排序方式: 共有64条查询结果,搜索用时 15 毫秒
51.
Russian Journal of General Chemistry - A series of novel 1,3,4-oxadiazole fused pyridine derivatives were synthesized 11a–11f and their structures confirmed by IR, 1H NMR and Mass spectral... 相似文献
52.
N. J. P. Subhashini P. Janaki B. Bhadraiah 《Russian Journal of General Chemistry》2017,87(9):2021-2026
A series of benzofuran hydrazones 6a–6n were synthesized from benzofuran aldehyde and substituted aromatic hydrazides 5a–5n. Structures of all compounds were confimed by IR, 1H and 13C NMR, and Mass spectral data. These compounds were evaluated for their antibacterial activity against gram-negative bacteria (Escherichia coli, –ve), gram-positive bacteria (Bacillus Subtillis, +ve), and antifungal activity against Candida albicans. All compounds demonstrated considerable activity against bacteria and fungi. 相似文献
53.
This review article expands on the previous one (Jmeian, Y. and El Rassi, Z. Electrophoresis 2009, 30, 249-261) by reviewing pertinent literature in the period extending from early 2008 to the present. Similar to the previous review article, the present one is concerned with proteomic sample preparation (e.g. depletion of high-abundance proteins, reduction of the protein dynamic concentration range, enrichment of a particular subproteome), and the subsequent chromatographic and/or electrophoretic prefractionation prior to peptide separation and identification by LC-MS/MS. This review article differs from the first version published in Electrophoresis 2009, 30, 249-261 by expanding on capturing/enriching subglycoproteomics by lectin affinity chromatography. Ninety-eight articles published in the period extending from early 2008 to the present have been reviewed. By no means is this review article exhaustive: its aim is to give a concise report on the latest developments in the field. 相似文献
54.
Subhashini N. J. P. Jilla L. Kolluri P. Kumar 《Russian Journal of General Chemistry》2020,90(10):1960-1967
Russian Journal of General Chemistry - Novel benzosuberone-quinazolinones hybrids have been synthesized efficiently in high yields, and their structures have been confirmed by1H and 13C NMR,... 相似文献
55.
High resolution 1H and 13C NMR spectra of four 3-ethyl-4-hydroxy- 4-phenylpiperidines 1-4 have been recorded in CDCl3 and analysed. The conformations of phenyl and hydroxyl groups at C(4) and ethyl group at C(3) were analysed in detail. The chemical shift of the methyl protons in the ethyl group are quite surprising; they are close to TMS in CDCl(3) and even negative in DMSO-d6. These results are interpreted in terms of the magnetic anisotropy of the phenyl rings at C(2) and C(4) which, in turn, depend on the conformations of the ethyl group at C(3) and the hydroxyl group at C(4). Favoured conformations of ethyl group at C(3) and hydroxyl group at C(4) were calculated by AM1 methods. 相似文献
56.
Electroreduction of Nitroaromatic Compounds at Electrochemically Reduced Graphene Oxide Supported Bimetallic Ag@Pd Nanorods Modified Electrodes 下载免费PDF全文
The design and fabrication of nanostructured electrode with high activity at low cost are crucial elements in studying the toxicity of environmental pollutants. Here, we develop a combined step of generating Electrochemically Reduced Graphene Oxide (ERGO) nanosheets on the surface of the glassy carbon electrode where an effective seed mediated growth followed by a galvanic exchange process were introduced for the direct growth of Ag core @Pd shell nanorods (Ag@Pd NRDs). The resulting electrode possesses a large surface area, interconnected porous networks, uniform distribution of bimetallic Ag@Pd NRDs with extremely thin size of Pd generation and good electrical conductivity, which are highly desirable for the electrocatalytic reduction of nitroaromatic compounds (NACs). In the fabrication step, the shell like Cu at the bimetallic NRDs acts as a sacrificial template for forming a thin layer of Pd at Ag NRDs surface by redox replacement reaction. Thus, the resultant Ag@Pd NRDs on ERGO modified electrode was profoundly tested for the electrochemical sensing of NACs with high sensitivity, selectivity and a very low detection limit of 1.8×10?11 M. Differential Pulse Voltammetry (DPV) was used to study the linear range of 4‐nitroaniline (4‐NA) between 1.0×10?9 M and 1.2×10?8 M. The modified electrode exhibits better reproducibility and long term stability. In addition, the modified electrode out performed well in the real sample analysis containing NACs in the presence of different interfering cations and anions. 相似文献
57.
