1β,10α-Dihydroxyarglabin — A new sesquiterpene lactone fromArtemisia glabella

The new sesquiterpene lactone 1β,10α-dihydroxydihydroxyarglabin has been isolated from the epigeal part ofArtemisia glabella Kar. et Kir., and its structure has been established on the basis of spectral characteristics, independent synthesis, arglabin, and an x-ray structural investigation. Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 825–830, November–December, 1993.     

One-Step Synthesis of the Vicinal Dinitroguaianolides Achillin and Grossmisin

1,10-Dihydro-1,10-dinitrogrossmisin was synthesized by bubbling gaseous nitrosyl chloride through a chloroform solution of the guaianolide grossmisin. The molecular structure was determined by X-ray. It was found that the formation of similar dinitrates is accelerated by using NOCl containing nitrogen dioxide.     

Production of Lypoglycoprotein Micelles with Arglabine Antitumor Preparation

The possible production of a new medicinal form of the antitumor preparation arglabine was studied by including it in lipoglycoprotein micelles isolated from wheat grains     

Molecular and crystal structure of the sequiterpene lactone austricin

An x-ray structural study has been made of the sesquiterpene lactone austricin: diffractometer, MoK_α radiation, 1147 reflections, direct method, R=0.045. The spatial structure of the molecule has been determined. The conformation of the pentane carbocycle is 1α-envelope, of the heptane ring 1,10β, 7α-chair, and of the lactone ring 7α-envelope. The lactone ring is trans-linked with the guaiane skeleton. Institute of Organic Synthesis and Coal Chemistry, Kazakh SSR Academy of Sciences, Karaganda. A. N. Nesmeyanov Institute of Heteroorganic Compounds, USSR Academy of Sciences, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 788–791, November–December, 1989.