辐照诱导的人正常肝细胞系HL-7702细胞延迟效应

利用X射线辐照人正常肝细胞系HL-7702细胞, 运用胞质分离阻滞微核法实验检测细胞微核率,AnnexinV FITC细胞凋亡检测试剂盒检测细胞凋亡率, 细胞微核率和凋亡率随着辐照剂量的增加而显著增加。X射线照射后细胞传代培养, 第7代时不同剂量辐照后子代细胞微核率和凋亡率同未辐照细胞相比已无明显区别。 对不同剂量辐照后传代7代的细胞再次照射2.5 Gy的相同剂量,发现它们细胞微核率和凋亡率存在明显差异,即初次受辐照剂量高的细胞, 再次以相同剂量辐照后的微核率和凋亡率也高. 这些结果表明,X射线辐照导致了HL-7702细胞基因组不稳定性这一辐射延迟效应,再次辐照使得辐射的延迟效应得以明显的表现。 Human normal liver cell line HL-7702 cells were irradiated with different doses of X rays. Micronucleus and apoptosis rates in the irradiated cells were measured with cytokinesis block micronucleus method and Annexin V FITC apoptosis detection kit, respectively. Experimental data showed that the micronucleus and apoptosis rates increased obviously with increasing irradiation dose. After seven population doublings, the micronucleus and apoptosis rates of the cells surviving exposure to the X rays reduced to the same levels as non irradiated control cells; the progenies of the cells were secondly exposed to X rays at the same dose of 2.5 Gy. We found that the progenies of the cells surviving the first irradiations of the various doses showed markedly differential micronucleus frequencies and apoptotic rates. Although the same dose of 2.5 Gy was applied in the second irradiations, the micronucleus frequencies and apoptotic rates of the progenies of the cells initially exposed at higher doses were significantly higher than the others. These results indicate that X rays lead to genomic instability in HL 7702 cells, which is an important manifestation of radiation induced delayed effect, and a second radiation stimulus makes the delayed effect in the progeny of the previously irradiated cells be expressed obviously.     

针对特定场合的图像恢复算法实验研究

介绍了数字图像恢复技术的原理和主要的恢复算法,针对离焦退化、运动退化和高斯退化等不同应用场合,结合各种评价函数分析比较了维纳滤波、约束最小二乘法、Lucy-Richardson和最大熵法在图像恢复中的各自特点。对实际拍摄的离焦模糊图片进行了恢复处理,比较和印证了各算法的特性。总结了各算法在图像恢复中的特点以及各种图像质量评价函数的适用范围。     

R141b喷射式制冷系统的喷射器热力学模型设计

本文采用传统的热力学模型,理论设计了对制冷剂R141b适用的喷射器,通过计算机程序及优化设计理论设计出该喷射器.同时,背压是整个循环中的重要参数,过高的背压会影响喷射器的性能,本文还给出喷射器的最大背压计算方法,以此来设计出最适合整个工况运行的冷凝器,从而完成整个循环的设计.     

Nd:YAG激光器光栅式扫描预处理的计算模拟与优化分析

 采用计算模拟的方法,研究了光栅式扫描预处理的扫描方式以及脉冲能量波动、定位误差对预处理效率的影响。研究发现,脉冲能量波动及其定位误差使预处理效率降低,同时其影响与扫描方式之间存在相互调制作用,因此可以通过选择合适的扫描方式以及扫描间隔来优化预处理流程,提高预处理效率。此外发现,光斑呈等边三角形排列时的预处理效率优于正方形。     

Effect of Aspect Ratio Distribution on Localized Surface Plasmon Resonance Extinction Spectrum of Gold Nanorods

Gold nanorods with different aspect ratios are prepared in micells using a seeded growth method. Their extinction spectra are observed with an UV-visible spectrophotometer and analysed theoretically. It is known that there are two plasmon resonance peaks for gold nanorod corresponding to transverse and longitudinal plasmon resonance respectively. Moreover, the longitudinal plasmon resonance peak shifts to long wavelength when we increase the aspect ratio determined from TEM. Especially, we model the extinction spectrum using Gans' theory and compare it with our experimental result. Considering the aspect radios distribution of gold nanorods, it is found that longitudinal plasmon resonance peak will be wider than the nanorods with single aspect ratio, which is consistent with our experimental result. In addition, the effect of dielectric constant of surrounding medium is considered.     

基于视频的精确放疗摆位系统研究

重点介绍了中国科学院等离子体物理研究所“精确放射治疗系统”课题组在基于视频的摆位方法领域的最新研究成果,如基于双目视觉的摆位系统、基于轮廓匹配的位置测量系统和呼吸门控系统。简要介绍了这些方法的原理、应用场合及应用前景。This paper introduces the newest research production on patient positioning method in accurate radiotherapy brought by Accurate Radiotherapy Treating System （ARTS） research team of Institute of Plasma Physics of Chinese Academy of Sciences, such as the positioning system based on binocular vision, the position-measuring system based on contour matching and the breath gate controlling system for positioning. Their basic principle, the application occasion and the prospects are briefly depicted.     

Single Qubit and Its Universal Logic Gate Made of a Heisenberg Spin Cluster with Five Particles

We investigate an anisotropic Heisenberg spin cluster with five particles controlled by a time-dependent magnetic field. With the algebraic dynamical method, we obtain the exact analytical solution to the time dependent Schr6dinger equation. Based on the analytical solution, it is shown that the system can be used as a universal single qubit logic gate controlled by the strength and frequency of the magnetic field, and the six special single qubit logic gates can be realized physically. We also discuss the anti-decoherence property of the qubit and its logic gates resulted from particle coupling effect and collectivity of the cluster.     

非线性拉曼激光雷达测量CO2气体的研究

提出了利用气体的受激拉曼散射(SRS)效应激光雷达光源来探测大气中的CO2气体的新方法,设计出探测大气中CO2气体含量的非线性拉曼增益激光雷达,用Nd:YAG激光器(1064 nm)的三倍频光(354.7 nm)通过分别装有CO2气体和N2气体的拉曼管,分别得到CO2气体和N2气体的受激拉曼散射的一阶斯托克斯线(S1),并用S1线作为雷达的种子发射光源.通过实验得到拉曼管中的气压与S1能量的变化关系,对其优化条件和物理机制进行了分析.该实验方法已经成功测出了大气中CO2气体的回波电压信号.     

空间目标红外辐射特性研究

利用目标的红外光谱特性进行目标探测和识别是一种有效的方法。以空间卫星为目标,研究了其红外辐射特性形成的机理;利用所建立的数学模型,仿真了空间目标在探测面上所形成的红外光谱特性曲线;分析了模型中各参数对目标光谱特性的影响程度和卫星目标的红外光谱曲线。     

基于伽利略结构的二级激光扩束系统的设计

针对高倍率扩束系统设计要求(即轴上和轴外像差都得到较好的校正),从三级像差理论出发,设计了一种新型的40^×高倍率激光扩束系统。该系统是基于简单的伽利略结构并通过二级扩束系统来实现的,系统包括4片透镜,通过引入2个二次非球面、 2个反射镜或1个棱镜来折叠光路。利用CODE V光学设计软件给出了该系统的光学结构参数和外形结构图,并进行了像质评价。结果表明：该系统结构简单,设计难度小,成本较低,像质好,性能优良,是一种可以被广泛采用的高倍率激光扩束系统。