Constituents from Rubia Ustulata Diels and R. Yunnanensis Diels and Their Antiplatelet Aggregation Activity

A new anthraquinone glycoside, rubiayannone‐A ( 1 ), and a new coumarin, rubilatin‐A ( 2 ), together with twenty‐two known compounds were isolated and characterized from the roots of Rubia ustulata. A new anthraquinone, 2‐carbomethoxyanthraquinone ( 3 ), and rubiayannone‐A, 2‐formylanthraquinone were obtained from the roots of R. yunnanensis. The structures of those compounds were elucidated by spectroscopic methods. The antiplatelet aggregation activity of the isolated compounds 1, 4～6 were also discussed.     

Electrocatalytic Oxidation of Dopamine by Ferrocene in Lipid Film Cast on a Glassy Carbon Electrode

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Uniform hierarchical silica film with perpendicular macroporous channels and accessible ordered mesopores for biomolecule separation

Herein, we demonstrate that silica films with perpendicular macroporous channels and accessible ordered mesopores can be conveniently prepared. The hierarchical macroporous–mesoporous silica films are synthesized by using zinc oxide nanorod array as macroporous template and CTAB surfactant as mesoporous template. In basic surfactant-containing solution, ordered mesoporous silica shells homogeneously grow on the zinc oxide nanorod array. The growth of the mesostructures do not require any chemical modification for the zinc oxide nanorod, which opens a new way for preparing hierarchical silica films with perpendicular mesochannels. The prepared hierarchical macroporous–mesoporous silica films possess a uniform thickness of 2 mm, large perpendicular macropores with a length of 1.8 mm and a width of 80 nm, and accessible ordered mesopores. Separation experiment demonstrates that this macroporous–mesoporous film can effectively separate biomolecules with different sizes.     

Interaction of zinc finger ZNF191(243—368) and its I323 W and R327W mutants with oligonucleotides by florescence spectrum

Two mutants of the zinc finger protein, ZNF191 (243–368) I323W and R327W, are successfully obtained by site-directed mutagenesis. The fluorescence spectrum is used to study the interaction between these two mutants and the oligonucleotides. The influence of the mutation on the interaction has been studied using ethidium bromide (EB) as the fluorescence probe. The binding constants of the I323W-DNA and R327W-DNA have been calculated and the possible binding models have been discussed.     

meso-substituted aromatic 34pi core-modified octaphyrins: syntheses,characterization and anion binding properties

Modified octaphyrins with 34pi electrons have been synthesized and characterized following a simple synthetic methodology. An acid-catalyzed alpha,alpha coupling of tetrapyrranes containing furan, thiophene and selenophene rings resulted in the formation of the respective octaphyrins in relatively good yield. Solution studies by (1)H NMR and 2D NMR methods and single crystal Xray structural characterization reveal an almost flat structure with two heterocyclic rings inverted. Specifically, in 14 two selenophene rings (one on each biselenophene unit) are inverted while in 15 two furan rings (one on each bifuran unit) are inverted when the meso substituent are mesityl groups. On changing the mesityl substituent to m-xylyl group as in 19, the location of ring inversion shifts to pyrrole rings (one on each bipyrrole unit) indicating the dependence of structure on the meso substituents. UV/Vis studies, both in freebase and protonated forms reveal typical porphyrinic character and the aromatic nature of the octaphyrins. The Deltadelta values evaluated by (1)H NMR spectroscopy also support their aromatic nature. The protonated forms of octaphyrins bind TFA anion in a 1:2 ratio. The TFA anions are located one above and below the plane of the octaphyrin macrocycle and they are held by weak electrostatic NH-O interactions similar to that observed for protonated rubyrins. However, in the present case, there is an additional non-electrostatic CH-O interaction involving beta-CH of the inverted heterocyclic ring and the carbonyl oxygen of the TFA. Furthermore, inter molecular interactions between the Cbond;H of the meso-mesityl group and the fluorine of CF(3) group of bound TFA leads to the formation of one-dimensional supramolecular arrays with interplanar distance of 13 A between two octaphyrins.     

