We deal with the scattering of an acoustic medium modeled by an index of refraction n varying in a bounded region Ω of and equal to unity outside Ω. This region is perforated with an extremely large number of small holes Dm's of maximum radius a, a << 1, modeled by surface impedance functions. Precisely, we are in the regime described by the number of holes of the order M:=O(aβ ? 2), the minimum distance between the holes is d ~ at, and the surface impedance functions of the form λm~λm,0a?β with β > 0 and λm,0 being constants and eventually complex numbers. Under some natural conditions on the parameters β,t, and λm,0, we characterize the equivalent medium generating approximately the same scattered waves as the original perforated acoustic medium. We give an explicit error estimate between the scattered waves generated by the perforated medium and the equivalent one, respectively, as a→0. As applications of these results, we discuss the following findings: 相似文献
The alpha-alkylation of amide enolates by using a pseudo-C(2) symmetry trans 4-phenyl-2-trifluoromethyloxazolidine (trans-Fox) as a chiral auxiliary occurs with an extremely high diastereoselectivity (>99 % de). The origin of this excellent stereocontrol was investigated by an experimental and theoretical (DFT) study. With this trans chiral auxiliary, both F...metal and pi...metal interactions compete to give the same diastereomer through Re face alkylation of the enolate. A 5.5 kcal mol(-1) energy difference found between the Re face and the Si face attack transition states is consistent with the complete diastereoselectivity that has been experimentally achieved. On the other hand, in the case of the cis chiral auxiliary (cis-Fox) the competition between the F...metal and pi...metal interactions is unfavourable to the diastereoselectivity. In this case, the Re face and the Si face attack transition states were found to be nearly isoenergetic (0.3 kcal mol(-1) difference), which is in good agreement with the very low diastereoselectivity observed. 相似文献
This work is concerned with the inverse problem for ocean acoustics modeled by a multilayered waveguide with a finite depth. We provide explicit formulae to locate the layers, including the seabed, and reconstruct the speed of sound and the densities in each layer from measurements collected on the surface of the waveguide. We proceed in two steps. First, we use Gaussian type excitations on the upper surface of the waveguide and then from the corresponding scattered fields, collected on the same surface, we recover the boundary spectral data of the related 1D spectral problem. Second, from these spectral data, we reconstruct the values of the normal derivatives of the singular solutions, of the original waveguide problem, on that upper surface. Finally, we derive formulae to reconstruct the layers from these values based on the asymptotic expansion of these singular solutions in terms of the source points. 相似文献
A numerical study using improved delayed detached eddy simulation (IDDES) was used to investigate the influence of the embankment height on the aerodynamic performance of a high-speed train travelling under the influence of a crosswind. The results of the flow predictions were used to explore both the instantaneous and the time-averaged flows and the resulting aerodynamic forces, moments and slipstreams. An increase of the aerodynamic drag and side forces as well as the lift force of the head and middle cars were observed with rising embankment height. While the lift force of the tail car decreased with the increasing embankment height. Furthermore, the height of the embankment was found to have a strong influence on the slipstream on the leeward side of the train. The correlation between the embankment height and the slipstream velocity on the windward side, was rather small. The flow structures in the near-wake of the leeward side of the train, responsible for the aerodynamic properties of the train were analyzed, showing strong dependency on the embankment height.
The treatment of Parkinson’s disease is often complicated by levodopa-induced dyskinesia (LID). Nicotinic acetylcholine receptor agonists can alleviate LID in animal models but may be less effective in conditions of severe dopaminergic denervation. While the mechanisms of LID remain incompletely understood, elevated corticostriatal levels of the brain-derived neurotrophic factor (BDNF) have been suggested to play a role. Here, female mice with near-total unilateral 6-hydroxydopamine-induced nigrostriatal lesions were chronically treated with levodopa, and the effects of the α7 nicotinic receptor partial agonist AZD0328 and nicotine on LID were assessed. At the end of the experiment, BDNF protein levels in the prefrontal cortex and striatum were measured.
Results
Five-day treatments with three escalating doses of AZD0328 and a 10-week treatment with nicotine failed to alleviate LID. BDNF levels in the lesioned striatum correlated positively with LID severity, but no evidence was found for a levodopa-induced elevation of corticostriatal BDNF in the lesioned hemisphere. The nicotine treatment decreased BDNF levels in the prefrontal cortex but had no effect on striatal BDNF.
Conclusions
The findings suggest that treatment of LID with nicotinic agonists may lose its effectiveness as the disease progresses, represent further evidence for a role for BDNF in LID, and expand previous knowledge on the effects of long-term nicotine treatment on BDNF.
In this paper we present numerical simulations for the dam-break flood wave propagation from Tribalj accumulation to the town
of Crikvenica (Croatia). The mathematical models we used were the one-dimensional open channel flow and the two-dimensional
shallow water equations. They were solved with the well-balanced finite volume numerical schemes which additionally include
special numerical treatment of the wetting/drying front boundary. These schemes were tested on CADAM test problems. The aim
of this study was to assess potential damage in the village of Tribalj and the town of Crikvenica. Results of these simulations
were used as the basis for urban planning and micro-zoning of the flood-risk areas. Several different dam-break scenarios
were considered, ranging from sudden dam disappearance to partial and dynamic breach formation.
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We develop a No Response Test for the reconstruction of a polyhedral obstacle from two or few time-harmonic electromagnetic incident waves in electromagnetics. The basic idea of the test is to probe some region in space with waves which are small on some test domain and, thus, do not generate a response when the scatterer is inside of this test domain. We will prove that the No Response Test checks analytic continuability of a time-harmonic field from the far field pattern into the domain for a non-vibrating test domain B.We show that two incident waves, defined by one incident direction and two appropriately chosen directions of polarization, are enough to recover the convex hull of polyhedrals. Based on this uniqueness result, we build up the No Response Test and we prove convergence in the sense that it fully reconstructs a convex polyhedral scatterer D or the convex hull of an arbitrary polyhedral scatterer.Further, we will describe the algorithmic realization of the No Response Test and show the feasibility of the method by reconstruction of convex polyhedral objects in three dimensions. This is the first formulation of the No Response Test for electromagnetics. 相似文献