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排序方式: 共有473条查询结果,搜索用时 78 毫秒
31.
Soumitra Hazra Maidul Hossain Gopinatha Suresh Kumar 《Journal of inclusion phenomena and macrocyclic chemistry》2014,78(1-4):311-323
The complexation of three isoquinoline alkaloids berberine, palmatine and coralyne with α-, β-, and γ-CDs were studied by absorption, fluorescence, circular dichroism, NMR spectroscopy and microcalorimetric assay techniques. Their binding constant (K BH) values were determined by Benesi–Hildebrand equation. All the alkaloids formed 1:1 stoichiometry complexes with the cyclodextrins (CDs). The binding affinity is largest in β-CD followed by γ-, and α-CD for coralyne, followed by berberine and then palmatine. The thermodynamic parameters of the complexation were determined by calorimetry. The stoichiometry of complex formation and the variation of the apparent binding constant from spectroscopic studies were confirmed by calorimetry. The formation of the inclusion complexes was entropy driven in almost all the systems. Coralyne formed the strongest complex with all the CDs, followed by berberine and palmatine in that order. Coralyne-β-CD complex was studied through NMR, indicating more than one interaction mode. 相似文献
32.
Endophytes, being the co-evolution partners of green host plants, are factories of pharmaceutically valuable novel natural products. Cochliobolus sp. APS1, an endophyte of Andrographis paniculata (Green Chiretta), produces a plethora of natural bioactive compounds and the multipotent alkaloid Aziridine, 1-(2-aminoethyl)-, is the prime one among them. The isolate exhibited antibacterial, anti-biofilm, and antilarval potency. The MIC and MBC values of the ethyl-acetate culture extract ranged from 15.62 to 250 µg/mL against ten pathogenic microorganisms (including MRSA and VRSA). Killing kinetics data along with the leakage of macromolecules into the extracellular environment supports the cidal activity of the antibacterial principles. The broad spectrum antibacterial activity of Aziridine, 1-(2-aminoethyl)-, was optimized by a one-variable-at-a-time system coupled with response surface methodology, which led to a 45% enhancement of the antibacterial activity. The maximum response (22.81 ± 0.16 mm of zone of inhibition against MRSA) was marked in 250 mL Erlenmeyer flask containing 90 mL potato dextrose broth supplemented with (g%/L) glucose, 9.7; urea concentration, 0.74; with medium pH 6.48; after 8.76 days of incubation at 26 °C. APS1 strongly inhibited biofilm formation in the tested pathogenic microorganisms and acts as a larvicidal agent against the Dengue-vector Aedes aegypti. This is probably the first report of Aziridine, 1-(2-aminoethyl)-, from any endophytic source. Cochliobolus sp. APS1 possesses industrial importance for the production of bioactive alkaloids. 相似文献
33.
We consider a generalised two brane Randall–Sundrum model with non-zero cosmological constant on the visible TeV brane. Massive Kaluza–Klein modes for various bulk fields namely graviton, gauge field and antisymmetric second rank Kalb–Ramond field in a such generalized Randall–Sundrum scenario are determined. The masses for the Kaluza–Klein excitations of different bulk fields are found to depend on the brane cosmological constant indicating interesting consequences in warped brane particle phenomenology. 相似文献
34.
Dipak Maity S.N. Kale Jun-Min Xue 《Journal of magnetism and magnetic materials》2009,321(19):3093-3098
In this paper, water-soluble magnetite nanoparticles have been directly synthesized by thermal decomposition of iron (III) acetylacetonate, Fe(acac)3 in tri(ethyleneglycol). Size and morphology of the nanoparticles are determined by transmission electron microscopy (TEM) and dynamic light scattering (DLS) measurements while the crystal structure is identified using X-ray diffraction (XRD). Surface charge and surface coating of the nanoparticles are recognized using Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectra (XPS) and zeta potential measurements. Magnetic properties are determined using vibrating sample magnetometer (VSM) and superconducting quantum interference device (SQUID) measurements. The results show that as-prepared magnetite nanoparticles are relatively monodisperse, single crystalline and superparamagnetic in nature with the blocking temperature at around 100 K. The magnetite nanoparticles are found to be highly soluble in water due to steric and electrostatic interactions between the particles arising by the surface adsorbed tri(ethyleneglycol) molecules and associated positive charges, respectively. Cytotoxicity studies on human cervical (SiHa), mouse melanoma (B16F10) and mouse primary fibroblast cells demonstrate that up to a dose of 80 μg/ml, the magnetic nanoparticles are nontoxic to the cells. Specific absorption rate (SAR) value has been calculated to be 885 and 539 W/gm for samples with the iron concentration of 1 and 0.5 mg/ml, respectively. The high SAR value upon exposure to 20 MHz radiofrequency signifies the applicability of as-prepared magnetite nanoparticles for a feasible magnetic hyperthermia treatment. 相似文献
35.
