Responses of Issatchenkia terricola WJL-G4 upon Citric Acid Stress

This study aimed to elucidate the responses of a novel characterized Issatchenkia terricola WJL-G4 against citric acid stress by performing physiological analysis, morphology observation, and structural and membrane fatty acid composition analysis. The results showed that under citric acid stress, the cell vitality of I. terricola WJL-G4 was reduced. The cell morphology changed with the unclear, uncompleted and thinner cell wall, and degraded the cell structure. When the citric acid concentration was 20 g/L, I. terricola WJL-G4 could tolerate citric acid and maintain the cell structure by increasing the intracellular pH, superoxide dismutase activity, and contents of unsaturated fatty acids. As the citric acid concentration was ≥80 g/L, the stress has exceeded the cellular anti-stress ability, causing substantial cell damage. The cell membrane permeability, the content of membrane lipids, malondialdehyde and superoxide anion increased, but the intracellular pH and superoxide dismutase activities decreased, accompanying the increase of citric acid concentrations. The findings of this work provided a theoretical basis for the responsive mechanism of I. terricola WJL-G4 under high concentrations of citric acid, and can serve as a reference for biological acid reduction in fruit processing.     

Synthesis, Structure and H+/K+-ATPase Inhibitory Activity of Novel Triazolyl Substituted Tetrahydrobenzofuran Derivatives via One-pot Three-component Click Reaction

Eleven triazolyl substituted tetrahydrobenzofuran derivatives were synthesized in high yields as novel H⁺/K⁺‐ATPase inhibitor via one‐pot CuI‐catalyzed three‐component click reaction of azide, secondary amine and 3‐bromopropyne under mild conditions in water. Their structures were characterized by NMR, IR, ESI‐MS, elemental analysis and single‐crystal X‐ray diffraction analysis. Most of the target compounds exhibited better H⁺/K⁺‐ATPase inhibitory activity than commercial omeprazole with IC₅₀ values less than 15 µmol·L^?1. The initial structure‐activity analysis suggested that the triazole substituted by cycloalkyl, aromatic ring or O‐containing side‐chain seemed to be beneficial for enhancing the activity.     

Development of Sn2+-based oxyfluoride photocatalyst with visible light response of ca.650 nm via strengthened hybridization of Sn 5s and 02p orbitals

The hybridization between the outmost s orbitals of metal (Bi3+,Sn2+,Pb2+,Ag+) and O 2p orbitals has been widely employed to develop innovative semiconductors w...     

Diffraction integral for misaligned systems and interference effects of optical arrays

Summary In the present paper, a diffraction integral formula for a misaligned optical system is derived. The interference effects of opticalelement arrays are studied by means of such a formula. The possibility of eliminating interference fringes is discussed. The conclusion is that the interference fringes could be eliminated when the αβγδ condition for arrays is satisfied. The synthetical aberration is simultaneously eliminated. However, in this case, the synthetical image coincides with the individual images. For some special application, the synthetical image does not coincide with the individual images and the αβγδ condition is not fulfilled. But the interference fringes may disappear in some special cases.

---

Riassunto La formula di Collins, che esprime il cammino ottico fra un punto del piano oggetto e un punto del piano immagine nel caso di un sistema ottico centrato, è generalizzata al caso di un sistema ottico disallineato. La formula cosí ottenuta è applicata allo studio del fenomeno d’interferenza che ha luogo nel piano della cosiddetta ?immagine sintetica? fra i vari fasci emergenti da una cortina di elementi ottici. Si discutono infine le condizioni in cui non si hanno frange d’interferenza sull’immagine sintetica.

     

小世界生物神经网络的相干共振研究

研究了无外界周期信号时Hodgkin-Huxley模型小世界生物神经网络的非线性响应.数值模拟结果显示：当噪声强度取某一有限值时,峰序列有序度可以达到最大,即产生相干共振现象.同时发现： 随着网络规模N的变化,相干共振系数cv的极小值不是一个,而是多个.这表明相干共振可发生在神经元集群数目特定的不同规模的网络中. 关键词： 相干共振 有序度 小世界网络 生物神经网络     

256色模式下调色板的匹配

在计算机屏幕上同时显示两幅颜色相差较大、调色板各异的图像，需要匹配两幅图像的调色板．本文引入了两种匹配算法：颜色中和算法和颜色分类算法，并分别详述这两种算法的基本原理和在２５６色模式下的实现方法．     

盐生盐杆菌灭活原生质体融合的研究

通过双亲灭活方法将二株具不同遗传学特性的盐生盐杆菌Ｊ７（含质粒，不产紫膜）和Ｒ１（产紫膜，不含质粒）进行原生质体融合试验．结果表明，在以３０％ＰＥＧ６００为助融剂，加２５ｍｍｏｌ·Ｌ－１ＥＤＴＡ条件下，４０℃保温１ｍｉｎ，获得融合率为０．７６×１０－５的融合子．这些融合子具有双亲菌株的某些特征，其中２２％的融合子既含有质粒又产紫膜，这些融合子对于进一步研究质粒与紫膜的关系，以及筛选高产紫膜的优良菌株，均有十分重要的价值．