders at 410 nm, but in later stages, after gametangium formation, only single peaks were detected in the UVA range (350–390 nm). Low-fluence irradiation in the later stage, however, revealed inhibitory effectiveness at 370–410 nm, implying the existence of a dual photoresponse and multiple regulatiory systems in the mating process of Phycomyces.     

Nickel metallisation of Si by dynamic ion-beam mixing

Abstract

Thin Ni films were prepared at room temperature by Ni metal vapour deposition and simultaneous irradiation by Ar ions with an energy of 2–20 keV. The reaction of Ni with Si during dynamic ion-beam mixing was studied. The fluences of the ion beam were 4.7 × 10¹⁷ and 8.9 × 10¹⁷ cm^?2, and arrival rate ratios Ni/Ar were 9.7 and 5.1. Concentration profiles of Ni, Si, C, and O were analysed with Auger electron spectroscopy; the surface morphology and the crystalline structure were investigated with a cross-sectional scanning electron microscope and X-ray diffractometry. The theoretical profiles were calculated with the dynamic Monte Carlo simulation T-DYN for comparison with the experimentally obtained profiles. It was possible to observe the ballistic mixing effects and also thermally activated formation of nickel silicide.     

Spontaneous ignition temperature for the compacted mixture of Ni–Al system: Experiment,theory, and comparisons

Spontaneous ignition of compacted mixture has been examined not only experimentally but also theoretically, relevant to materials synthesis for Ni–Al system. Spontaneous ignition temperature, determined from the inflection-point of the temporal variation of surface temperature, is found to decrease at first, reach the minimum, and then increase gradually, with increasing size ratio, being defined as the ratio of compact and particle diameters and reported to be useful in correlating experimental results. The lowest temperature observed is as low as that, more than 200 K below the melting point 934 K of Al, at the size ratio of c.a. 700. While its decrease is attributed to the increase in the particle surface per unit spatial volume of compacted mixture, as reported in the literature, its increase found in the course of the present study can fairly be correlated to an enhancement of heat loss from each particle in the compacted mixture, by conducting a theoretical consideration. As for the dependence of spontaneous ignition temperature on the mixture ratio, a shifting occurs from a decreasing trend with increasing mixture ratio at small size ratios, less than about 700, to an insensitive trend to the mixture ratio, had not been reported in the literature. In addition, a fair degree of agreement, shown in experimental comparisons with theoretical results, indicates that the present formulation has captured the essential features of the spontaneous ignition of compacted mixture, especially for size ratios with large values. Since this kind of particle size effects, relevant to the spontaneous ignition of the compacted mixtures, has not been captured in the previous studies, its elucidation can be considered not only notable but also useful, in manipulating combustion process in materials synthesis, especially, in choosing a specific condition for the lowest spontaneous ignition temperature by varying the size ratio.     

Noncommutative differential geometry on the quantum SU(2), I: An algebraic viewpoint

We compute the cyclic homology of the coordinate ring A(SL_q(2)) of the quantum algebraic group SL _q (2). We observe a degeneration of the noncommutative de Rham complex. The results are also verified from the point of view of Connes' noncommutative differential geometry.     

The local time of self-intersections of Brownian motions as generalized Brownian functionals

In this Letter, we show that the local time of self-intersections ofd-dimensional Brownian motions is a generalized Brownian functional in the sense of Hida.     

Development of high resolution resonance ionization mass spectrometry for trace analysis of 93mNb

⁹³Nb(n, n′)^93mNb reaction allows retrospective estimation of integrated fast neutron dose in nuclear reactor. We proposed isomer-selective trace analysis of ^93mNb by Resonance Ionization Mass Spectrometry (RIMS) combined with a gas-jet atomic source and an injection locked Ti:Sapphire laser system operated at several kHz. Resonant ionization spectroscopy of Nb in gas-jet using Ti:Sapphire laser was demonstrated.     

The control of very low oxygen partial pressures with stabilized zirconia cell

Control of very low oxygen partial pressures was performed in the range of 10⁻²¹-10⁻²⁴ Pa at 750°C by pumping oxygen into the purified hydrogen stream with a stabilized zirconia cell. The oxygen partial pressures were monitored by a stabilized zirconia sensor. The stabilized zirconia oxygen sensor was calibrated by H₂-CO₂ gas buffer mixture in the range of oxygen pressure from 10⁻¹⁷ to 10⁻²¹ Pa, and oxygen partial pressures below 10⁻²¹ Pa were measured by extrapolating the calibration line to very low oxygen partial pressures. The lowest oxygen partial pressure controlled was 10⁻²⁴ Pa at 750°C, which was limited by gas leaks in the system and also by the reduction of the ionic transference number in solid electrolyte used as the oxygen pump.