Reactions with dimethylformamide‐dimethylacetal: Synthesis and reactions of several new pyridine and pyrazolo[3,4‐b]pyridine derivatives

6‐Aminopyridine‐2(1H)‐thiones 1a,b reacted with dimethylformamide‐dimethylacetal (DMF‐DMA) to give the corresponding 6‐{[(N,N‐dimethylamino)methylene]amino}pyridine derivatives 2a,b . The latter compounds reacted with hydrazine hydrate to afford the 3,6‐diamino‐1H‐pyrazolo[3,4‐b]pyridine derivative 4 and 3‐amino‐5‐hydrazino‐1H‐pyrazolo[4′,3′:5,6]pyrido[2,3‐d]pyrimidine derivative 7 , respectively. Compound 4 condensed with DMF‐DMA to yield the 3,6‐bis{[(N,N‐dimethylamino)methylene]amino}‐1H‐pyrazolo[3,4‐b]pyridine derivative 10 , which reacted with malononitrile to give the corresponding pyridopyrazolopyrimidine derivative 15 . © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:399–404, 2007; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20312     

Transport properties of thermoplastic/thermoset blends

Gas transport properties are reported for two series of films prepared from initially miscible thermoplastic/thermoset blends, respectively, polystyrene PS/thermoset and poly(2,6 dimethyl 1,4 phenylene oxide) PPE/thermoset blends. The thermoplastic contents are such that in both cases, after the phase separation, the continuous phase is the thermoplastic‐rich phase and scanning electron microscopic photomicrographs clearly evidenced the dispersion of thermoset‐rich nodules in the continuous thermoplastic‐rich phase with a more tortuous morphology in the case of PPE based films. Permeability measurements were made for O₂ and CO₂ at 20°C and a reduction in permeability coefficients was observed with increased thermoset content. Analysis using Maxwell law suggests that for all thermoplastic/thermoset blends, the thermoset particles can be considered as impermeable to gas and that the diffusion takes place in the continuous phase. In the case of PPE based films, the higher decrease of permeability than that predicted by the law has been related to the morphology of the blends and thus the tortuosity and to a partial miscibility of the thermoset in the thermoplastic. © 1999 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 37: 473–483, 1999     

Synthesis of polyurethane acrylate oligomers based on polybutadiene polyol

Polyurethane acrylate oligomers (PUA) were prepared by a competitive reaction of 4,4′-dicyclohexyl methane diisocyanate (H₁₂MDI) with hydroxy terminated polybutadiene (HTPB) and hydroxyethylacrylate (HEA). Kinetic models were established for noncatalytic and catalytic systems, and the reaction constants were calculated using a numerical method. The evolution of the noncatalyzed and catalyzed reactions were analyzed, respectively, by SEC and FTIR. Comparing the reactivities of HTPB and HEA, as well as other small molar mass model alcohols, the HTPB showed the higher reactivity. HTPB is 700 times more reactive than HEA at 80°C. This high reactivity was analyzed as a result of lower concentration of hydrogen bonds in bulk HTPB. The activation energy of the noncatalyzed and catalyzed reactions were found to be, respectively, 56.98 and 45.16 KJ/mol. The structures of the PUA synthetized in one-step or two-step process were analyzed and discussed using a gelation model and the kinetic data obtained. © 1996 John Wiley & Sons, Inc.     

Clavulazols A and B,Two New Pyrazine Derivatives from Clavularia Viridis

Two new marine pyrazine derivatives, clavulazols A ( 4 ) and B ( 5 ), were isolated from ethyl acetate extract of the soft coral Clavularia viridis collected in Taiwan. The structures were determined on the basis of spectral analysis, especially 2D NMR as well as chemical conversion.     

Selecting optimum maintenance strategy by fuzzy interactive linear assignment method

In the current competitive environment managers of manufacturing and service organizations try to make their organizations competitive by providing timely delivery of high quality products. Maintenance, as a system, plays a key role in reducing cost, minimizing equipment downtime, improving quality, increasing productivity and providing reliable equipment and as a result achieving organizational goals and objectives. This paper presents a new approach for selecting optimum maintenance strategy using qualitative and quantitative data through interaction with the maintenance experts. This approach has been based on linear assignment method (LAM) with some modifications to develop interactive fuzzy linear assignment method (IFLAM).     

