Crystal and molecular structure of 1R,3S,5S,7R,10R-3,6,6,10,14-Pentamethyltricyclo[10.3.0.05,7]pentadeca-11,14-diene-1, 10-dihydroxy-2,13-dione (Japodagrol), C20H28O4

A new cytotoxic macrocyclic diterpenoid named Japodagrol, C₂₀H₂₈O₄, has been isolated from the ornamental plantJatropha podagrica, family Euphorbiaceae, grown in Nigeria. The structure of the title compound, C₂₀H₂₈O₄, was solved by X-ray analysis.M _r =332.44, monoclinic space groupC2,a=23.285(4),b=6.5105(12),c=12.505(3) Å,=98.504(17),V=1874.8 ų,Z=4,D _c =1.178 Mg/m³. CuK radiation (graphite crystal monochromator, =1.54184 A), (CuK)=6.13 cm^–1,F(000)=720,T=290 K. Final conventionalR factor=0.035,R _w =0.038 for 3349 observed reflections. The structure was solved with the programDirdif. The 5-membered ring is closed to a half-chair form. The compound contains inter- and intramolecular hydrogen bonds.     

Drag on an elliptic cylinder in a fluid particle suspension

An elliptic cylinder is performing oscillations parallel to either of the principal axes of the cross-sectional ellipse in a fluid particle suspension. The stream function governing the flow and the velocity components are determined in terms of Mathieu functions. The drag on the cylinder is evaluated and expressed in terms of two parametersK andK. The effects of the variation of the frequency parameter, eccentricity parameter and relaxation time parameter on the drag parametersK, K is studied numerically.     

Estimate of a polynomial in generalized exponential functions in the convex hull of two domains

Пусть $$f_n (z) = \exp \{ \lambda _n z\} [1 + \psi _n (z)], n \geqq 1$$ гдеψ _n (z) — регулярны в н екоторой односвязно й областиS, λ _n — нули целой функц ии экспоненциальног о ростаL(λ) с индикатрис ой ростаh(?), причем $$|L\prime (\lambda _n )| > C(\delta )\exp \{ [h(\varphi _n ) - \varepsilon ]|\lambda _n |\} \varphi _n = \arg \lambda _n , \forall \varepsilon > 0$$ . Предположим, что на лю бом компактеK?S $$|\psi _n (z)|< Aq^{|\lambda |_n } , a< q< 1, n \geqq 1$$ гдеA иq зависит только отK. Обозначим через \(\bar D\) со пряженную диаграмму функцииL(λ), через \(\bar D_\alpha \) — смещение. \(\bar D\) на векторα. Рассмотр им множестваD ₁ иD ₂ так ие, чтоD ₁ иD ₂ и их вьшуклая обо лочкаE принадлежатS. Пусть \(\bar D_{\alpha _1 } \subset D_1 , \bar D_{\alpha _2 } \subset D_2 \) Доказывается, что сущ ествует некоторая об ластьG?E такая, что \(\mathop \cup \limits_{\alpha \in [\alpha _1 ,\alpha _2 ]} \bar D_\alpha \subset G\) и дляz∈G верна оценка $$\sum\limits_{v = 1}^n {|a_v f_v (z)|} \leqq B\max (M_1 ,M_2 ), M_j = \mathop {\max }\limits_{t \in \bar D_j } |\sum\limits_{v = 1}^n {a_v f_v (t)} |$$ , где константаB не зав исит от {a _v }.     

Latency of auditory brain-stem responses and otoacoustic emissions using tone-burst stimuli

A comparison of the latency of auditory brain-stem responses (ABR) and evoked otoacoustic emissions (EOAE) has led to an interpretation for the travel of transients in the peripheral auditory system that is consistent with both sets of data. The "cochlear echo" theory for the origin of the EOAE indicates that the latency of a particular frequency component back to the ear canal should be twice the forward latency of its characteristic place in the cochlea. The latency of wave V of the ABR to tone-burst stimuli can be described as the sum of two components: (1) a component that varies with intensity and frequency in an orderly and predictable manner and (2) a component that is independent of both intensity and frequency. Because the EOAE data can be predicted by taking twice the value of component (1) of the ABR latency, this component is interpreted to be due to mechanical travel through the cochlea. A consequence of this interpretation is that the remaining neural component of the ABR latency must be relatively independent of frequency and intensity.     

