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401.
High-order optical harmonic generation from solid surfaces 总被引:1,自引:0,他引:1
During the interaction of an intense ultrashort laser pulse with solid targets, a thin layer of surface plasma is generated in which the density drops to the vacuum level in a distance much shorter than the wavelength. This sharp plasma-vacuum boundary performs an oscillatory motion in response to the electromagnetic forces of the intense laser light. It is shown that the generation of reflected harmonics can be interpreted as a phase modulation experienced by the light upon reflection from the oscillating boundary. The modulation side-bands of the reflected frequency spectrum correspond to odd and even harmonics of the laser frequency. Retardation effects lead to a strong anharmonicity for high velocities of the plasma-vacuum boundary. As a result, harmonic generation is strongly enhanced in the relativistic regime of laser intensities.Prof. F. P. Schäfer on the occasion of his 65th birthday. 相似文献
402.
We study the arguments given in [ 1 ] which suggest that the uplifting procedure in the KKLT construction is not valid. First we show that the modification of the SUSY breaking sector of the nilpotent superfield, as proposed in [ 1 ], is not consistent with non‐linearly realized local supersymmetry of de Sitter supergravity. Keeping this issue aside, we also show that the corresponding bosonic potential does actually describe de Sitter uplifting. 相似文献
403.
Svend Borup Jensen Lotte Studsgaard Meyer Nikolaj Schandorph Nielsen Sren Steen Nielsen 《Molecules (Basel, Switzerland)》2022,27(13)
Technetium-99m macroaggregated albumin ([99mTc]Tc-MAA) is an injectable radiopharmaceutical used in nuclear medicine for lung perfusion scintigraphy. After changing to a new batch of macroaggregated albumin (MAA), we saw unwanted uptake in the liver and spleen. The batch was therefore tested by both the supplier and us and we found it to comply with the requirements of the European Pharmacopoeia (Ph. Eur.). However, a simple comparison between the problematic batch and a batch supplied by another manufacturer showed that there was a significant difference. The quality testing showed a higher number of small particles in the problem encumbered MAA batch with unwanted in vivo uptake. In this article we present a simple method of testing for particle size of [99mTc]Tc-MAA, which gives a good indication of how the radioactive drug performs in vivo. We argue that the quality control method described in the Ph. Eur. should be changed. The changes will improve concordance between the laboratory analyzes and what is seen in vivo in human lung perfusion scintigraphy. Furthermore, we hope that the MAA suppliers without delay will replace their release procedure to be in accordance with the method described in this article. 相似文献
404.
Aage Kristian Olsen Alstrup Svend Borup Jensen Ole Lerberg Nielsen Lars Jdal Pia Afzelius 《Molecules (Basel, Switzerland)》2021,26(14)
The development of new and better radioactive tracers capable of detecting and characterizing osteomyelitis is an ongoing process, mainly because available tracers lack selectivity towards osteomyelitis. An integrated part of developing new tracers is the performance of in vivo tests using appropriate animal models. The available animal models for osteomyelitis are also far from ideal. Therefore, developing improved animal osteomyelitis models is as important as developing new radioactive tracers. We recently published a review on radioactive tracers. In this review, we only present and discuss osteomyelitis models. Three ethical aspects (3R) are essential when exposing experimental animals to infections. Thus, we should perform experiments in vitro rather than in vivo (Replacement), use as few animals as possible (Reduction), and impose as little pain on the animal as possible (Refinement). The gain for humans should by far exceed the disadvantages for the individual experimental animal. To this end, the translational value of animal experiments is crucial. We therefore need a robust and well-characterized animal model to evaluate new osteomyelitis tracers to be sure that unpredicted variation in the animal model does not lead to a misinterpretation of the tracer behavior. In this review, we focus on how the development of radioactive tracers relies heavily on the selection of a reliable animal model, and we base the discussions on our own experience with a porcine model. 相似文献
405.
Tiago Alves Castro Bruna Santos Leite Larissa Santos Assuno Tayane de Jesus Freitas Nelson Barros Colauto Giani Andrea Linde Deborah Murowaniecki Otero Bruna Aparecida Souza Machado Camila Duarte Ferreira Ribeiro 《Molecules (Basel, Switzerland)》2021,26(23)
Most dyes used in the food industry are synthetic and can be a health hazard. Red tomato may serve as a natural alternative dye to replace synthetic colorants. This study aimed to review the literature on the addition of red tomato products (powder tomato, paste, freeze-dried, tomato peel powder, tomato pomace) to reduce the usage of synthetic dyes in the food industry. Red tomato products have been used as coloring in pasta, bologna, sausages, cookies, crackers, macaroons, hamburgers, breads, muffins, cheeses, and nuggets. The trans-cis isomerization of lycopene by oxidative processes directly affects the color of the pigment. The lycopene contained in tomato has antioxidant activity and could reduce or eliminate other oxidants and/or synthetic preservatives in food. Moreover, tomatoes in foods have high sensory scores, nutritional appeal, and marketing potential. However, its use as a food colorant has been not extensively explored. Therefore, further studies are still required, especially on the stability of carotenoids in tomatoes used in processed foods. 相似文献
406.
