Stereoselective synthesis of Boc-protected l-seleno- and tellurolanthionine, l-seleno- and tellurocystine and derivatives

Optically active seleno- and telluro amino acids can be synthesized from serine via its β-lactone with selenides and tellurides under overall retention of the serine stereochemistry. Boc-protected l-selenolanthionine, l-tellurolanthionine, l-selenocystine, l-tellurocystine and l-tellurocysteine derivatives can be obtained in good yields.     

Hans Lieb zum 20. Juli 1947

Ohne Zusammenfassung     

The effect of the presence of other elements on some microscopic tests for the metals

Summary It is apparent from the results of this study that the tests for lead, mercury, copper, cadmium, stannous tin, iron, manganese, nickel, cobalt and zinc in mixtures using the triple nitrite, oxalate, ferrocyanide or mercuri-thiocyanate reagents are not conclusive or reliable due to the interference of the other metals present. A few opportunities for simultaneous identification do present themselves. These could be utilized in schemes of separation.     

PocketPicker: analysis of ligand binding-sites with shape descriptors

Background  

Identification and evaluation of surface binding-pockets and occluded cavities are initial steps in protein structure-based drug design. Characterizing the active site's shape as well as the distribution of surrounding residues plays an important role for a variety of applications such as automated ligand docking or in situ modeling. Comparing the shape similarity of binding site geometries of related proteins provides further insights into the mechanisms of ligand binding.     

Photoinduced,Direct C(sp2)−H Bond Azo Coupling of Imidazoheteroarenes and Imidazoanilines with Aryl Diazonium Salts Catalyzed by Eosin Y

Herein, a greener approach to the eosin Y-Na₂ catalyzed, C(sp²)−H bond azo coupling of imidazoheteroarene with aryl diazonium salts is described, under acid free conditions. This direct photoredox process resulted in the corresponding azo products in good to excellent yields. Besides, this new approach could also be applicable to anilines, which is a poorly reactive substrate by other methods. The main features of this reaction are that it provides high yields and is gram-scalable and applicable to biologically relevant imidazoheteroarenes and -anilines.     

Set characterizations and convex extensions for geometric convex-hull proofs

Mathematical Programming - In the present work, we consider Zuckerberg’s method for geometric convex-hull proofs introduced in Zuckerberg (Oper Res Lett 44(5):625–629, 2016). It has...     

Adsorber Particles with Magnetically-Supported Improved Electrochemical Conversion Behavior for Waste Water Treatment Processes

Micron-sized supraparticles, consisting of a plurality of discrete nano- and microscale functional units, are assembled and fused by means of a droplet extrusion process. By combining nano magnetite, activated carbon, and conductive carbon with a polymeric binder matrix, particles are obtained which unite good magnetic properties, electrical conductivity, and adsorber activity through the high accessible surface area of the incorporated activated carbon of about 570 m² g⁻¹, thereby enabling a new approach toward sustainable water treatment processes. Due to the interplay of the components, it is possible to adsorb target substances, dissolved in the water which is demonstrated by the adsorption of the model dye methylene blue. A very fast adsorption kinetic and an adsorption capacity of about 400 mg g⁻¹ is determined. By using the developed composite particles, it is also possible to electrochemically alter substances flowing through a magnetically-stabilized fluidized-bed reactor by electrochemically charging/discharging, significantly supported by the magnetic field enabling alternatingly optimum mobility/adsorption phases with contact/charging intervals. The electrochemical conversion can be increased up to 151% depending on the applied flow-rate and electrical voltage. By applying an external magnetic field, a further increase of electrochemical conversion of up to 70% can be observed.     

Study of the Cathode Sheath Dynamics After Arc Current Zero Crossing Using a Two-Dimensional Langmuir Probe System

Russian Physics Journal - A two-dimensional system of miniature Langmuir probes operating in the electron saturation current mode is proposed. With its help, the spatial distribution of plasma...