Improved electrochemical performance of supercapacitors by utilizing ternary Pd-AC-doped NiO nanostructure as an electrode material

Journal of Solid State Electrochemistry - Recent applications of supercapacitors in modern society are limited due to their poor electrochemical properties like energy density and cyclic stability,...     

Comparative larvicidal activity of different species of Ocimum against Culex quinquefasciatus

Ocimum is a genus of aromatic herbs, undershurbs or shrubs distributed in the tropical and warm temperate regions of the world. Larvicidal activity of essential oils and different extracts of O. sanctum, O. basilicum and O. gratissimum were compared on laboratory reared and field collected larvae of Culex quinquefasciatus. Thin layer chromatographic analysis revealed that all the three species have similar components and results showed the presence of steroids and triterpenoids. The larvicidal activity was determined in terms of LD?? value on late third or early fourth instar larvae for a period of 24?h. A comparison of LD?? value has shown that O. basilicum is more active than the other two species. The LD?? value of O. basilicum and O. sanctum oil were 39.31 and 40.02 on laboratory reared larvae and 129.53 and 139.49 on field collected larvae. Laboratory reared larvae were more sensitive than field collected larvae.     

XRD,magnetic and Mössbauer spectral studies of nano size aluminum substituted cobalt ferrites (CoAlxFe2−xO4)

Aluminum substituted cobalt ferrites having particle size ∼10 nm were prepared using aerosol route, which increases with annealing temperature. The unit cell parameter ‘a’ and saturation magnetization decreases linearly with the increase of aluminum concentration. This is due to the smaller ionic radius and the diamagnetic nature of the Al³⁺, respectively. Room temperature Mössbauer spectra of the samples annealed at 1200 °C show broad sextets, which were fitted with different sextets, indicating different local environment of both tetrahedrally and octahedrally coordinated iron cation. Further, hyperfine field of the samples decreases with the increase of Al³⁺ concentration due to the fact that the Al³⁺ diamagnetic species reduce the magnetic interactions. Cations distribution indicated a increase in Fe³⁺(oct.)/Fe³⁺(tet.) ratio on increasing the Al³⁺ concentration.     

Mössbauer spectroscopic studies of spin crossover in tris(N, N′-dialkyldithiocarbamato) iron (III) complexes: effect of alkyl substituents

Spin crossover behavior in tris(N,N′-dialkyldithiocarbamato) iron(III) complexes with varying alkyl groups has been studied by variable temperature magnetic moment and Mössbauer spectral studies. All the complexes may be divided into three broad groups; high spin (μ _eff > 4.8 BM), intermediate spin (μ _eff?=?3.5???4.6 BM) and low spin (μ _eff?< 3.2 B.M). Room temperature (RT) Mössbauer spectra exhibit an asymmetric doublet resolved into two doublets corresponding to high and low spin states. Estimated % contributions of HS and LS states and calculated μ _eff were comparable with the experimentally determined values. It has been shown that some complexes undergo spin crossover, ⁶A₁g→²T₂g whereas others exhibit spin transitions ⁶A₁g →⁴T₁g or ⁴T₁g → ²T₂g. IR spectra show characteristic ν _(Fe???S) bands in the region 208–285 (HS) and 311–380 cm^???1 (LS). Nature of alkyl groups affects the spin state.     

A study of pyrazolo-benzimidazole derivatives as spleen tyrosine kinase inhibitors: an in-silico approach

Structural Chemistry - In an effort to contribute designing of improved anticancer molecules, in-silico prediction data including pharmacophore hypothesis, 3D-QSAR model, and molecular docking...     

Estimation of various scattering parameters and 2-DEG mobilities from electron mobility calculations in the three conduction bands Γ, L and X of gallium arsenide

The electron drift mobility in Γ conduction band of GaAs has been calculated before, but for the first time, we have made attempts to estimate the electron mobilities in higher energy L and X minima. We have also calculated the value of mobility of two-dimensional electron gas needed to predict hetero-structure device characteristics using GaAs. Best scattering parameters have been derived by close comparison between experimental and theoretical mobilities. Room temperature electron mobilities in Γ, L and X valleys are found to be nearly 9094, 945 and 247 cm²/V-s respectively. For the above valleys, the electron masses, deformation potentials and polar phonon temperatures have been determined to be (0.067, 0.22, 0.39m ₀), (8.5, 9.5, 6.5 eV), and (416, 382, 542 K) as best values, respectively. The 2-DEG electron mobility in Γ minimum increases to 1.54 × 10⁶ from 1.59 × 10⁵ cm²/V-s (for impurity concentration of 10¹⁴ cm⁻³) at 10 K. Similarly, the 2-DEG electron mobility values in L and X minima are estimated to be 2.28 × 10⁵ and 1.44 × 10⁵ cm²/V-s at 10 K, which are about ∼4.5 and ∼3.9 times higher than normal value with impurity scattering present.      

