Analysis of stop consonant production errors in developmentally dysphasic children

The speech production skills of 12 dysphasic children and of 12 normal children were compared. The dysphasic children were found to have significantly greater difficulty than the normal children in producing stop consonants. In addition, it was found that seven of the dysphasic children, who had difficulty in perceiving initial stop consonants, had greater difficulty in producing stop consonants than the remaining five dysphasic children who showed no such perceptual difficulty. A detailed phonetic analysis indicated that the dysphasic children seldom omitted stops or substituted nonstop for stop consonants. Instead, their errors were predominantly of voicing or place of articulation. Acoustic analyses suggested that the voicing errors were related to lack of precise control over the timing of speech events, specifically, voice onset time for initial stops and vowel duration preceding final stops. The number of voicing errors on final stops, however, was greater than expected on the basis of lack of differentiation of vowel duration alone. They appeared also to be related to a tendency in the dysphasic children to produce final stops with exaggerated aspiration. The possible relationship of poor timing control in speech production in these children and auditory temporal processing deficits in speech perception is discussed.     

Epoxidation of olefins by hydrogen peroxide in the presence of tetrachloroacetone

1,1,3,3-Tetrachloroacetone, an inexpensive, commercially available material, has been shown to be effective in mediating the hydrogen peroxide oxidation of a variety of olefins to epoxides. The chloroacetone is readily recovered for re-use.     

Untersuchung der Atmung einzelner Gewebekulturen mit Radiokohlenstoff

Zusammenfassung In Embryonalextrakt gehaltenen Kulturen von Hühnchenfibroblasten wurde radioaktive Glukose zugeführt und die Aktivität des erzeugten Kohlendioxyds bestimmt. Aus dieser Aktivität wurde auf die veratmete Glukosemenge geschlossen. Deckglaskulturen veratmeten bei Zufuhr von 6 oder mehr Glukose 1 . Nach einigen Stunden wurde ein Maximum der Atmung erreicht, nach wenigen Tagen kam die Atmung praktisch zum Stillstand. Auch Embryonalextrakt allein (ohne Kultur) entwickelt eine geringe Menge Radiokohlendioxyd.Roller-Kulturen veratmen viel mehr (unter Umständen hundertemal mehr) Glukose als Deckglaskulturen; auch in diesem Falle ist die Kohlendioxydentwicklung der Kultur viel größer als die des Nährmediums. Deckglas- undRoller-Kulturen veratmen Glukose auch in isotoner Salzlösung ohne Zusatz von Embryonalextrakt.     

Ultrasonic cleavage of thioethers

The rates of DPPH (diphenylpicrylhydrazyl) trapping and the sonolytical products obtained during the sonolysis of thioethers at normal and low temperature are reported. CS2, lower sulfides, thiophene, and sulfurized species are the common products during the ultrasonic irradiations. Hydrocarbons are also obtained during the sonolysis of diallyl sulfide, diethyl disulfide, and dipropyl disulfide. Furthermore, aldehydes are obtained as oxidized species; SO2 is found at 208 K. The principal sonochemical process appears to be the cleavage of C-S or S-S bond with secondary combinations and rearrangements. DPPH has been used to probe the sonolytical potential of thioethers. The results show a good correlation between the rates of DPPH trapping and the vapor pressures of thioethers. In conclusion, a lower vapor pressure results in a higher sonolytical rate. The sonochemical behaviors of thioethers have strong qualitative similarities to the pyrolysis.     

Correlation of the elastic characteristics of Arimid PM with the elasticity modulus of its crystal lattice

Studies were made of the elastic characteristics (longitudinal elasticity modulus, elastic recovery) of Arimid PM fibers and of the longitudinal elasticity modulus of the crystal lattice of these samples. The elasticity modulus of the crystallites was determined by x-ray diffraction studies of loaded fibers. It is shown that the studied samples practically instanteneously recover their starting length after removing the load; the sample and its crystal lattice have comparatively low elasticity moduli with nearly identical values. Based on this data, reasons are discussed for the high elastic recovery of Arimid fibers and for the low elasticity modulus of its crystal lattice.Leningrad Branch, All-Union Scientific-Research Institute of Synthetic Fibers. Translated from Mekhanika Polimerov, No. 5, pp. 771–773, September–October, 1972.     

On the quasi-chemical theory of solutions

The classical canonical partition function for a one-dimensional, two-component system is examined for the case of nearest-neighbor interactions. The quasi-chemical model of solid solutions is found to be a natural consequence of the definition of the partition function when one replaces the normal configurational energy with a configurational free energy. Consequently, the quasi-chemical theory may be viewed as a consequence of the definition of the partition function and not as merely a physically pleasing model.     

THE NATURE OF ULTRAVIOLET LIGHT-INDUCED STRAND BREAKAGE IN DNA CONTAINING BROMOURACIL

Abstract— Single-strand breaks are produced in the phosphodiester backbone of ultraviolet-light-irradiated 5–bromodeoxyuridine-containing DNA (BU-DNA) after treatment with alkali. No radiation dependent breakage is observed in thymine-containing DNA (thy-DNA). The relative yields of breaks terminated by 5'-hydroxyl and 5'-phosphate groups was determined by measuring the rate of phosphorylation achieved with polynucleotide kinase in BU-DNA single strands before and after treatment with alkaline phosphatase. The ratio of 5'-phosphate to 5' hydroxyl groups ranged from 2.3 to 2.9 in different experiments. When cysteamine was present during irradiation no new end groups were produced.
In order to identify the nucleoside(s) at the 5'-termini, phosphate groups were removed with alkaline phosphatase and the 5'-hydroxyl groups were phosphorylated with polynucleotide kinase. Electrophoresis of enzymatic digests showed a single ³²P-labeled component migrating more rapidly than any of the four usual 5'-mononucleotides. Upon column chromatography this component resolved into a major peak coincident with 5'-dUMP and a lesser unidentified constituent. No 5'-dBUM³²P was observed among these nucleotides.