Molecular modeling of the binding mode of chiral metal complexes A- and A-[Co(phen)_2dppz]~(3 ) with B-DNA

Molecular modeling methods have been applied to the structural characterization of the interaction between chiral metal complexes [Co(phen)2dppz]3 (where phen = 1, 10-phenanthroline, dppz = dipyrido[3,2-a: 2', 3'-c]phenazine) and the oligonucleotide (B-DNA fragment). The natures of two kinds of the binding modes, which are currently intense controversy, have been explored. Barton proposed that there is enantio-selective DMA binding by the octahedral complexes and intercalative access by these complexes from the major groove; but Norden suggested that both enantiomers bind extremely strongly to DNA from the minor groove without any noticeable enantio-selectivity. Our results support and extend structural models based upon Norden's studies, and conflict with Barton's model.     

Room Temperature Phosphorescence pH Switch Based on Photo-induced Electron Transfer

In this paper, photoinduced electron transfer(PET)phosphoroionophore,N-(1-bromo-2-naphthylmethyl)-dicthanolamine (BND)was synthesized and its phosphorescent characteristics were studied,The experimental results showed that strong phosphorescence could be observed in β-cyclodextrin apueous solution only at low pH value ,This system combined AND and NOT function to produce a three-input inhibit (INH)logic gate .     

Effect of dextran molecular weight on resonance light-scattering of quantum dots modified with dextran and concanavalin A

The reversible aggregation between dextran-conjugated CdSe quantum dots(Dex-CdSe-QDs) and concanavalin A(Con A) was explored based on the specific affinity of polysaccharide for Con A by resonance light-scattering technique.In this study,the aggregation of Dex-CdSe-QDs induced by Con A and sequential dissociation by glucose was determined over a wide range of dextran molecular mass(10-500 kDa).The results demonstrate that the sensitivity of lectin-dextran-modified-QDs interactions increase with dextran molecular mass,and an optimum dextran molecular mass is 500 kDa.     

Theoretical studies of adsorption property on Ir_4/MgO and Ir_4/γ-Al_2O_3

The adsorption properties of atomic and molecular species on Ir4/MgO and Ir4/γ-Al2O3 have been systematically studied by means of planewave density functional theory(DFT)calculations using the periodic boundary conditions.The binding energies of these species were ordered as follows:H2O相似文献