Asymptotic behavior of the spectrum of certain problems,connected with the oscillation of fluids

One obtains the principal term of the asymptotics of the spectrum in a series of problems of the theory of small oscillations of fluids, filling partially a container. First one discusses a certain problem of general character, the nonlocal Steklov type problem. The considered problems are connected with the oscillations of a capillary ideal (or capillary stratified) fluid, of a heavy viscous fluid, of a capillary viscous fluid, and with the oscillations of a fluid in container with an elastic bottom.Translated from Zapiski Nauchnykh Seminarov Leningradskogo Otdeleniya Matematicheskogo Instituta im. V. A. Steklova AN SSSR, Vol. 152, pp. 158–164, 1986.The author is deeply grateful to her scientific advisor M. Sh. Birman. The author is grateful also to N. D. Kopachevskii for his interest in the paper.     

On the width of an orientation of a tree

There are 2 ^n-1 ways in which a tree on n vertices can be oriented. Each of these can be regarded as the (Hasse) diagram of a partially ordered set. The maximal and minimal widths of these posets are determined. The maximal width depends on the bipartition of the tree as a bipartite graph and it can be determined in time O(n). The minimal width is one of [/2] or [/2]+1, where is the number of leaves of the tree. An algorithm of execution time O(n + ² log ) to construct the minimal width orientation is given.This research was partially funded by the National Science and Engineering Research Council of Canada under Grant Number A4219.     

Schedule-an expert-like system for machine scheduling

The construction of an expert-like system for machine scheduling called SCHEDULE is presented. Essential parts of SCHEDULE were developed by students in a laboratory course Operations Research on Microcomputers at the University of Karlsruhe, Germany. SCHEDULE consists of the components data base, knowledge base, inference engine, explanation facility, dialog component, and knowledge acquisition component. The knowledge base contains an algorithm base for solving different types of scheduling problems. To establish the rules of the knowledge base the well-known three-field classification of deterministic machine scheduling problems and the concept of the reduction digraph are exploited. Experiences gained during building and demonstrating SCHEDULE are reported.     

Spectroscopic factors of9Be,10B and13C from (d,t) reactions

The differential cross sections of tritons from the (d, t) reaction on⁹Be,¹⁰B and¹³C targets have been measured in the angular range of 5° _LAB110° with relatively small errors, 5%. The experimental data were analysed in terms of the standard DWBA using both zero-range and exact finite-range approaches.     

Size distribution of fractured areas in one-dimensional systems

We study a one-dimensional model for fracture, identifying fractured areas with intervals on which a stress field exceeds a threshold value. When is a diffusion process, the cumulative numberN(l) of fractured areas whose length is greater thanl obeys a power lawCl ^–p asl0 with probability one. The exponentp and the constantC are determined. The exponentp agrees with the Hausdorff dimension of the end points of fractured areas, i.e., ^–1(). Even if is self-similar with parameterH>0, i.e.,(cx)– is equivalent toc ^H {(x)–} for anyc>0, the exponentp does not depend solely onH;p=H, where(0, 1/H) is another parameter characterizing. Non-diffusion processes are given whereN(l) does not follow a power law.     

The velocity correlation function for the Lorentz gas

The results of variational solutions of the repeated ring and self-consistent repeated ring equations for the two-and three-dimensional overlapping Lorentz gas (LG), as formulated in a previous report, are presented. Calculations of the full velocity correlation function (VCF) for the 2D LG, including long-time tails, are compared with those from molecular dynamics. The trial functions chosen lead to predictions for the long-time tails that improve as the density of the scatterers is increased. At a value of 0.24 for* (= ², where is the density and the radius of scatterers), the self-consistent amplitudes of the long-time tail are within 40% of the molecular dynamics. A limited number of 3D results for the short-time behavior of the repeated ring VCF are presented. The 3D solutions agree with the molecular dynamics to within 10%.