Lars Jdal Pia Afzelius Aage Kristian Olsen Alstrup Svend Borup Jensen 《Molecules (Basel, Switzerland)》2021,26(11)
Introduction: Radiotracers are widely used in medical imaging, using techniques of gamma-camera imaging (scintigraphy and SPECT) or positron emission tomography (PET). In bone marrow infection, there is no single routine test available that can detect infection with sufficiently high diagnostic accuracy. Here, we review radiotracers used for imaging of bone marrow infection, also known as osteomyelitis, with a focus on why these molecules are relevant for the task, based on their physiological uptake mechanisms. The review comprises [67Ga]Ga-citrate, radiolabelled leukocytes, radiolabelled nanocolloids (bone marrow) and radiolabelled phosphonates (bone structure), and [18F]FDG as established radiotracers for bone marrow infection imaging. Tracers that are under development or testing for this purpose include [68Ga]Ga-citrate, [18F]FDG, [18F]FDS and other non-glucose sugar analogues, [15O]water, [11C]methionine, [11C]donepezil, [99mTc]Tc-IL-8, [68Ga]Ga-Siglec-9, phage-display selected peptides, and the antimicrobial peptide [99mTc]Tc-UBI29-41 or [68Ga]Ga-NOTA-UBI29-41. Conclusion: Molecular radiotracers allow studies of physiological processes such as infection. None of the reviewed molecules are ideal for the imaging of infections, whether bone marrow or otherwise, but each can give information about a separate aspect such as physiology or biochemistry. Knowledge of uptake mechanisms, pitfalls, and challenges is useful in both the use and development of medically relevant radioactive tracers. 相似文献
407.
Linde H Velarde MG Waldhelm W Wierschem A 《Journal of colloid and interface science》2001,236(2):214-224
Collisions and reflections of solitary waves and (periodic) wave trains driven by surface tension gradients (Marangoni stresses) exhibit a wealth of astonishing features. Depending on the angle between the incoming wave crests, the outgoing waves show in their trajectories after collision negative phase shift for small enough angles, no phase shift at about pi/2 and hence no appreciable change in their trajectories, or positive phase shift, accompanied by the appearance of a phase-locked third wave or Mach-Russell stem at wider crossing angles. Synchronous wave collisions exhibit regular but complex dynamic network patterns whose formation and dependence on the size and the shape of the container are discussed. Although wave reflections share some of these features, corresponding apparently to the outcome of the virtual collision of a wave with its mirror image, there are significant differences that are described here. Copyright 2001 Academic Press. 相似文献
408.
Posthumus W Laven J de With G van der Linde R 《Journal of colloid and interface science》2006,304(2):394-401
The effect of the addition of antimony doped tin oxide (ATO) nanoparticles on the electrical conductivity of acrylate films is described. To enable dispersing of ATO in acrylate matrices, 3-methacryloxypropyltrimethoxysilane (MPS) was grafted on the surface of the filler. The amount of MPS used for this surface modification was found to strongly affect the electrical conductivity. Surface modification with a large amount of MPS resulted in colloidally stable dispersions of ATO, leading to a homogeneous distribution. Surface modification with small amounts of MPS led to instable ATO dispersions and aggregation of ATO into a fractal type network, which gives a much higher conductivity especially at low-volume fractions. For composites with a fractal type ATO network a second effect was found. Decreasing the amount of on ATO grafted MPS resulted in an increase of the electrical conduction between the ATO particles. 相似文献
409.
A.D. Linde 《Physics letters. [Part B]》1982,116(5):335-339
The behaviour of the scalar fied fluctuations in the exponentially expanding universe and their role in the new inflationary universe scenario are investigated. 相似文献
410.
V.V.?Temnov Email author K.?Sokolowski-Tinten P.?Zhou D.?von der Linde 《Applied Physics A: Materials Science & Processing》2004,78(4):483-489
We describe optical interferometry with 100 fs time resolution and a spatial resolution of approximately one micrometer. Using a pump-probe scheme and a 2D-Fourier transformation algorithm, we are able to retrieve from the interferograms very small changes in the phase and the amplitude of the reflected probe pulses. The performance of the technique is illustrated by measurements of transient and permanent surface modifications of crystalline GaAs after exposure to intense femtosecond laser pulses with fluences near the ablation threshold. PACS 78.47.+p; 42.65.Re; 42.15.Eq; 68.35.Ja 相似文献