Some characteristics of high multiplicity (≧45) proton-AgBr interactions at 800 GeV

Experimental results on some characteristics of high multiplicity (≧45) proton-AgBr interactions at 800 GeV are presented. The results are compared with those in lower multiplicity regions as well as for CNO target. The various parameters investigated here are pseudorapidity distribution, mean normalised multiplicity, mean number of intranuclear collisions and normalised pseudorapidity.     

Chiral Lagrangian and skyrmion from quark and parity-doublet determinants

We consider the effective action of the chiral quark model to leading order in the number of colors. A set of massive ghost-like Gervais-Lee fermion doublets is introduced which effectively simulate an asymptotically free behavior for the quarks at short distances. This suppresses the vacuum instability and leaves the Wess-Zumino sector unspoiled. At small momenta, we show that the action generated in this way compares well with experiment by performing a chiral expansion up to fourth order. It is found that this action supports stable soliton solutions with baryon number one. Masses, mass-splittings and the sigma-term are estimated in theSU(2) limit.Unité de Recherche des Universités Paris 11 et Paris 6 associée au CNRS     

Certain fractional derivative formulae involving the product of a general class of polynomials and the multivariableH-function

In the present paper, we obtain three unified fractional derivative formulae (FDF). The first involves the product of a general class of polynomials and the multivariableH-function. The second involves the product of a general class of polynomials and two multivariableH-functions and has been obtained with the help of the generalized Leibniz rule for fractional derivatives. The last FDF also involves the product of a general class of polynomials and the multivariableH-function but it is obtained by the application of the first FDF twice and it involves two independent variables instead of one. The polynomials and the functions involved in all our fractional derivative formulae as well as their arguments which are of the typex ^ρ Π _i=1 ^s (x ^t _i +α _i ) ^σ _i are quite general in nature. These formulae, besides being of very general character have been put in a compact form avoiding the occurrence of infinite series and thus making them useful in applications. Our findings provide interesting unifications and extensions of a number of (new and known) results. For the sake of illustration, we give here exact references to the results (in essence) of five research papers [2, 3,10, 12, 13] that follow as particular cases of our findings. In the end, we record a new fractional derivative formula involving the product of the Hermite polynomials, the Laguerre polynomials and the product ofr different Whittaker functions as a simple special case of our first formula.     

High pressure raman scattering in Pb5Ge3O11

The pressure dependence of various phonon modes has been investigated through the ferro-paraelectric phase transition. Most mode frequencies harden before levelling off above the phase transition. Mode Grüneisen parameters are estimated from the pressure dependence of phonon frequencies.     

Easy To Synthesize,Robust Organo‐osmium Asymmetric Transfer Hydrogenation Catalysts

Asymmetric transfer hydrogenation (ATH) is an important process in organic synthesis for which the Noyori‐type Ru^II catalysts [(arene)Ru(Tsdiamine)] are now well established and widely used. We now demonstrate for the first time the catalytic activity of the osmium analogues. X‐ray crystal structures of the 16‐electron Os^II catalysts are almost identical to those of Ru^II. Intriguingly the precursor complex was isolated as a dichlorido complex with a monodentate amine ligand. The Os^II catalysts are readily synthesised (within 1 h) and exhibit excellent enantioselectivity in ATH reactions of ketones.     

The importance of the N-H bond in Ru/TsDPEN complexes for asymmetric transfer hydrogenation of ketones and imines

Ru(II) complexes of TsDPEN containing two alkyl groups on the non-tosylated nitrogen atom are poor catalysts for asymmetric transfer hydrogenation of ketones and imines; this observation provides direct evidence for the importance of the N-H interaction in the transition state for ketone reduction.     

Development of a novel reporter gene vector for cell based angiogenic studies

Angiogenesis is a promising area of research that targets key therapeutic areas like cancer; wound healing, inflammatory diseases, etc. There is an increasing demand for screening of potential angiogenic and anti-angiogenic agents using sensitive, robust cell-based assays. We have developed a reporter vector containing cis-acting elements that respond to growth factors/angiogenic ligands for use in a cell-based luciferase reporter assay. We performed transient transfection of our reporter gene vector in MCF-7 cells to establish its application for screening of potential pro/anti-angiogenic agents. Reporter gene transactivation studies with different concentrations of fetal bovine serum clearly indicated that the vector is functionally responsive to the angiogenic signals mediated by serum growth factors. We also used endostatin to inhibit transactivation and prove responsiveness to the anti-angiogenic agent. This vector is a promising tool for studying angiogenesis using cell-based reporter gene assays.     

Chiral discrimination in biomimetic systems: Phenylalanine

Chiral discrimination and recognition is important in peptide biosynthesis, amino acid synthesis and drug designing. Detailed structural information is available about the peptide synthesis in ribosome. However, no detailed study is available about the discrimination in peptide synthesis. We study the conformational energy variation of neutral methoxy phenyl alanine molecule as a function of its different dihedral angle to locate the minimum energy conformation using quantum chemical theory. We compared the intermolecular energy surfaces of phenyl alanine molecule in its neutral and zwitterionic state using quantum chemical theory as a function of distance and mutual orientation. The energy surfaces are studied with rigid geometry by varying the distance and orientation. The potential energy surfaces of L-L and D-L pairs are found to be dissimilar and reflect the underlying chirality of the homochiral pair and racemic nature of the heterochiral pair. The intermolecular energy surface of homochiral pair is more favourable than the corresponding energy surface of heterochiral pair.