A new effective potential for deuteron

We calculate for the first time the static properties of the deuteron, within the framework of supersymmetric quantum mechanics, analytically. A new effective potential and its partner are derived from a superpotential so that all parameters are fitted by the experimental data. An analytical expression is obtained for the deuteron wave function and contributions of the orthogonal ¹³S₁ and ¹³D₁ states are determined, explicitly. Compared to one pion exchange, the superpotential produces an electrostatic as well as two pion exchange terms for the potential. The saddle point radius of the potential and the maximum of the wave function are linearly proportional. In comparison with other methods, the approach presented in this paper is a new and extensible symmetry-based approach that, despite its straightforward calculations and explicit analytical expressions, provides a good explanation for two-body effective interactions such as two-nucleon systems and diatomic molecules.     

A comparative study between classical stirred and ultrasonically-assisted dead-end ultrafiltration

The aim of this work was to determine mass transfer coefficients in the cases of ultrasonically-assisted and classical stirred dead-end ultrafiltration. A comparative study was then performed, and mass transfer coefficients obtained under ultrasonic conditions are described by an empirical model. This correlation results from an analogy with what is observed using a stirred cell and involves the ultrasonic power as the main parameter. The hydrodynamics are assumed to depend on the intensity of the ultrasound effects illustrated by the agitation arising within the cell. This agitation is due to convective currents as well as physical effects due to cavitation. The concentration polarization phenomenon is therefore affected by this action of ultrasonic waves.     

One-step Synthesis of PCL-Urethane Networks using a Crosslinking/de-crosslinking Agent

Thermally reversible cross-linked polycaprolactone-urethane (PCL-U) was prepared in one-step procedure. The PCL-U networks were synthesized from a di-isocyanate (4,4′-methylene bis(cyclohexylisocyanate) (HMDI) and hydroxyl bearing macromers and monomers: hydroxy-terminated PCL, glycerol and a di-alcohol Diels-Alder (DA) adduct. This adduct was used to introduce both diene and dienophile functions in the structure and also to protect the maleimide functions from polymerization. The thermoresponsive behavior of the material was characterized by commonly used methods such as solubility tests at different temperatures and differential scanning calorimetry analyses to highlight rDA reactions and also by rheological analysis. The effects of the cooling rate, the molar mass of polycaprolactone as well as the molar ratio [di-Isocyanate]/[PCL-diol] on the cross-linking/de-cross-linking temperatures were also analyzed. The reversible networks obtained have a self-healing behavior.     

Flight dynamics and control of flapping-wing MAVs: a review

This paper provides a thorough review of the significant work done so far in the area of flight dynamics and control of flapping-wing micro-air-vehicles (MAVs). It provides the background necessary to do research in that area. Furthermore, it raises questions that need to be addressed in the future. The three main blocks constituting the flight dynamic framework of flapping MAVs are reviewed. These blocks are the flapping kinematics, the aerodynamic modeling, and the body dynamics. The design and parametrization of the flapping kinematics necessary to produce high-control authority over the MAV, as well as design of kinematics suitable for different flight conditions, are reviewed. Aerodynamic models used for analysis of flapping flight are discussed. Particular attention is given to the physical aspects captured by these models. The issues and consequences of averaging the dynamics and neglecting the wing inertia are discussed. The dynamic stability analysis of flapping MAVs is usually performed by either averaging, linearization and subsequent analysis or using Floquet theory. Both approaches are discussed. The linear and nonlinear control design techniques for flapping MAVs are also reviewed and discussed.     

The Impacts of Different Biological Treatments on the Transformation of Explosives Waste Contaminated Sludge

The dinitrotoluene isomers 2,4 and 2,6-dinitrotoluene (DNT) represent highly toxic, mutagenic, and carcinogenic compounds used in explosive manufacturing and in commercial production of polyurethane foam. Bioremediation, the use of microbes to degrade residual DNT in industry wastewaters, represents a promising, low cost and environmentally friendly alternative technology to landfilling. In the present study, the effect of different bioremediation strategies on the degradation of DNT in a microcosm-based study was evaluated. Biostimulation of the indigenous microbial community with sulphur phosphate (2.3 g/kg sludge) enhanced DNT transformation (82% transformation, from 300 g/L at Day 0 to 55 g/L in week 6) compared to natural attenuation over the same period at 25 °C. The indigenous microbial activity was found to be capable of transforming the contaminant, with around 70% transformation of DNT occurring over the microcosm study. 16S rDNA sequence analysis revealed that while the original bacterial community was dominated by Gammaproteobacteria (30%), the addition of sulphur phosphate significantly increased the abundance of Betaproteobacteria by the end of the biostimulation treatment, with the bacterial community dominated by Burkholderia (46%) followed by Rhodanobacter, Acidovorax and Pseudomonas. In summary, the results suggest biostimulation as a treatment choice for the remediation of dinitrotoluenes and explosives waste.