Srihari Pabbaraja Naresh Gantasala Sridhar Ydhyam Hari Krishna Namballa Subhashini Gundeboina Mallikharjuna R. Lambu Sanjeev Meena Dipak Datta 《Tetrahedron letters》2018,59(26):2570-2576
Stereoselective synthesis of twenty (three 12-, five 13- and twelve 14-membered) macrolides and seventeen functionalized 2,6-trans-disubstituted dihydropyran derivatives have been achieved. The key reactions include an Achmatowicz rearrangement, Ferrier-type alkynylation, Yamaguchi macrolactonization and Lindlar’s hydrogenation. Biological screening of the synthesised compounds showed moderate activity against human cancer cell-lines. 相似文献
58.
Proflavine (3,6-diaminoacridine) shows fluorescence emission with lifetime, 4.6 ± 0.2 ns, in all the solvents irrespective of the solvent polarity. To understand this unusual photophysical property, investigations were carried out using steady state and time-resolved fluorescence spectroscopy in the pico- and femtosecond time domain. Molecular geometries in the ground and low-lying excited states of proflavine were examined by complete structural optimization using ab initio quantum chemical computations at HF/6-311++G** and CIS/6-311++G** levels. Time dependent density functional theory (TDDFT) calculations were performed to study the excitation energies in the low-lying excited states. The steady state absorption and emission spectral details of proflavine are found to be influenced by solvents. The femtosecond fluorescence decay of the proflavine in all the solvents follows triexponential function with two ultrafast decay components (τ(1) and τ(2)) in addition to the nanosecond component. The ultrafast decay component, τ(1), is attributed to the solvation dynamics of the particular solvent used. The second ultrafast decay component, τ(2), is found to vary from 50 to 215 ps depending upon the solvent. The amplitudes of the ultrafast decay components vary with the wavelength and show time dependent spectral shift in the emission maximum. The observation is interpreted that the time dependent spectral shift is not only due to solvation dynamics but also due to the existence of more than one emitting state of proflavine in the solvent used. Time resolved area normalized emission spectral (TRANES) analysis shows an isoemissive point, indicating the presence of two emitting states in homogeneous solution. Detailed femtosecond fluorescence decay analysis allows us to isolate the two independent emitting components of the close lying singlet states. The CIS and TDDFT calculations also support the existence of the close lying emitting states. The near constant lifetime observed for proflavine in different solvents is suggested to be due to the similar dipole moments of the ground and the evolved emitting singlet state of the dye from the Franck-Condon excited state. 相似文献
59.
Marri Pradeep Kumar Narendrula Vamsikrishna Gali Ramesh N. J. P. Subhashini Jagadeesh Babu Nanubolu 《Journal of Coordination Chemistry》2017,70(8):1368-1388
Three isoxazole Schiff bases 2-((E)-(3,5-dimethylisoxazol-4-ylimino)methyl)-6-methoxyphenol (L1), 2-((E)-(3,5-dimethylisoxazol-4-ylimino)methyl)-4,6-diiodophenol (L2), 2-((E)-(3,5-dimethylisoxazol-4-ylimino)methyl)-6-bromo-4-chlorophenol (L3), and their Cu(II) complexes [Cu(L1)2] (1), [Cu(L2)2] (2) and [Cu(L3)2] (3) were synthesized. All the complexes have been characterized by elemental analysis, FT-IR, ESI mass, UV-Visible, ESR, TGA, magnetic moments, and single-crystal X-ray diffraction analysis. Based on analytical data, a square planar geometry is assigned to the Cu(II) complexes with N2O2 donors from the Schiff base ligands. The single-crystal X-ray diffraction measurements of 1 and 2 confirmed the square planar geometry. DNA binding studies from electronic absorption titrations, viscosity measurements, and fluorescence quenching studies indicated an intercalation mode of binding of Cu(II) complexes with CT-DNA. DNA cleavage experiments of Cu(II) complexes with supercoiled plasmid pBR322 DNA have also been investigated by agarose gel electrophoresis in the presence of H2O2 (oxidative cleavage) and UV light (photolytic cleavage). The synthesized compounds were screened for antibacterial (Escherichia coli, Pseudomonas putida, Klebsiella pneumoniae, Bacillus subtillis and Staphylococcus aureus) and antifungal (Candida albicans and Aspergillus niger) activities by the paper disk method. The Cu(II) complexes showed better activity than corresponding Schiff bases. 相似文献
60.
The protonation constant of chloramine-B has been determined at pH < 3.3 by an ionexchange method. The value found is 61 +/- 5. 相似文献