Cu(I) catalyst in DMF: an efficient catalytic system for the synthesis of furans from 2-(1-alkynyl)-2-alken-1-ones

The cyclization of 2-(1-alkynyl)-2-alken-1-ones 1 proceeded very smoothly in the presence of alcohols 2 with a catalytic amount of Cu(I)Br in DMF at 80 degrees C, leading to the formation of highly substituted furans 3. The catalytic system reported herein is easy to handle, compared to the previously known system wherein the reaction between 1 and 2 needed to use moisture sensitive gold(III) chloride.     

深圳市1408例儿童发中钙,铁,镁含量调查与分析

用火焰原子吸收法检测了深圳市１４０８例１３岁以下儿童发中钙，铁，镁的元素含量，并探讨了元素含量与年龄，性别的关系，结果显示，性别差异有显著意义，钙，镁含量随年龄增长有相似变化。     

The Photochemistry of Diazomethane the Reactions of Methylene with Toluene and P-Xylene in Liquid Phase (I)

The photochemistry of diazomethane in toluene and p-xylene solutions was investigated. The reactions of methylene with toluene gave eight products. In the diazomethane p-xylene solution, p-ethyltoluene, 1,2,4-trimethylbenzene, 1,4-dimethylcyclohepatriene-1,3,5 and three unidentified compounds were found as products of the reaction of methylene with p-xylene. The relative rates of addition and insertion reaction of methylene with toluene and p-xylene have been calculated.     

Enantioselective Addition of Iodine Azide to α,β-Unsaturated Carboxylic Acid Derivatives

The addition of iodine azide to chiral conjugated N-enoyl-sultam or α,β-unsaturated N-acyloxazolidinones generated two asymmetric centers at C(α) and C(β) with high π-face differentiation and regioselectivity. The diastereomerically pure product was easily obtained by crystallization with purity up to 94% de. The structure of 2a was determined by X-ray diffraction analysis which also indicated that B and 4 are reactive conformations.     

The RS-.HSR Hydrogen Bond: acidities of alpha,omega-dithiols and electron affinities of their monoradicals

Gas-phase acidities (deltaGo(acid)) have been measured for 1,2-ethanedithiol, 1,3-propanedithiol, and 1,4-butanedithiol, using a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. Adiabatic electron affinities (EAs) of the thiolate monoradicals of these compounds were assigned from electron photodetachment spectra of their corresponding thiolate monoanions, acquired using a cw-ICR. The dithiols exhibit enhanced acidities (up to 8.7 kcal/mol in deltaGo(acid)) and greater EAs (up to 6.7 kcal/mol) than analogous monothiol species. These differences are attributed to an intramolecular RS-.HSR hydrogen bond in the thiolate anion. Considerations of the RO-.HOR hydrogen bond in monoanions of alpha,omega-diols and in the [CH(3)O-.HOCH(3)] complex anion suggest that the RS-.HSR hydrogen bond provides up to 9 kcal/mol extra stabilization.     

Theoretical study of the effect of frit quality on chromatography using computational fluid dynamics

Summary Frits at both ends of a chromatographic column, especially for a preparative column, have significant influence on the flow distribution within the column and thus the column efficiency. However, frits have received little attention from chromatographers in the past. Here a theoretical study was conducted with the aid of CFD software FLUENT to investigate the effect of frits on the performance of homogeneous and heterogeneous chromatographic columns. A dimensionless number,FQ, was applied to characterize frit quality. This study visualized how frit quality affects the flow distribution and the concentration band, the shape of eluted pulse at the colum exit and column efficiency. Simulation results show that the development length of the flow distribution is related toFQ but has nothing to do with the packing heterogeneity. The curvature of the concentration band in a column depends onFQ and packing quality. This study shows column efficiency can be improved significantly by increasingFQ and/or frit permeability.     

超高交联吸附树脂吸附对硝基苯乙酮的热力学研究

比较两种超高交联聚苯乙烯吸附树脂NJ-8、AM-1与Amberlite XAD-4(以下简称XAD-4)对对硝基苯乙酮的静态吸附行为，根据吸附等温线研究了吸附热力学性质．在298～318K和研究的浓度范围内，NJ-8，AM-1、XAD-4对对硝基苯乙酮的吸附平衡数据符合Freundlich吸附等温方程．结果表明：吸附为放热过程，适当降低温度有利于吸附．计算了对硝基苯乙酮在NJ-8，AM-1、XAD-4树脂上的吸附焓变、自由能变，吸附熵变．对吸附行为作了合理的解释。     

Isoochotensine,a New Spirobenzyusoquinoline Alkaloid from: Corydalis Ochotensis Turcz

Separation of the phenolic fraction of Corydalis ochotensis afforded a new spirobenzylisoquinoline alkaloid, isoochotensine ( 1 ) and three known alkaloids, ochotensine ( 3 ), cheilanthifoline ( 7 ), and lienkonine ( 9 ) as their acetyl derivatives together with a known nonphenolic alkaloid, ochotensimine ( 5 ). Their structures were elucidated by the spectral data.     

Comparative Study on the Structure of Water in Reverse Micelles Stabilized with Sodium Bis(2-ethylhexyl) Sulfosuccinate or Sodium Bis(2-ethylhexyl) Phosphate in n-Heptane

The microstructure of water solubilized in H(2)O/surfactant/n-heptane ternary systems has been investigated by employing (1)H-NMR and FT-IR spectroscopic techniques. Two reverse micellar systems were prepared and studied, i.e., sodium bis(2-ethylhexyl) sulfosuccinate in n-heptane (H(2)O/AOT/n-heptane) and sodium bis(2-ethylhexyl) phosphate in n-heptane (H(2)O/NaDEHP/n-heptane). (1)H-NMR data showed that the chemical shift of water protons for the AOT and NaDEHP reverse micelles varied downfield and upfield, respectively, with an increase of the water content. The opposite shift directions with increasing water content are interpreted as due to a composition change of the solubilized water associated with head-groups and sodium counterions in reverse micellar systems. On the basis of deconvolution results of FT-IR spectra, a four-component model is proposed to interpret the FT-IR and (1)H-NMR results. Copyright 2000 Academic Press.     

When does gradient Ricci soliton have one end?

Annals of Global Analysis and Geometry - In this paper, we study a problem of finding compact hypersurfaces of prescribed mean curvature with free boundary in a ball. We transform the problem to an...