全文获取类型
收费全文 | 119篇 |
免费 | 0篇 |
国内免费 | 1篇 |
专业分类
化学 | 69篇 |
晶体学 | 4篇 |
力学 | 2篇 |
数学 | 4篇 |
物理学 | 41篇 |
出版年
2022年 | 2篇 |
2021年 | 1篇 |
2019年 | 3篇 |
2018年 | 1篇 |
2016年 | 2篇 |
2013年 | 4篇 |
2012年 | 6篇 |
2011年 | 6篇 |
2010年 | 6篇 |
2009年 | 8篇 |
2008年 | 6篇 |
2007年 | 2篇 |
2006年 | 6篇 |
2005年 | 6篇 |
2004年 | 2篇 |
2003年 | 6篇 |
2002年 | 5篇 |
2001年 | 5篇 |
2000年 | 6篇 |
1996年 | 4篇 |
1994年 | 1篇 |
1993年 | 6篇 |
1992年 | 5篇 |
1991年 | 1篇 |
1986年 | 3篇 |
1985年 | 1篇 |
1983年 | 1篇 |
1980年 | 1篇 |
1979年 | 3篇 |
1978年 | 2篇 |
1977年 | 2篇 |
1976年 | 1篇 |
1974年 | 4篇 |
1972年 | 1篇 |
1938年 | 1篇 |
排序方式: 共有120条查询结果,搜索用时 31 毫秒
21.
Animesh Chakravorty 《Journal of Chemical Sciences》1994,106(6):1341-1348
Reactions involving the coupled transfer of electrons and protons are called electroprotic reactions. In this article we briefly
describe some of our experiences with electroprotic reaction as a tool for executing interesting chemical transformations. 相似文献
22.
23.
Zinc nanoparticles were grown within gel-derived silica films by applying a direct current voltage. Pattern formation of metallic Zn was studied as a function of applied voltage and metal-silica ratio. Average particle size varied from 5.2 to 20.2 nm by changing the applied voltage and silica concentration. It was found that the transition from fractal to dendritic morphology was possible due to crystalline anisotropy. From high-resolution transmission electron microscopy images and X-ray diffraction pattern a possible model is proposed to explain this observation. 相似文献
24.
The study compares the effect of incorporation of three different groups of anti-hyperlipidemic drugs, namely niacin, simvastatin, and fenofibrate on the phase profile of liposomal membranes of dipalmitoylphosphatidylcholine (DPPC). The fluorescence anisotropy studies, using 1,6-diphenyl-1,3,5-hexatriene as fluorescent probe, have shown that the lipophilic molecule fenofibrate changes phase behavior of DPPC liposomal membrane to a greater extent compared to the changes produced by amphiphilic simvastatin and hydrophilic niacin. This variation in effect can be attributed to the nature of the drug molecules and hence their location in different parts of the liposomal membrane. We have also calculated the changes in van’t Hoff enthalpy values in all these three cases and observed that these values decreased with increase in drug concentrations in the case of simvastatin but for fenofibrate and niacin the effect is completely the reverse. In order to get a better insight, the fraction of motionally restricted lipid molecules has been calculated. 相似文献
25.
Suman Bhandary Ruma Basu Smarajit Manna Sukhen Das Papiya Nandy 《Phase Transitions》2013,86(3):221-227
Membrane fusion is an important process in a wide range of cellular and sub-cellular activities. It is evident that during the intermediate stages of fusion some transitory non-bilayer configurations must appear within the lipid moiety. Using fluorescence techniques, we have studied here the process of aggregation and fusion of liposomes made of lipids, namely 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). When mixed together, the complete fusion between these two liposomes took around 44 h as both DPPC and DMPC favour lamellar configuration. When the mixture was incubated at 42°C the fusion process was completed after 23 h. But, when 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) was added in the liposomal matrix the time for fusion was reduced to 21 h for mixture without incubation and 17 h when the mixture was incubated. This indicates that DPPE having a tendency to assume non-lamellar conformation, promoted destabilisation of the lamellar conformation within the liposome which facilitated the fusion between two apposing bilayers. 相似文献
26.
Synthesis and thermal properties of a series of Schiff base oligomers derived from naturally occurring cholesterol are described. In particular, four of them show smectic A and/or chiral nematic phase/s or an unknown mesophase, while the other is non-mesomorphic. Molecular packing in the SmA phase has been determined by the HRXRD experiment. 相似文献
27.
Ghosh Bidisha Roy Shubham Bardhan Souravi Mondal Dhananjoy Saha Ishita Ghosh Saheli Basu Ruma Karmakar Parimal Das Kaustuv Das Sukhen 《Journal of fluorescence》2022,32(4):1489-1500
Journal of Fluorescence - This article reports the fluorometric detection of toxic hexavalent chromium Cr (VI)) in wastewater and Cr (VI) contaminated living cells using in-situ grown carbon... 相似文献
28.
29.
Debamitra Chakravorty Saravanan Parameswaran Vikash Kumar Dubey Sanjukta Patra 《Applied biochemistry and biotechnology》2012,167(3):439-461
Organic solvent-stable lipases have pronounced impact on industrial economy as they are involved in synthesis by esterification, interesterification, and transesterification. However, very few of such natural lipases have been isolated till date. A study of the recent past provided few pillars to rely on for this work. The three-dimensional structure, inclusive of the surface and active site, of 29 organic solvent-stable lipases was analyzed by subfamily classification and protein solvent molecular docking based on fast Fourier transform correlation approach. The observations revealed that organic solvent stability of lipases is their intrinsic property and unique with respect to each lipase. In this paper, factors like surface distribution of charged, hydrophobic, and neutral residues, interaction of solvents with catalytically immutable residues, and residues interacting with essential water molecules required for lipase activity, synergistically and by mutualism contribute to render a stable lipase organic solvent. The propensity of surface charge in relation to stability in organic solvents by establishing repulsive forces to exclude solvent molecules from interacting with the surface and prohibiting the same from gaining entry to the protein core, thus stabilizing the active conformation, is a new finding. It was also interesting to note that lipases having equivalent surface-exposed positive and negative residues were stable in a wide range of organic solvents, irrespective of their LogP values. 相似文献
30.
Arghya Chakravorty Emilio Gallicchio Emil Alexov 《Journal of computational chemistry》2019,40(12):1290-1304
A novel grid-based method is presented, which in conjunction with a smooth Gaussian-based model of atoms, is used to compute molecular volume (MV) and surface area (MSA). The MV and MSA are essential for computing nonpolar component of free energies. The objective of our grid-based approach is to identify solute atom pairs that share overlapping volumes in space. Once completed, this information is used to construct a rooted tree using depth-first method to yield the final volume and SA by using the formulations of the Gaussian model described by Grant and Pickup (J. Phys Chem, 1995, 99 , 3503). The method is designed to function uninterruptedly with the grid-based finite-difference method implemented in Delphi, a popular and open-source package used for solving the Poisson–Boltzmann equation (PBE). We demonstrate the time efficacy of the method while also validating its performance in terms of the effect of grid-resolution, positioning of the solute within the grid-map and accuracy in identification of overlapping atom pairs. We also explore and discuss different aspects of the Gaussian model with key emphasis on its physical meaningfulness. This development and its future release with the Delphi package are intended to provide a physically meaningful, fast, robust and comprehensive tool for MM/PBSA based free energy calculations. © 2019 Wiley Periodicals, Inc. 相似文献