诺氟沙星与DNA的拉曼光谱研究

报道了诺氟沙星(NFX)及诺氟沙星胶囊内容物的FT-Raman光谱和在银胶基底上的表面增强拉曼光谱(SERS),归属了各个振动;研究了诺氟沙星与DNA的相互作用的SERS,结果表明:胶囊内容物的拉曼光谱图与对照品的拉曼光谱图的特征振动峰:C-F键的伸缩振动,C=C伸缩振动,O-C-O的对称伸缩振动峰值未发生变化,发生变化主要是分子骨架振动峰,诺氟沙星胶囊的辅料对拉曼光谱无实质影响,可建立拉曼光谱法检测诺氟沙星药物的分析方法;诺氟沙星可以在没有金属离子的存在下与DNA直接作用,与DNA相互作用的主要键合模式是插入作用,NFX分子中的平面结构插入DNA的双螺旋碱基平面,为深入了解喹诺酮类抗生素的抗菌机理提供可靠依据.     

工科物理实验教学改革的实践与探索

介绍了近年来华中科技大学物理实验中心教学改革的历程及构建物理实验创新基地的思路和体会．     

Numerical studies of penetration problems by an improved particle method

A particle mapping transportation algorithm was proposed on the basis of the particle-in-cell method.The particles with rectangular influence domains were employed in the transportation algorithm to reduce the numerical fluctuations.Based on the error analysis in the process of particle motion computation,a prediction-correction algorithm was introduced to improve the computational accuracy.Furthermore,the performance of the particle mapping transportation method was evaluated by using the rotation,the slotted disk and the shear advection tests,and the results were compared with other interface reconstruction methods.Finally,the hemispherical projectile penetration into a steel target was numerically simulated.The results showed that the proposed method produced less numerical fluctuations and exhibited clear material interfaces,which indicated that it is accurate and effective.     

A New Variational Study for Two-Site Holstein Model

A variational approach is developed to study the groundstate (GS) of the two-site Holstein model. By the extended coherent state, where the more phonon correlations are easily incorporated, we can get the very accurate ground state energy for all electron-phonon coupling range in typical values of hopping integral t=0.5,1.1, and 2.1 (in units of phonon frequency ω₀), which covers the crossover region from antiadiabatic limit to the adiabatic limit. Within a very wide t range [0,2.7], the exact results for the GS energy are obtained with the twelfth (fourteenth) order corrections to the zeroth order wave function. Moreover, the present approach is more concise than any other analytical ones in this field, and hopefully can be easily generalized to many other Holstein models.     

CaO/稻壳灰作为新型CO2吸收剂的循环碳酸化特性

提出了采用CaO与稻壳灰的水合产物作为新型CO2吸收剂.研究表明,当水合时间为8 h、水合温度为75℃和Si/Ca摩尔比为1.0时, CaO/稻壳灰吸收剂能获得最佳循环碳酸化转化率;经过20次循环反应碳酸化转化率可达0.44,比相同反应条件下CaO/H2O吸收剂的转化率提高了42%,是原CaO转化率的2倍.650～700℃时有利于CaO/稻壳灰的碳酸化反应;在高煅烧温度下比CaO/H2O和CaO具有更好的抗烧结能力.     

基于分数阶傅立叶变换的线性调频回波参数估计

本文提出了一种适用于宽带线性调频回波的分数阶傅立叶变换参数估计方法。它通过寻找合适的信号代替发射信号做模版,使得模版信号与接收信号的模糊函数匹配度高,峰值尖锐,失真率低。再利用分数阶傅立叶变换与模糊函数的关系,使用两次分数阶域的峰值搜索代替原有的一次二维搜索降低计算量。仿真实验结果表明,本文提出的方法在精确估计宽带回波的时延和频移的同时降低了计算复杂度。     

光孤子对的振幅比与相位差对传输的影响

利用分步傅里叶变换法分别求解含三阶色散效应和不考虑三阶色散情况下的光孤子非线性薛定谔（NLS）方程,通过数值求解发现三阶色散效应会使孤子对脉冲发生单边振荡,并在振荡侧逐级产生次脉冲。讨论孤子对的两束孤子脉冲之间的振幅比与相位差对传输的影响,发现在不考虑三阶色散的情况下,振幅比与相位差均对孤子对的传输有显著影响,在考虑三阶色散效应时,只有相位差对孤子对的传输产生影响,并可以导致脉冲能量转移。     

Branch Processes of Regular Magnetic Monopole

In this paper, by making use of Duan＇s topological current theory, the branch process of regular magnetic monopoles is discussed in detail. Regular magnetic monopoles are found generating or annihilating at the limit point and encountering, splitting, or merging at the bifurcation point and the degenerate point systematically of the vector order parameter field φ（x）. Furthermore, it is also shown that when regular magnetic monopoles split or merge at the degenerate point of field function φ, the total topological charges of the regular magnetic monopoles are stilI unchanged.     

Evolution of Spiral Waves in Excitable Systems

Spiral waves, whose rotation center can be regarded as a point defect, widely exist in various two-dimensional excitable systems. In this paper, by making use of Duan＇s topological current theory, we obtain the charge density of spiral waves and the topological inner structure of its topological charge. The evolution of spiral wave is also studied from the topological properties of a two-dimensional vector field. The spiral waves are found generating or annihilating at the limit points and encountering, splitting, or merging at the bifurcation points of the two-dimensional vector field. Some applications of our theory are also discussed.     

微波辐射法合成N-苯基马来酰亚胺

用微波辐射法合成N-苯基马来酰亚胺,在总结前人对原料配比、催化剂用量对反应收率影响的基础上,本实验以顺丁烯二酸酐和苯胺为原料用醋酐作脱水剂、醋酸钠作催化剂采用微波辐射法两步合成N-苯基马来酰亚胺。探讨最佳工艺条件为第一步用微波功率80W熟化3min,第二步用微波以功率400W加热1.5min时N-苯基马来酰亚胺的收率可达75.8%。产品经晶形、熔点和红外光谱分析确定为目标产品。