Quantitative analysis of 5 alpha-reductase inhibitors in DU145 cells using matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry and high-performance liquid chromatography/tandem mass spectrometry

N-(Dicyclohexyl)acetylpiperidine-4-benzylidene-4-carboxylic acid (1) is an excellent in vitro inhibitor of 5 alpha-reductase (5 alpha R). Compound 1 showed, however, much lower inhibition activity of 5 alpha R in vivo than in vitro, which might be caused by poor membrane permeability. The methyl ester of 1 (1a) was therefore tested as a model prodrug to see if it has better permeability properties than the corresponding acid 1. It was also monitored that this methyl ester was cleaved into the active compound 1 within the DU145 cells. Quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) and high-performance liquid chromatography/tandem mass spectrometry (HPLC/MS/MS) methods were established with reliable linearity factors (0.996 for MALDI-TOFMS and 0.998 for HPLC/MS/MS) and reproducibility (relative standard deviation = 6.5% for MALDI-TOFMS and 2.8% for HPLC/MS/MS). The samples for MS analysis were effectively prepared from the cell homogenates using solid-phase extraction, with a high recovery of 90% on average. The intracellular amount of 1a (1.7 nmol) was much higher than that of 1 (0.032 nmol) in DU145 cells after 6 h of incubation. After incubation with the ester (1a), the cleaved acid (1) was detected within the cells. The concentration of acid 1 (0.045 nmol) in this experiment was higher than the acid content (0.032 nmol) after direct incubation with 1. Surprisingly, high amounts of the cleaved compound 1 were found outside the cells after 6 h of incubation with 1a.     

Matrix-assisted laser desorption/ionization on-target method for the investigation of oligosaccharides and glycosylation sites in glycopeptides and glycoproteins

The significance of glycoproteins in living systems instigates the ceaseless expansion of new techniques and procedures for the analysis of biological samples. Many of these applications are focused on improving the detection limit of analyzed material. In a previous study, we described a procedure for the detection of oligosaccharides cleaved from tryptic glycopeptides. Treatment of deglycosylated fractions with phenylhydrazine gave rise to peaks consistent with labeled glycans, and both types of compounds--deglycosylated peptides and oligosaccharides--were recorded from one spot and observed in one matrix-assisted laser desorption/ionization (MALDI) mass spectrum for the first time. Here, we added an additional step to this simple procedure of deglycosylating glycopeptides directly from the target spot of the first analyzed glycosylated peptides. For the purpose of this new study, a mixture of 2-aza-2-thiothymine and phenylhydrazine hydrochloride showed to be an excellent matrix for glycopeptides, oligosaccharides, deglycosylated peptides and moreover it allowed PNGaseF to be active enough to cleave oligosaccharides from peptides. The efficiency of this procedure is demonstrated on a series of intact glycoproteins and on the analysis of tryptic peptides obtained from IgG and total mouse serum. This one-step on-target deglycosylation method with subsequent derivatization on the same spot makes MALDI-MS analyses of glycopeptides fast, simple and accessible for biological samples, where classical procedures cannot produce useful results.     

Integral transform and fractional derivative formulas involving the extended generalized hypergeometric functions and probability distributions

In the present paper, our aim is to establish several formulas involving integral transforms, fractional derivatives, and a certain family of extended generalized hypergeometric functions. As corollaries and consequences, many interesting results are shown to follow from our main results. A probability density function involving the extended generalized hypergeometric function is introduced, and its properties are studied. The corresponding properties of some of the classical probability distributions and their associated probability density functions are easily derivable as special cases of our general results. Copyright © 2016 John Wiley & Sons, Ltd.     

Magnesium ferrichromate nanoparticles: an efficient and recyclable catalyst in the synthesis of pyrano[2,3-c]pyrazole derivatives

Research on Chemical Intermediates - Magnetically separable magnesium ferrichromate nanoparticles (MgFeCrO4 NPs) were synthesized by aqueous combustion synthesis (ACS) using glycine as the fuel....