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很多致命的疾病都与细菌感染密切相关,快速、准确地检测和鉴定细菌及微生物,一直是微生物学家及有关科研工作者追求的目标,拉曼光谱可以提供丰富的谱图信息,而表面增强拉曼光谱(SERS)有很高的检测灵敏度,然而一些贵金属SERS基底却容易使蛋白质变性,影响检测结果。以大肠杆菌(E.Coli)作为目标检测细菌,首先检测到大肠杆菌的拉曼光谱,之后采用两种不同的SERS基底(ZnO,Ag溶胶)进行检测。结果表明Ag溶胶基底有很强且较丰富的SERS信号,但是相对于E.Coli的本体拉曼谱峰有较大位移,说明与银溶胶相互作用的细菌存在一定的蛋白质变性过程;而ZnO纳米粒子与细菌作用的SERS信号虽然较弱,但是与E.Coli的本体拉曼信号较为相似,说明ZnO纳米粒子对E.Coli本体基本无损,这将有利于SERS在生物体系的无损检测。该结果可以为利用生物相容性好的半导体SERS基底进行细菌的检测提供有益的参考。 相似文献
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A proton radiography system is an accelerator-based facility.Especially high-energy proton radiography is an advanced hydrodynamics diagnostic tool,and it is the trend of radiography technology development.In this paper,a 20 GeV accelerator complex scenario,including a 35 MeV linac,a 1 GeV booster and a 20 GeV main ring,is introduced.The overall physics design of the proton radiography accelerator is described,including the design of each part of the accelerator and the choice of the main parameters. 相似文献
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Jiafu Wang Shaobo Qu Zhuo Xu Hua Ma Xinhua Wang Daqing Huang Yongfeng Li 《Photonics and Nanostructures》2012,10(4):540-546
We demonstrated the possibility of designing super-thin electromagnetic cloaks based on spoof surface plasmon (SSP). Using a metamaterial layer, incident waves can be coupled into SSP efficiently at the air/metamaterial interface. Due to the strong surface confinement of SSP, EM waves are squeezed into and propagate in deep sub-wavelength scales. Implementation of an 8.2 GHz cloak less than 1/50 the cloaking diameter was presented using split ring resonator (SRR). Excellent cloaking effect was verified by simulations. Rather than isolating objects from the background, such cloaks can drastically enhance the field intensity around the cloaked object. This is of particular importance in applications such as weak wave detection and near-field sensing. 相似文献
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Magnifying magnetic lenses can be used in high-energy proton microscopes. The -I lens suggested by Zumbro is analyzed in this paper, and a new type of magnetic lens called a lengthened lens is introduced. Theoretical analysis shows that the lengthened lens can form a magnifying lens, and at the same time the main advantages of a Zumbro lens are inherited. Using the My-BOC beam dynamics code, an example of the design is shown. The results show that the method of designing magnifying magnetic lenses is effective. 相似文献
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Wavelength tunable passively Q-switched Yb-doped double-clad f iber laser with graphene grown on SiC
Liqiang Zhang Zhuang Zhuo Rusheng Wei Yunzheng Wang Xiufang Chen Xiangang Xu 《中国光学快报(英文版)》2014,12(2):21405-53
A passively Q-switched tunable Yb-doped double-clad fiber laser is demonstrated with graphene epitaxially grown on SiC.The spectral tuning of the Q-switched fiber laser is implemented by rotating a quartz plate filter inside the cavity.The central wavelength of the fiber laser can be continuously tuned from 1038.54 to 1056.22 nm.The maximum pulse energy of 0.65 μJ is obtained at the pump power of 4.08 W,and the corresponding pulse duration and average output power are 1.60 μs and 35 mW,respectively. 相似文献
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The eigensystem realisation algorithm (ERA) is one of the most popular methods in civil engineering applications for estimating modal parameters. Three issues have been addressed in the paper: spurious mode elimination, estimating the energy relationship between different modes, and automatic analysis of the stabilisation diagram. On spurious mode elimination, a new criterion, modal similarity index (MSI) is proposed to measure the reliability of the modes obtained by ERA. On estimating the energy relationship between different modes, the mode energy level (MEL) was introduced to measure the energy contribution of each mode, which can be used to indicate the dominant mode. On automatic analysis of the stabilisation diagram, an automation of the mode selection process based on a hierarchical clustering algorithm was developed. An experimental example of the parameter estimation for the Chaotianmen bridge model in Chongqing, China, is presented to demonstrate the efficacy of the proposed method. 相似文献