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排序方式: 共有140条查询结果,搜索用时 31 毫秒
11.
Seyed Mojtaba Amininasab Soheila Esmaili Mehdi Taghavi Zahed Shami 《International Journal of Polymer Analysis and Characterization》2016,21(8):686-696
A series of novel organosoluble polyamides (PAs) bearing different functional groups such as flexible ether, substituted imidazole, and xanthene rings and electron-withdrawing CF3 groups were synthesized from diamines and various dicarboxylic acids. The structures of diamines and PAs were fully characterized by elemental analysis, Fourier transform infrared spectroscopy, and proton nuclear magnetic resonance spectroscopy. The PAs showed good solubility in aprotic and polar organic solvents, with high thermal stability exhibiting the glass transition temperatures (Tgs) and 10% weight loss temperatures (T10%) in the range of 184–277°C and 410–480°C in N2 atmosphere, respectively. These polymers showed fluorescence emission upon irradiation with UV light. Diamine compounds and two of synthesized polymers were also screened for antibacterial activity against gram-positive and gram-negative bacteria, and the obtained results for all four combinations showed good inhibition. Extraction capability for heavy metal ions such as Cr3+, Pb2+, Hg2+, Cd2+, and Co2+ from aqueous solutions was also tested at 25°C and pH 7–8. 相似文献
12.
Nahid Shahabadi Soheila Kashanian Marzieh Khosravi Maryam Mahdavi 《Transition Metal Chemistry》2010,35(6):699-705
The water-soluble Ni(II) complex, [Ni(bipy)2(phen-dione)](OAc)2·2H2O (bipy = 2,2′-bipyridine and phen-dione = 1,10-phenanthroline-5,6-dione) has been synthesized and characterized by physico-chemical
and spectroscopic methods. The binding interactions of this complex with calf thymus DNA (CT-DNA) were investigated using
fluorimetry, spectrophotometry, circular dichroism and viscosimetry. In fluorimetric studies, the enthalpy and entropy of
the reaction between the complex and CT-DNA showed that the reaction is exothermic (ΔH = −123.9 kJ mol−1; ΔS = −323.5 J mol−1 K−1). The competitive binding studies showed that the complex could not release methylene blue completely. The complex showed
absorption hyperchromism in its UV–Vis spectrum with DNA. The calculated binding constant, K
b obtained from UV–Vis absorption studies was 2 × 105 M−1. Moreover, the complex induced detectable changes in the CD spectrum of CT-DNA, as well as changes in its viscosity. The
results suggest that this nickel(II) complex interact with CT-DNA via a groove-binding mode. 相似文献
13.
The objective of this study is to investigate the possibility of using Co-CNTs as a green reaction medium and a catalyst for the cyclo-condensation of o-aminobenzamide with various aldehydes. This inexpensive, non-toxic, and readily available catalyst efficiently catalyzes the above condensation for the synthesis of 2-aryl-2,3-dihydroquinazolin-4(1H)-ones. Compared to the classical reaction, this is a simple, highly yielding, time saving, and environmentally friendly method. 相似文献
14.
Javad?SafariEmail author Soheila?Gandomi-Ravandi 《Journal of the Iranian Chemical Society》2015,12(1):147-154
A supported carbon material is shown to be a highly efficient, eco-friendly and recyclable solid acid catalyst for the Biginelli reaction of aldehyde, β-ketoester and urea or thiourea under microwave irradiation in the absence of solvent. This method offers significant advantages such as efficiency, the excellent yield, avoidance of the organic solvents, mild reaction conditions, easy separation and simple operation. In addition, because of employing microwave as heating source and reducing use of organic solvents, this novel method emerges as a green-approach leading to less harmful residues. Furthermore, a mechanism was proposed to rationalize the reaction and the role of NiO–MWCNTs was also investigated in these transformations. 相似文献
15.
