310.
During studies on the structure? pesticidal‐activity relationship of
Azadirachta indica constituents, azadiradione ( 1 ) was treated with methanolic K
2CO
3 to obtain 7‐deacetyl derivative nimbocinol ( 2 ). Unexpectedly, 17
β‐hydroxynimbocinol ( 3 ), reported earlier as a natural product, was also formed. The structure? pesticidal‐activity relationship of triterpenoids 1 – 16 against
Anopheles stephensi Liston is described towards understanding the active functionalities responsible for the pesticidal activity of triterpenoids having apoeuphane(apotirucallane) and gedunin skeleta. The pesticidal activities of triterpenoids 2 – 8 are reported for the first time.
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