Hydroxyl compounds readily add to dihydropyran in presence of a catalytic amount of ceric ammonium nitrate to give high yield of tetrahydropyranyl ethers. 相似文献
36.
To exploit the parallelism of optics in data processing,a suitable number system and an efficient encoding/decoding scheme for handling the data are very essential.In the field of optical computing and parallel information processing,several number systems like binary,quaternary,octal,hexadecimal,etc.have been used for different arithmetic and algebraic operations.Here,we have proposed an all-optical conversion scheme from its binary to its other 2n radix based form with the help of terahertz optical asymmetric demultiplexer (TOAD) based tree-net architecture. 相似文献
37.
The indium-mediated allylation of chiral hydrazones was investigated. Essentially complete diastereoselectivity and quantitative yields were obtained for substrates derived from both aromatic and aliphatic aldehydes. [reaction--see text] 相似文献
38.
A parametric study on fluid-structure interaction problems 总被引:1,自引:0,他引:1
This paper deals with finite element analysis of the fluid-structure systems considering the coupled effect of elastic structure and fluid. The equations of motion of the fluid considered inviscid and compressible are expressed in terms of the pressure variable alone. The elastic structure and the fluid domain are treated as two separate systems and discretized with finite elements. The solution of the coupled system is accomplished by solving the two systems separately with the interaction effects at the fluid-solid interface enforced by a developed iterative scheme. Non-divergent pressure and displacement are obtained simultaneously through a few numbers of iterations. Studies show the accuracy of the proposed algorithm, while comparing with the existing ones available in the literature. The parametric study of the coupled system shows the importance of fluid height and material property of the structure. 相似文献
39.
In this present investigation, we describe the steady state current voltage (I–V) characteristic of Crystal violet dye dispersed
solid state photoelectrochemical cell (PEC). Typical behavior of dark current-voltage characteristic by increasing and decreasing
external bias voltage has a similar form like hysterisis in nature. Although we have already observed this hysterisis nature
in case of both forward and reverse bias condition, yet it is clear that the reverse hysterisis curve is more prominent than
forward hysterisis. In this paper, we are getting double values of current (I) for a single value voltage, which is also helpful
to understand the charge transport process through disordered materials. As the bias increases, the distribution of traps
depth, which is exponential in nature, changes toward order state (resulting increase in disordered parameter α) This means
that as α increases, it tends to reach the most order state of material. When external bias voltage is at 3.5 V, the value
of disorder parameter becomes 1, and when bias voltage is beyond 3.5 V, the diffusion comes enhanced in nature. 相似文献
40.
Rupankar PairaArindam Maity Shyamal MondalSubhendu Naskar Krishnendu B. SahuPritam Saha Abhijit HazraE. Padmanaban Sukdeb BanerjeeNirup B. Mondal 《Tetrahedron letters》2011,52(14):1653-1657
Basic alumina supported solvent-free one-pot synthesis of pyridine-fused polycyclic diazepaniums was achieved under microwave irradiation. The process was successfully extended to the synthesis of pyridine-fused bicyclic imidazolidiniums and tetrahydro-pyrimidiniums and also of tri- and tetracyclic diaza-heterocycle-fused quinoliniums. The dual characteristic of basic alumina, a solid support as well as a base, was successfully employed in the current investigation. The method emerged to be an effective route in terms of product yield, reaction time, and ease of purification and most importantly for environment friendly protocols. 相似文献