Elham Masoudipour Soheila Kashanian Abbas Hemati Azandaryani Kobra Omidfar Elham Bazyar 《Cellulose (London, England)》2017,24(10):4217-4234
Storage conditions seem to be important in the long-term stability of nanoparticles (NPs). This work studies the effects of surfactants and storage container on particle size distribution and zeta potential during long-term storage of acid hydrolyzed potato starch NPs. The NPs were prepared from potato starch using acid hydrolysis and high-intensity ultrasonication. During the ultrasonic treatment, the surfactants were added dropwise to the solutions to reduce the size and stabilize the formed NPs. Particle size distribution, zeta potential, and FE-SEM were used to characterize the ensuing NPs. Additionally, a 5-month stability study was performed to evaluate the maintenance of potato starch NPs over time at different storage conditions. Then, NPs from corn starch were produced by the same procedure and were used for preparing pH-responsive nanocarriers containing NaHCO3 for delivery of an anti-cancer drug, FTY720. These NPs were able to release the drug at pH 5.0 because of CO2 generated from NaHCO3 in acidic pH and released from the NPs by the production of pores, which accelerate drug release. 相似文献
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Seyyed Hossein Miraghaie Ashkan Zandi Zahra Davari Mohamad Sadegh Mousavi-kiasary Zohre Saghafi Ali Gilani Yasin Kordehlachin Fatemeh Shojaeian Amir Mamdouh Zahra Heydari Farid Abedin Dorkoosh Babak Kaffashi Mohammad Abdolahad 《Macromolecular bioscience》2023,23(9):2300181
Pure positive electrostatic charges (PPECs) show suppressive effect on the proliferation and metabolism of invasive cancer cells without affecting normal tissues. PPECs are used for the delivery of drug-loaded polymeric nanoparticles (DLNs) capped with negatively charged poly(lactide-co-glycolide) (PLGA) and Poly(vinyl-alcohol) PVA into the tumor site of mouse models. The charged patch is installed on top of the skin in the mouse models' tumor region, and the controlled selective release of the drug is assayed by biochemical, radiological, and histological experiments on both tumorized models and normal rats' livers. It is found that DLNs synthesized by PLGA show great attraction to PPECs due to their stable negative charges, which would not degrade immediately in blood. The burst and drug release after less than 48h of this synthesized DLNs are 10% and 50%, respectively. These compounds can deliver the loaded-drug into the tumor site with the assistance of PPECs, and the targeted-retarded release will take place. Hence, local therapy can be achieved with much lower drug concentration (conventional chemotherapy [2 mg kg−1] versus DLNs-based chemotherapy [0.75 mg kg−1]) with negligible side effects in non-targeted organs. PPECs have many potential clinical applications for advanced-targeted chemotherapy with the lowest discernible side effects. 相似文献
19.
Investigation of substituent effects in aerogen‐bonding interaction between ZO3 (Z=Kr,Xe) and nitrogen bases
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Mehdi D. Esrafili Soheila Asadollahi Mahshad Vakili 《International journal of quantum chemistry》2016,116(16):1254-1260
The substituent effects in aerogen bond interactions between ZO3 (Z = Kr, Xe) and different nitrogen bases are studied at the MP2/aug‐cc‐pVTZ level of theory. The nitrogen bases include the sp bases NCH, NCF, NCCl, NCBr, NCCN, NCOH, NCCH3 and the sp3 bases NH3, NH2F, NH2Cl, NH2Br, NH2CN, NH2OH, and NH2CH3. The nature of aerogen bonds in these complexes is analyzed by means of molecular electrostatic potential, electron localization function, quantum theory atoms in molecules, noncovalent interaction index, and natural bond orbital analyses. The interaction energy (Eint) ranges from ?4.59 to ?9.65 kcal/mol in the O3Z···NCX complexes and from ?5.30 to ?13.57 kcal/mol in the O3Z···NH2X ones. The dominant charge‐transfer interaction in these complexes occurs across the aerogen bond from the nitrogen lone‐pair (nN) of the Lewis base to the σ*Z‐O antibonding orbital of the ZO3. Besides, the formation of aerogen bond tends to decrease the 83Kr or 131Xe chemical shielding values in these complexes. © 2016 Wiley Periodicals, Inc. 相似文献
20.
Shamsipur M Dastjerdi LS Haghgoo S Armspach D Matt D Aboul-Enein HY 《Analytica chimica acta》2007,601(1):130-138
19F NMR spectroscopy was applied to the quantitative determination of fluoxetine enantiomers using different chiral recognition agents in pharmaceutical formulations. Several parameters affecting the enantioresolution including the type and concentration of chiral selector, concentration of fluoxetine and temperature were studied. The chiral selectors investigated are the cyclic oligosaccharides α-, β- and γ-cyclodextrin and a diamino derivative of methylated α-cyclodextrin (DAM-α-CD), linear polysaccharides (maltodextrin with dextrose equivalents of 4.0-7.0, 13.0-17.0 and 16.5-19.5) and the macrocyclic antibiotic vancomycin. Among the chiral selectors used, DAM-α-CD turned out to give the best resolution of the 19F NMR signals of (R)- and (S)-fluoxetine. The calibration curve was linear for (R)- and (S)-fluoxetine over the range 0.10-1.35 mg mL−1, the detection limits (S/N = 3) being 5.9 and 7.5 μg mL−1 for the pure solutions of (R)- and (S)-fluoxetine, respectively. The recovery studies performed on pharmaceutical samples ranged from about 90 to 110% with relative standard deviations of <8%. The results showed that the proposed method is rapid, precise and accurate. Applying statistical Student's t-test revealed insignificant difference between the real and measured contents at the 95% confidence level. 相似文献