Novel bismaleimide containing cyclic phosphine oxide and an epoxy unit: Synthesis, characterization, thermal and flame properties

A new type of bismaleimide resin (EPBMI), containing epoxy unit and phosphorus in the main chain, was synthesized. The structure of the new resin was confirmed by infrared spectroscopy (IR), ¹H NMR and ¹³C NMR spectroscopies. In addition, the compositions of the new synthesized bismaleimide with two reactants, 4,4′-diaminodiphenylsulfone (DDS) and 4,4′-diaminodiphenylether (DDE), was used to compare its reactivity and thermal properties with conventional bismaleimide (EBMI). Reactivity was measured by differential scanning calorimetry. Thermogravimetric analysis revealed that the polymers, obtained through the reactions between bismaleimides and diamine agents, also demonstrated excellent thermal properties and high char yield.     

Radical-induced formation of some siloles and diazasiloles

The Bu(3)Sn radical-induced reaction of o-iodobenzylvinylsilanes and o-iodoallylsilanes leads to cyclic products in yields of 40-60%. These regioselective cyclizations occur with high preference for a 5-exo and a 7-endo mode with a 6-exo mode being absent. An example for ring closure via a 7-exo mode is described.     

Characterization of Roasting Time on Sensory Quality,Color, Taste,and Nonvolatile Compounds of Yuan An Yellow Tea

Roasting is crucial for producing Yuan An yellow tea (YAYT) as it substantially affects sensory quality. However, the effect of roasting time on YAYT flavor quality is not clear. To investigate the effect of roasting time on the sensory qualities, chemical components, odor profiles, and metabolic profile of YAYTs produced with 13 min roasting, 16 min roasting, 19 min roasting, 22 min roasting, and 25 min roasting were determined. The YAYTs roasted for 22 min got higher sensory scores and better chemical qualities, such as the content of gallocatechin (GC), gallocatechin gallate (GCG), free amino acids, solutable sugar, meanwhile the lightness decreased, the hue of tea brew color (b) increased, which meant the tea brew got darker and yellower. YAYTs roasted for 22 min also increased the contents of key odorants, such as benzaldehyde, nonanal, β-cyclocitral, linalool, nerol, α-cedrol, β-ionone, limonene, 2-methylfuran, indole, and longiborneol. Moreover, non-targeted metabolomics identified up to 14 differentially expressed metabolites through pair-wise comparisons, such as flavonoids, phenolic acids, sucrose, and critical metabolites, which were the main components corresponding to YAYT roasted for 22 min. In summary, the current results provide scientific guidance for the production of high quality YAYT.     

一种用于电子纸的电泳液的显示性能研究

用有机颜料汉沙黄(P.Y.3)、苏丹黑和合适的稳定剂为原料配制了一种性能稳定的电泳显示液.分析了此电泳显示液中颜料微粒的带电机理及其影响因素,研究了在改变电压方向时反射光谱与吸收光谱的变化及其原因,光谱分析结果表明体系中存在的各种吸附使显示效果受到局限,反射谱与吸收谱的变化在表征器件的显示特性时呈现出一致性,器件的反射光强和反射率在不同波长上有区域选择性,同时对比度也有区域选择性,这决定了在监测器件的响应时应选择的波长范围以及可利用的光源.兼顾灵敏性和测试信号强度的需求,选用峰值波长为470 nm的蓝光二极管为光源,电泳槽的厚度为0.2 mm,用荧光光谱仪监测相同周期不同幅值脉冲电压作用下颜料微粒在493 nm波长处的反射光强的变化,并由示波器记录并输出反射光强随驱动电压的变化,还结合相关理论讨论了驱动电压对器件的反射光强和对比度的影响.