新型正极材料三硫代环磷氮烯无机聚合物的合成

采用缩合聚合方法合成了新型三硫代环磷氮烯无机聚合物[(NPS₃)₃]_n，利用红外光谱测试与元素含量分析技术证明了[(NPS₃)₃]_n的分子结构与组成，并对聚合物材料的粒度、比表面积及微观形貌进行了考察。TG/DTA 实验证明材料在200 ℃ 以下具有良好的热稳定性。循环伏安测试表明[(NPS₃)₃]_n正极材料在锂电池体系具有2.15 V的电化学还原电位和2.45 V的电化学氧化电位，经充放电循环实验观察，材料的首次放电容量达到749.0 mAh·g^-1，与理论容量(759.0 mAh·g^-1)十分接近；经过50次充放电循环后，放电容量保持在674.8 mAh·g^-1，具有很高的使用容量和优秀的循环性能。     

Harnessing Quinone Methides: Total Synthesis of (±)‐Vaticanol A

Although quinone methides are often postulated as intermediates in the biosynthesis of many polyphenolic natural products, deploying their power in a laboratory setting to achieve similar bond constructions has sometimes proven challenging. Herein, a total synthesis of the resveratrol trimer vaticanol A has been achieved through three instances of quinone methide chemistry. These operations, one of which succeeded only under very specific conditions, expediently generated its [7,5]‐carbocyclic core, afforded a unique sequence for dihydrobenzofuran formation, and concurrently generated, in addition to the target molecule, a series of diastereomers reflective of many other isolates.     

Traceless solid-phase synthesis of hydroxylated cyclopentenones

Intramolecular nitrone-alkene cycloadditions on solid phase can be performed using polymer-bound hydroxylamine. Condensation of this reagent with sugar derived 4-pentenals followed by N-O cleavage, quaternization of the amine thus produced, and finally oxidative elimination of the amino group detaches the chiral hydroxylated cyclopentenones from the polymer. The natural antibiotic pentenomycin I was prepared in this way.     

Effect of Caffeic acid on the Tumor Cells U937 Evaluated by an Electrochemical Voltammetric Method

Catl'eicacidisoneofthemajorpolyphenolcompoundsfoundinnumerousplantspecies.t'llbicbcallbeaccumulatedto29/Oinhumandailydieti.Itiswidelyrecognizedtobedlllioxidallt.whichcallscavengereactivespeciesofoxygenandnitrogen?.itsantimutagenecit}hasalsobeenevaluatedbySa/l}]()}7el/atjphi)]lllrllll)Isystem'.however.thereisnorepoltofthischemical'sdirecteft'ectontumorcells.Recently,asakindofnon-morpllologicalobservationmethod,electrochemicalmethodhasbeendevelopedforfollowingcellhealthstates#andevaluatingeffec…     

时间分辨荧光免疫分析法间接测定雌二醇

以氯磺酰基噻吩甲酰三氟丙酮（CTTA）为铕（Eu)的螯合剂,羊抗鼠（SAM）的IgG为二抗,用SAM－IgG-CTTA-Eu作标记二抗,建立了以竞争抑制为基础的时间分辨荧光免疫分析测定离雌二醇（E2）的新方法。同均相方法相比灵敏度有很大提高,测定雌二醇（E2）的线性范围为2．5－200pg/mL,检测限为2.5pg/mL。这一方法可望用于E2的临床检测。     

GABAA受体萜类抑制剂构效关系研究

采用DISCOtech方法建立了大鼠和家蝇GABAA受体萜类抑制剂的药效团模型, 根据药效团模型叠加规则建立了大鼠和家蝇GABAA受体萜类抑制剂CoMFA模型, 模型的交叉验证相关系数分别为0.713和0.738. 构效关系研究显示， 家蝇和大鼠受体抑制剂结合部位之间存在一个主要差别: 与受体作用的抑制剂的负电荷基团取代有利于保持其对哺乳动物的高抑制活性, 而保持对昆虫的高抑制活性是不需要的, 从而为寻找先导化合物和设计高选择性杀虫剂提供了理论指导.     

Synthesis of ent-gabosine E from d-mannose by intramolecular nitrone–olefin cycloaddition

Intramolecular nitrone–olefin cycloaddition in a mannose template followed by N–O cleavage, quaternization of the resulting amine, and finally oxidative elimination of the amino group affords, after deprotection, ent-gabosine E in enantiomerically pure form.     

Liposome Immunoassay for Determination of Phenytoin

Inthispaper,arapid,sensitive,andsimpleliposomeimmunoassay(LIA)lbrdetectingphenytoinhasbeenestablished.Phenytoinisuscdtocurecpilepsy,butinclinicalpractice,theefficientconcentrationofphenytoininpatient'sseraisverynarrow,about1O~2Opg/ml.Iftheconcentrationofphenytoininserumislessthantheefficientconcentration,thereisnoeffectofmedicine.Butiftheconcentrationrangewerc2O~4Ollg/ml,themedicinecouldbringsideeffect.Ifthcconcentrationbecomesgreater,thenitcancausepoisoning.Becausetherearemanyfactorswhich…     

An improved approach to chiral cyclopentenone building blocks. Total synthesis of pentenomycin I and neplanocin A

An improved approach to enantiomerically pure hydroxylated cyclopentenones is reported here, which involves intramolecular nitrone cycloaddition of sugar-derived chiral pent-4-enals and hex-5-en-ones-2 followed by N-O bond cleavage, quaternization of the amine thus produced, and finally oxidative elimination of the amino group. Synthesis of pentenomycin I and neplanocin A is described following this methodology.     

一个除数为2m(2n±1)的快速除法

本文提出了一个除数为常数2^m(2ⁿ±1)形式的除法的快速算法。该算法可非常简单的直接由硬件和软件实现。AP-601高速向量计算机无冲突访问存贮系统的素数模地址变换的硬件实现,便是该算法的成功应用。文中不仅给出了算法的数学基础,也给出了某些性能指标。